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1篇 您的检索式:作者名="Heling Jiang"
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1CIDP: a multi-functional platform for designing CRISPR sgRNAs显示文摘Dear Editor,Compared with traditional technologies affecting gene expression,changing DNA sequences of target genes is one of the most outstanding characters of CRISPR(Clustered Regularly Interspaced Short Palindromic Repeats).Single-guide RNAs(sgRNAs)guiding endonuclease Cas to target sites is a crucial step of CRISPR-Cas system for changing DNA sequences.An ideal sgRNA should only bind to the target gene.However,similar sequences of non-target sites can also be recognized leading to off-target effects[1].Dong Xu Jin Zhang Xianjia Zhao Yuze Hou Heling Jiang Wenchuang He Xiongfeng Ma Weihua Pan 2023Horticulture Research2023,10,7:0
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