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| 1 | Correlation of endoscopic disease severity with pediatric ulcerative colitis activity index score in children and young adults with ulcerative colitis显示文摘AIM To investigate of pediatric ulcerative colitis activity index(PUCAI) in ulcerative colitis correlate with mucosal inflammation and endoscopic assessment of disease activity(Mayo endoscopic score).METHODS We reviewed charts from ulcerative colitis patients who had undergone both colonoscopy over 3 years. Clinical assessment of disease severity within 35 d(either before or after) the colonoscopy were included. Patients were excluded if they had significant therapeutic interventions(such as the start of corticosteroids or immunosuppressive agents) between the colonoscopy and the clinical assessment. Mayoendoscopic score of the rectum and sigmoid were done by two gastroenterologists. Inter-observer variability in Mayo score was assessed.RESULTS We identified 99 patients(53% female, 74% pancolitis) that met inclusion criteria. The indications for colonoscopy included ongoing disease activity(62%), consideration of medication change(10%), assessment of medication efficacy(14%), and cancer screening(14%). Based on PUCAI scores, 33% of patients were in remission, 39% had mild disease, 23% had moderate disease, and 4% had severe disease. There was 'moderate-substantial' agreement between the two reviewers in assessing rectal Mayo scores(kappa = 0.54, 95%CI: 0.41-0.68). CONCLUSION Endoscopic disease severity(Mayo score) assessed by reviewing photographs of pediatric colonoscopy has moderate inter-rater reliability, and agreement was less robust in assessing patients with mild disease activity. Endoscopic disease severity generally correlates with clinical disease severity as measured by PUCAI score. However, children with inflamed colons can have significant variation in their reported clinical symptoms. Thus, assessment of both clinical symptoms and endoscopic disease severity may be required in future clinical studies. | Basavaraj Kerur Heather J Litman Julia Bender Stern Sarah Weber Jenifer R Lightdale Paul A Rufo Athos Bousvaros | 2017 | World Journal of Gastroenterology2017，23，18： | 5 |
| 2 | A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010显示文摘 | Stephen S Lim Theo Vos Abraham D Flaxman Goodarz Danaei Kenji Shibuya Heather Adair-Rohani Mohammad A AlMazroa Markus Amann H Ross Anderson Kathryn G Andrews Martin Aryee Charles Atkinson Loraine J Bacchus Adil N Bahalim Kalpana Balakrishnan John Balmes S | 2012 | 2012 (9859)2012，，9859： | 3 |
| 3 | Abdominal ultrasonography of the pediatric gastrointestinal tract显示文摘Ultrasound is an invaluable imaging modality in the evaluation of pediatric gastrointestinal pathology; it can provide real-time evaluation of the bowel without the need for sedation or intravenous contrast. Recent improvements in ultrasound technique can be utilized to improve detection of bowel pathology in children: Higher resolution probes, color Doppler, harmonic and panoramic imaging are excellent tools in this setting. Graded compression and cine clips provide dynamic information and oral and intravenous contrast agents aid in detection of bowel wall pathology. Ultrasound of the bowel in children is typically a targeted exam; common indications include evaluation for appendicitis, pyloric stenosis and intussusception. Bowel abnormalities that are detected prenatally can be evaluated after birth with ultrasound. Likewise, acquired conditions such as bowel hematoma, bowel infections and hernias can be detected with ultrasound. Rare bowel neoplasms, vascular disorders and foreign bodies may first be detected with sonography, as well. At some centers, comprehensive exams of the gastrointestinal tract are performed on children with inflammatory bowel disease and celiac disease to evaluate for disease activity or to confirm the diagnosis. The goal of this article is to review up-to-date imaging techniques, normal sonographic anatomy, and characteristic sonographic features of common and uncommon disorders affecting the gastrointestinal tract in children. | Heather I Gale Michael S Gee Sjirk J Westra Katherine Nimkin | 2016 | World Journal of Radiology2016，8，7： | 3 |
