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38篇 您的检索式:作者名="Hedin G"
    题名 作者 年代 出处 被引量
1Tissue-specific transcriptional imprinting and heterogeneity in human innate lymphoid cells revealed by full-length single-cell RNA-sequencing显示文摘The impact of the microenvironment on innate lymphoid cell(ILC)-mediated immunity in humans remains largely unknown.Here we used full-length Smart-seq2 single-cell RNA-sequencing to unravel tissue-specific transcriptional profiles and heterogeneity of CD127+ILCs across four human tissues.Correlation analysis identified gene modules characterizing the migratory properties of tonsil and blood ILCs,and signatures of tissue-residency,activation and modified metabolism in colon and lung ILCs.Trajectory analysis revealed potential differentiation pathways from circulating and tissue-resident naïve ILCs to a spectrum of mature ILC subsets.In the lung we identified both CRTH2+and CRTH2−ILC2 with lung-specific signatures,which could be recapitulated by alarmin-exposure of circulating ILC2.Finally,we describe unique TCR-V(D)J-rearrangement patterns of blood ILC1-like cells,revealing a subset of potentially immature ILCs with TCR-δ rearrangement.Our study provides a useful resource for in-depth understanding of ILC-mediated immunity in humans,with implications for disease.Luca Mazzurana Paulo Czarnewski Viktor Jonsson Leif Wigge Markus Ringnér Teresa CWilliams Avinash Ravindran Åsa KBjörklund Jesper Säfholm Gunnar Nilsson Sven-Erik Dahlén Ann-Charlotte Orre Mamdoh Al-Ameri Charlotte Höög Charlotte Hedin Sylwester Szczegielniak Sven Almer Jenny Mjösberg 2021Cell Research2021,31,5:2
2Attraction of the larval predator Elater ferrugineus to the sex pheromone of its prey, Osmoderma eremita, and its implication for conservation biology 显示文摘Svensson G P Larsson M C Hedin J 2004Journal of Chemical Ecology2004,30,:1
3Atmospheric dust and acid rain显示文摘Hedin L O Likens G E 1996Scientific American1996,12,:1
4Changes in the chemistry of surface waters 显示文摘Driscoll C T Likens G E Hedin L O 1989Environmental Science and Technology1989,23,2:1
5Occurrence of potentially pathogenic bacteria on the hands of hospital patients before and after the introduction of patient hand disinfection显示文摘Hedin G Blomkvist A Janson M 2012APMIS2012,120,10:1
6Diverse effects of heparin on mitogen-activated protein kinase-dependent signal transduction in vascular smooth muscle cells显示文摘Daum G Hedin U Wang YX 1997Circulation Res1997,1,:1
7Treatment with foscarnet of fulminant hepatitis B and D coninfection显示文摘HEDIN G WEILAND O KARIN LJ 1988Viral Hepatitis and Diseases1988,38,:1
8Diverse effects of heparin on mitogen-activated protein kinase-dependent signal transduction in vascular smooth muscle cells显示文摘DAUM G HEDIN U WANG Y 1997Circ Res1997,81,1:1
9Diverse effects of heparin on mitogen-activated protein kinase-dependent signal transduction in vascular smooth muscle cells 显示文摘Daum G Hedin U Wang Y 1997Circ Res1997,81,1:1
10Molecular epidemiology of extended-spectrum β-lactamases among Escherichia coll isolates collected in a Swedish hospital and its associated health care facilities from 2001 to 2006显示文摘Fang H Ataker F Hedin G 2008J Clin Microbiol2008,46,2:1
11Rapid screening and identification of methicillin-resistant Staphylococcus aztreus from clinical samples by selective-broth and real-time PCR assay显示文摘Fang H Hedin G 2003Clin Microbiol2003,41,7:1
12Rapid screening and identification of methicillin-resistant Staphylococcus aureus from clinical samples by selective-broth and real-time PCR assay显示文摘Fang H Hedin G 2003J Clin Microbiol2003,41,7:1
13Molecular epidemiology of extended-spectrum beta-lactamases among Escherichia coli iso- lates collected in a Swedish hospital and its associated health care facilities from 2001 to 2006 显示文摘Fang H Ataker F Hedin G 2008J Clin Microbiol2008,46,2:1
14Molecular epidemiology of extended-spectrum fl-lactamases among Escheriehia coli isolates collected in a Swedish hospital and its associated health care facilities from 2001 to 2006显示文摘Fang H Ataker F Hedin G 2008Journal of Clinical Microbiology2008,46,2:1
15Densities of large living and dead trees in old-growth temperate and boreal forests显示文摘NILSSON S G NIKLASSON M HEDIN J 2002Forest Ecology and Management2002,161,13:1
16Identification and field evaluation of the componds comprising the sex pheromone of the female boll weevil 显示文摘HEDIN P A MCKBBEN G H MITCHELL E B 1979Journal of Chemical Ecology1979,5,:1
17Extending languages by leveraging compilers: From modelica to optimica显示文摘HEDIN G AKESSEN J EKMAN T 2011IEEE Sottware2011,28,3:1
18Complex re- sponse of the forest nitrogen cycle to climate change显示文摘BERNAL S HEDIN L O LIKENS G E 2012Pro- ceedings of the National Academy of Sciences2012,109,9:1
19Heparin inhibits thrombin-induced mitogen-activated protein kinase signaling in arterial smooth muscle cel ls显示文摘Hedin U Daum G Clowes A W 1998J Vasc Surg1998,27,:1
20Molecular epidemiology of extended-spectrum 13-1aetamases among Escheriehia coli isolates collected in a Swedish hospital and its associated health care facilities from 2001 to 2006 显示文摘Fang H Ataker F Hedin G 2008J Clin Microbiol2008,46,2:1
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