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9篇 您的检索式:作者名="Hasimoto S"
    题名 作者 年代 出处 被引量
1The treatment of osteoporot-ic-posttraumatic vertebral collapse using the Kaneda device and a bioactive ceramic vertebral prosthesis显示文摘Kaneda K Asano S Hasimoto T 1992Spine1992,17,1:1
2显示文摘Hasimoto S Ochiai Y 1990Magn Magn Mater1990,88,:1
3Genotypes of canine distemper virus determined by analysis of the hemagglutinin genes of recent isolates from dogs in Japan显示文摘Mochizuki M Hasimoto M Hagiwara S 1999Clinical Microbiol1999,37,9:1
4Pyogenic hepatic abscess results of current management显示文摘Hasimoto L Hermann R Grundrest-Broniatowski S 1996Am Surg1996,61,:1
5Pyogenic hepatic abscess;results of current management显示文摘Hasimoto L Hermann R Grundrest-Broniatowski S 1996Am Surg1996,61,:1
6Behavior of Tricyclazole Residue on Rice Leaves and its Efficacy for Rice Blast Control in the Field 显示文摘KIYOSHI I TAKECHI S HASIMOTO 1992Ann Phytopathol Soc Jpn1992,58,:1
7A simple method for opening an obstructed peritoneal catheter using an infusion accelerator显示文摘Hasimoto Y Yano S Rkanishi Y 1996Adv Petit Dial1996,12,:1
8Syndemic aspects between COVID-19 pandemic and social inequalities显示文摘Although the coronavirus disease 2019(COVID-19)pandemic has reached all over the world population,it has demonstrated a heterogeneous impact on different populations.The most vulnerable communities which coexist daily with the social inequalities like low access to hygiene and personal protection products,crowded residences,and higher levels of chronic diseases have a higher risk of contact and the spread of infection,beyond unfavorable clinical outcomes.The elevation of the risk of infection exposure can be related to gender due to the presence of a larger contingent of women in essential services,as well as frontline and cleaning professionals who regardless of gender have the greatest exposure to the virus.Such exposures can contribute to the development of fear of contaminating themselves or their family members associated also with the work stress,both of which are related to the emergence of mental disturbances in these populations.Furthermore,conditions of unsanitary living and low socioeconomic status,populations at war,pre-existing social barriers,and ethnicity have contributed to more impact of the pandemic both in the exposure to the virus and access to health services,COVID-19 management,and management of other pathologies.At the same time,factors such as the closing of non-essential services,the loss of jobs,and the increase in household spending aggravated the social vulnerabilities and impacted the family economy.Lastly,the COVID-19 pandemic contributed still more to the impact on women's health since it propitiated a favorable environment for increasing domestic violence rates,through the segregation of women from social life,and increasing the time of the victims with their aggressors.Jonathan Santos Apolonio Ronaldo Teixeira da Silva Júnior Beatriz Rocha Cuzzuol Glauber Rocha Lima Araújo Hanna Santos Marques Isadora de Souza Barcelos Luana Kauany de SáSantos Luciano Hasimoto Malheiro Vinícius Lima de Souza Gonçalves Fabrício Freire de Melo 2022World Journal of Methodology2022,12,5:0
9Usher syndrome:Genetic diagnosis and current therapeutic approaches显示文摘Usher Syndrome(USH)is the most common deaf-blind syndrome,affecting approximately 1 in 6000 people in the deaf population.This genetic condition is characterized by a combination of hearing loss(HL),retinitis pigmentosa,and,in some cases,vestibular areflexia.Among the subtypes of USH,USH type 1 is considered the most severe form,presenting profound bilateral congenital deafness,vestibular areflexia,and early onset RP.USH type 2 is the most common form,exhibiting congenital moderate to severe HL for low frequencies and severe to profound HL for high frequencies.Conversely,type 3 is the rarest,initially manifesting mild symptoms during childhood that become more prominent in the first decades of life.The dual impact of USH on both visual and auditory senses significantly impairs patients'quality of life,restricting their daily activities and interactions with society.To date,9 genes have been confirmed so far for USH:MYO7A,USH1C,CDH23,PCDH15,USH1G,USH2A,ADGRV1,WHRN and CLRN1.These genes are inherited in an autosomal recessive manner and encode proteins expressed in the inner ear and retina,leading to functional loss.Although non-genetic methods can assist in patient triage and disease extension evaluation,genetic and molecular tests play a pivotal role in providing genetic counseling,enabling appropriate gene therapy,and facilitating timely cochlear implantation(CI).The CRISPR/Cas9 system and viral-based gene replacement therapy have recently emerged as highly promising techniques for treating USH.Regarding drug therapy,PTC-124 and Nb54 have been identified as promising drug interventions for genetic HL in USH.Simultaneously,CI has proven to be critical in the restoration of hearing.This review aims to summarize the genetic and molecular diagnosis of USH and highlight the importance of early diagnosis in Cuzzuol BR et al.Diagnosis and current treatments of USH WJO https://www.wjgnet.com 2 January 19,2024 Volume 11 Issue 1 guiding appropriate treatment strategies and improving patient prognosis.Beatriz Rocha Cuzzuol Jonathan Santos Apolonio Ronaldo Teixeira da Silva Júnior Lorena Sousa de Carvalho Luana Kauany de SáSantos Luciano Hasimoto Malheiro Marcel Silva Luz Mariana Santos Calmon Henrique de Lima Crivellaro Fabian Fellipe Bueno Lemos Fabrício Freire de Melo 2024World Journal of Otorhinolaryngology2024,11,1:0
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