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| 1 | Dental and periodontal phenotype in sclerostin knockout mice显示文摘Sclerostin is a Wnt signalling antagonist that controls bone metabolism.Sclerostin is expressed by osteocytes and cementocytes;however,its role in the formation of dental structures remains unclear.Here,we analysed the mandibles of sclerostin knockout mice to determine the influence of sclerostin on dental structures and dimensions using histomorphometry and micro-computed tomography(mCT)imaging.mCT and histomorphometric analyses were performed on the first lower molar and its surrounding structures in mice lacking a functional sclerostin gene and in wild-type controls.mCT on six animals in each group revealed that the dimension of the basal bone as well as the coronal and apical part of alveolar part increased in the sclerostin knockout mice.No significant differences were observed for the tooth and pulp chamber volume.Descriptive histomorphometric analyses of four wild-type and three sclerostin knockout mice demonstrated an increased width of the cementum and a concomitant moderate decrease in the periodontal space width.Taken together,these results suggest that the lack of sclerostin mainly alters the bone and cementum phenotypes rather than producing abnormalities in tooth structures such as dentin. | Ulrike Kuchler Uwe Y Schwarze Toni Dobsak Patrick Heimel Dieter D Bosshardt Michaela Kneissel Reinhard Gruber | 2014 | International Journal of Oral Science2014，6，2： | 7 |
| 2 | The transplacental passage of prednisolone in pregnancies complicated by early-onset HELLP syndrome显示文摘 | van Runnard Heimel PJ Schobben AF Huisjes A J | | 0，，10： | 1 |
| 3 | Induction of necrosis and DNA fragmentation during hypothermic preservation of hepatocytes in UW, HTK, and Celsior solutions显示文摘 | Abrahamse S L van Runnard Heimel P Hartman R J | 2003 | Cell Transplant2003，12，1： | 1 |
| 4 | Sound speed, density and total protein concentration of blood 显示文摘 | SCHNEDITZ D HEIMEL H STABINGER H | 1989 | J Clin Chem Clin Biochem1989，27，10： | 1 |
| 5 | Interventions for Intrauterine Resuscitation in Suspected Fetal Distress During Term Labor: A Systematic Re- view显示文摘 | Bullens LM van Runnard Heimel PJ van der Hour-van der Jagt MB | 2015 | Obstet GynecolSurv2015，70，8： | 1 |
| 6 | Corticosteroids,pregnancy,and HELLP syndrome:a review显示文摘 | van Runnard Heimel PJ Franx A Schobben AF | 2005 | Obstet Gynecol Surv2005，60，1： | 1 |
| 7 | Mapping of FASN and ACACA on two chicken microchromosomes disrupts the human 17q syntenic group well conserved in mammals显示文摘 | Pitel F Fillon V Heimel C | 1998 | Mamm Genome1998，9，4： | 1 |
| 8 | SNOM/STM using a tetrahedral tip and a sensitive current-to-voltage converter显示文摘 | Heimel J Fischer U C Fuchs H | 2001 | Journal of Microscopy-oxford2001，202，： | 1 |
| 9 | Hie Clpl protein is required forclamp formation and pathogenic development of Ustilago maydis显示文摘 | SchererM Starke V Heimel K | 2006 | Plant Cell2006，18，9： | 1 |
| 10 | Lack of patchy horizontal connectivity in primary visual cortex of a mammal without orientation maps 显示文摘 | Van Hooser S D Heimel J A Chung S | 2006 | The Journal of Neuroscience2006，26，29： | 1 |
| 11 | Modeling the elec- tronic properties of pi-eonjugated self-assembled monolayers显示文摘 | Heimel G Rissner F Zojer E | 2010 | Adv Mat2010，22，23： | 1 |
| 12 | Acute activation of the endothehum results in increased levels of active yon Willebrand factor in hemolysis, elevated liver en- zymes and low platelets ( HELLP ) syndrome 显示文摘 | HULSTEIN J J VAN RUNNARD HEIMEL P J FRANX A etal | 2006 | J Thromb Haemost2006，4，12： | 1 |
| 13 | The role of GABAergic inhibition in ocular Dominance plasticity显示文摘 | Heimel JA van Versendaal D Leveh CN | 2011 | Neural Plast2011，2011，39： | 1 |
| 14 | Devel-opment of the Pregnancy and Childbirth Questionnaire (PCQ):evaluating quality of care as perceived by women who recentlygave birth 显示文摘 | Truijens SE Pommer AM van Runnard Heimel PJ | 2014 | Eur J Obstet Gynecol Reprod Biol2014，174，： | 1 |
| 15 | The transcription factor Rbfl is the master regulator for b-mating type con- trolled pathogenic development in Ustilago maydis显示文摘 | Heimel K Scherer M Vranes M | 2010 | PLoS Pathog2010，6，00： | 1 |
| 16 | Screening mouse vision with intrinsic signal optical imaging显示文摘 | Heimel JA Hartman R J Hermans JM | 2007 | Eur J Neurosci2007，25，3： | 1 |
| 17 | Interventions for Intrauterine Resuscitation in Suspected Fetal Distress During Term Labor:A Systematic Review显示文摘 | Bullens LM van Runnard Heimel PJ van der Hout-van der Jagt MB | 2015 | Obstetrical&gynecological survey2015，70，8： | 1 |
| 18 | The Ustilago maydis Clpl protein orchestrates pheromone and b- dependent signaling pathways to coordinate the cell cycle and pathogenic development显示文摘 | Heimel K Scherer M Schuler D | 2010 | Plant Cell2010，22，8： | 1 |
| 19 | The transplacental passage of prednisolone in pregnancies complicated by early-onset hellp syndrome 显示文摘 | van Runnard Heimel PJ Schobben AF Huisjes A J | 2005 | Placenta2005，26，10： | 1 |
| 20 | Acute activation of the endothelium results in increased levels of active von Willebrand factor in hemolysis,elevated liver enzymes and low platelets(HELLP)syndrome显示文摘 | HULSTEIN JJ VAN RUNNARD HEIMEL PJ FRANX A | 2006 | J Thromb Haemost2006，4，12： | 1 |
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