| 4 | Statins and risk of incident diabetes: a collaborative meta-analysis of randomised statin trials显示文摘 | Naveed Sattar David Preiss Heather M Murray Paul Welsh Brendan M Buckley Anton JM de Craen Sreenivasa Rao Kondapally Seshasai John J McMurray Dilys J Freeman J Wouter Jukema Peter W Macfarlane Chris J Packard David J Stott Rudi G Westendorp James Shepherd | 2010 | The Lancet2010，，9716： | 2 |
| 5 | A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010显示文摘 | Stephen S Lim Theo Vos Abraham D Flaxman Goodarz Danaei Kenji Shibuya Heather Adair-Rohani Mohammad A AlMazroa Markus Amann H Ross Anderson Kathryn G Andrews Martin Aryee Charles Atkinson Loraine J Bacchus Adil N Bahalim Kalpana Balakrishnan John Balmes S | 2012 | The Lancet2012，，9859： | 2 |
| 6 | Statins and risk of incident diabetes: a collaborative meta-analysis of randomised statin trials显示文摘 | Naveed Sattar David Preiss Heather M Murray Paul Welsh Brendan M Buckley Anton JM de Craen Sreenivasa Rao Kondapally Seshasai John J McMurray Dilys J Freeman J Wouter Jukema Peter W Macfarlane Chris J Packard David J Stott Rudi G Westendorp James Shepherd | 2010 | The Lancet2010，，9716： | 2 |
| 7 | Randomised trial of flush saphenofemoral ligation for primary great saphenous varicose veins 显示文摘 | WINTERBORN R J FOY C HEATHER B P | 2008 | Eur J Vasc Endovasc Surg2008，36，4： | 1 |
| 8 | Fiber grating sensors显示文摘 | Alan D K Michael A D Heather J P | 1997 | J Lightwave Technol1997，15，8： | 1 |
| 9 | Studies on the microbial populations of the rhizosphere of big sagebrush (Artemisia tridentata)显示文摘 | Antony J B Janice L S Heather M K | 2004 | Journal Indian Microbiology and Biotechnology2004，31，6： | 1 |
| 10 | Glasgow Coma Scale and outcomes after structural traumatic head injury in early childhood显示文摘 | Heather NL Derraik JG Beca J | | 0，，12： | 1 |
| 11 | A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010显示文摘 | Stephen S Lim Theo Vos Abraham D Flaxman Goodarz Danaei Kenji Shibuya Heather Adair-Rohani Mohammad A AlMazroa Markus Amann H Ross Anderson Kathryn G Andrews Martin Aryee Charles Atkinson Loraine J Bacchus Adil N Bahalim Kalpana Balakrishnan John Balmes S | 2012 | The Lancet . 2012 (9859)2012，，9859： | 1 |
| 12 | Risk of heart failure in breast cancer patients after anthracycline and trastuzumab treatment:a retrospective cohort study显示文摘 | Erin J Aiello Bowles Robert Wellman Heather Spencer | 2012 | Journal of the National Cancer Institute2012，104，17： | 1 |
| 13 | Corpus callosum in maltreated children with posttraumatic stress disorder:A diffusion tensor imaging study显示文摘 | Andrea PJ Heather DP Marcel J | 2008 | Psychiatry Research:Neuroimaging2008，162，3： | 1 |
| 14 | Photocatalytic degradation of 17-β-oestradiol on immobilised TiO2 显示文摘 | Heather MC Brian RE J Anthony B | 2000 | Applied Catalysis B : Environmental2000，24，1： | 1 |
| 15 | Benign breast disease,recent alcohol consumption,and risk of breast cancer:a nested case-control study显示文摘 | Rulla M Tamimi Celia Byrne Heather J Baer | 2005 | Breast Cancer Res2005，7，4： | 1 |
| 16 | Stochastic Population Forecasts Using Functional Data Models for Mortality Fertilityand Migration显示文摘 | Hyndman Rob J Heather Booth | 2008 | International Journal of Forecasting2008，24，： | 1 |
| 17 | Calcium signaling in Arabidopsis thaliana responding to drought and salinity 显示文摘 | HEATHER K ANTHONY J MARC R K | 1997 | The Plant Journal1997，12，： | 1 |
| 18 | Determination of carbendazim in blue berries by reversed phase high 2 perfomance liquid chromatography显示文摘 | Rodney J B Heather L H Jasotha K | 1991 | Journal of Chromatography1991，，587： | 1 |
| 19 | Fiber grating sensor显示文摘 | KERSEY A D MICHAEL A D HEATHER J P | 1997 | Lightwave Technol1997，15，8： | 1 |
| 20 | GibsonSport Tourism : A Critical Analysis of Research 显示文摘 | Heather J | 1998 | Sport Management Review1998，1，1： | 1 |
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