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| 1 | Urine-derived stem/progenitor cells:A focus on their characterization and potential显示文摘Cell therapy,i.e.,the use of cells to repair an affected tissue or organ,is at the forefront of regenerative and personalized medicine.Among the multiple cell types that have been used for this purpose[including adult stem cells such as mesenchymal stem cells or pluripotent stem cells],urine-derived stem cells(USCs)have aroused interest in the past years.USCs display classical features of mesenchymal stem cells such as differentiation capacity and immunomodulation.Importantly,they have the main advantage of being isolable from one sample of voided urine with a cheap and unpainful procedure,which is broadly applicable,whereas most adult stem cell types require invasive procedure.Moreover,USCs can be differentiated into renal cell types.This is of high interest for renal cell therapy-based regenerative approaches.This review will firstly describe the isolation and characterization of USCs.We will specifically present USC phenotype,which is not an object of consensus in the literature,as well as detail their differentiation capacity.In the second part of this review,we will present and discuss the main applications of USCs.These include use as a substrate to generate human induced pluripotent stem cells,but we will deeply focus on the use of USCs for cell therapy approaches with a detailed analysis depending on the targeted organ or system.Importantly,we will also focus on the applications that rely on the use of USC-derived products such as microvesicles including exosomes,which is a strategy being increasingly employed.In the last section,we will discuss the remaining barriers and challenges in the field of USC-based regenerative medicine. | Perrine Burdeyron Sébastien Giraud Thierry Hauet Clara Steichen | 2020 | World Journal of Stem Cells2020，12，10： | 6 |
| 2 | Mitochondria as target for antiischemic drugs显示文摘 | Morin D Hauet T Spedding M Tillement J | 2001 | Adv Drug Deliv Rev2001，49，12： | 2 |
| 3 | To use MIBI or not to use MIBI? That is the question when assessing tumor cells 显示文摘 | Moretti JL Hauet N Caglar M | 2005 | Eur J Nucl Med Mol Imaging2005，32，7： | 1 |
| 4 | Renal protective effect of metabolic therapy in patients with coronary artery disease and diabetes: from bench to bed side 显示文摘 | THUILLIER R TILLEMENT J P HAUET T | 2009 | Curt Pharm Des2009，15，8： | 1 |
| 5 | Mitochondria as tar-get for antiischemic drugs 显示文摘 | Morin D Hauet T Spedding M | 2001 | Adv Drug Delivery Res2001，49，： | 1 |
| 6 | To use MIBI or not to use MIBI? That is the question when assessing tumour cells显示文摘 | Jean-Luc Moretti Nathalie Hauet Meltem Caglar Olivier Rebillard Zeynep Burak | 2005 | European Journal of Nuclear Medicine and Molecular Imaging2005，，7： | 1 |
| 7 | To use MIBI or not to use MIBI? That is the question when assessing tumor ceils 显示文摘 | Moretti JL Hauet N Caglar M | 2005 | Eur J Nucl Med Mol Imaging2005，32，7： | 1 |
| 8 | Attenuation of endoplasmic reticulum stress and mitochondrial injury in kidney with ischemic postconditioning application and trimetazidine treatment显示文摘 | Mahfoudh-Boussaid A Zaouali MA Hauet T | 2012 | J Biomed Sci2012，19，： | 1 |
| 9 | Trimetazidine prevents renal injury in the isolated perfused pig kidney exposed to prolonged cold ischemia显示文摘 | Hauet T Mothes D Goujon JM | 1997 | Transplantation1997，64，7： | 1 |
| 10 | Application and Evaluation of LS-PIV Technique for the Monitoring of River Surface Velocities in High Flow Conditions显示文摘 | Jodeau M Hauet A Paquier A | 2008 | Flow Measurement and Instrumentation2008，19，： | 1 |
| 11 | Application and evaluation of LS-PIV technique for the monitoring of river surface velocities in high flow conditions显示文摘 | JODEAU M HAUET A PAQUIER A | 2008 | Flow Measurement and Instrumentation2008，19，2： | 1 |
| 12 | Performance of image-based velocimetry (LSPIV) applied to flash-flood discharge measurements in Mediterranean rivers显示文摘 | COZ J L HAUET A PIERREFEU G | 2010 | Journal of Hydrology2010，394，1： | 1 |
| 13 | Mitocbondria as target for antiischemic drugs显示文摘 | ?AMorin D Hauet T Spedding M | 2001 | Adv Drug Deliv Rev2001，49，12： | 1 |
| 14 | Role of translocator protein in renal ischemiareperfusion,renal preservation and acute kidney injury 显示文摘 | Thuillier H Hauet T | 2012 | CurrMol Med2012，12，41： | 1 |
| 15 | Attenuation ofendoplasmic reticulum stress and mitochondrial injury in kidneywith ischemic postconditioning application and trimetazidinetreatment显示文摘 | Mahfoudh-Boussaid A Zaouali M A Hauet T | 2012 | J Biomed Sci2012，19，： | 1 |
| 16 | To use MIBI or not to use MIBI? That is the question when assessing tumour eells显示文摘 | Moretti JL Hauet N Caglar M | 2005 | Eur J Nuel Med Mol Imaging2005，32，7： | 1 |
| 17 | Trimetazidine reduces re- nal dysfunction by limiting the cold ischemia/reperfusion injury in autotransplanted pig kidneys显示文摘 | Hauet T Goujon JM Vandewalle A | 2000 | J Am Soc Nephrol2000，11，1： | 1 |
| 18 | Attenuation of endoplasmic reticulum stress and mitochondrial injury in kidney with ischemie postconditioning application and trimetazidine treatment 显示文摘 | Mahfoudh-Boussaid A Zaouali MA Hauet T | 2012 | J Biomed Sci2012，19，： | 1 |
| 19 | Large-scale particleimage velocimetry for measurements in riverineenvironments显示文摘 | MUSTE M FUJITA I HAUET A | 2008 | Water Resources Research2008，44，： | 1 |
| 20 | Mitoehondria as target for antiischemie drugs显示文摘 | Morin D Hauet T Spedding M | 2001 | Adv Drug Delivery Res2001，49，： | 1 |
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