|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Magnesium based surface metal matrix composites by friction stir processing显示文摘Surface metal matrix composites(MMCs)are a group of modern engineered materials where the surface of the material is modified by dispersing secondary phase in the form of particles or fibers and the core of the material experience no change in chemical composition and structure.The potential applications of the surface MMCs can be found in automotive,aerospace,biomedical and power industries.Recently,friction stir processing(FSP)technique has been gaining wide popularity in producing surface composites in solid state itself.Magnesium and its alloys being difficult to process metals also have been successfully processed by FSP to fabricate surface MMCs.The aim of the present paper is to provide a comprehensive summary of state-of-the-art in fabricating magnesium based composites by FSP.Influence of the secondary phase particles and grain refinement resulted from FSP on the properties of these composites is also discussed. | B.Ratna Sunil G.Pradeep Kumar Reddy Hemendra Patle Ravikumar Dumpala | 2016 | Journal of Magnesium and Alloys2016，4，1： | 6 |
| 2 | Temporal changes in inflammatory mitochondria-enriched microRNAs following traumatic brain injury and effects of miR-146a nanoparticle delivery显示文摘MicroRNAs(miRNAs)are small non-coding RNA molecules that regulate post-transcriptional gene expression and contribute to all aspects of cellular function.We previously reported that the activities of several mitochondria-enriched miRNAs regulating inflammation(i.e.,miR-142-3p,miR-142-5p,and miR-146a)are altered in the hippocampus at 3–12 hours following a severe traumatic brain injury.In the present study,we investigated the temporal expression profile of these inflammatory miRNAs in mitochondria and cytosol fractions at more chronic post-injury times following severe controlled cortical impact injury in rats.In addition,several inflammatory genes were analyzed in the cytosol fractions.The analysis showed that while elevated levels were observed in cytoplasm,the mitochondria-enriched miRNAs,miR-142-3p and miR-142-5p continued to be significantly reduced in mitochondria from injured hippocampi for at least 3 days and returned to near normal levels at 7 days post-injury.Although not statistically significant,miR-146a also remained at reduced levels for up to 3 days following controlled cortical impact injury,and recovered by 7 days.In contrast,miRNAs that are not enriched in mitochondria,including miR-124a,miR-150,miR-19b,miR-155,and miR-223 were either increased or demonstrated no change in their levels in mitochondrial fractions for 7 days.The one exception was that miR-223 levels were reduced in mitochondria at 1 day following injury.No major alterations were observed in sham operated animals.This temporal pattern was unique to mitochondria-enriched miRNAs and correlated with injury-induced changes in mitochondrial bioenergetics as well as expression levels of several inflammatory markers.These observations suggested a potential compartmental re-distribution of the mitochondria-enriched inflammatory miRNAs and may reflect an intracellular mechanism by which specific miRNAs regulate injury-induced inflammatory signaling.To test this,we utilized a novel peptide-based nanoparticle strategy for in vitro and in vivo delivery of a miR-146a mimic as a potential therapeutic strategy for targeting nuclear factor-kappa B inflammatory modulators in the injured brain.Nanoparticle delivery of miR-146a to BV-2 or SH-SY5Y cells significantly reduced expression of TNF receptor-associated factor 6(TRAF6)and interleukin-1 receptor-associated kinase 1(IRAK1),two important modulators of the nuclear factor-kappa B(NF-κB)pro-inflammatory pathway.Moreover,injections of miR-146a containing nanoparticles into the brain immediately following controlled cortical impact injury significantly reduced hippocampal TNF receptor-associated factor 6 and interleukin-1 receptor-associated kinase 1 levels.Taken together,our studies demonstrate the subcellular alteration of inflammatory miRNAs after traumatic brain injury and establish proof of principle that nanoparticle delivery of miR-146a has therapeutic potential for modulating pro-inflammatory effectors in the injured brain.All of the studies performed were approved by the University of Kentucky Institutional Animal Care and Usage Committee(IACUC protocol#2014-1300)on August 17,2017. | Wang-Xia Wang Paresh Prajapati Hemendra J.Vekaria Malinda Spry Amber L.Cloud Patrick G.Sullivan Joe E.Springer | 2021 | Neural Regeneration Research2021，16，3： | 3 |
| 3 | Ultrathin tunable terahertz absorber based on MEMS-driven metamaterial显示文摘The realization of high-performance tunable absorbers for terahertz frequencies is crucial for advancing applications such as single-pixel imaging and spectroscopy.Based on the strong position sensitivity of metamaterials’electromagnetic response,we combine meta-atoms that support strongly localized modes with suspended flat membranes that can be driven electrostatically.This design maximizes the tunability range for small mechanical displacements of the membranes.We employ a micro-electromechanical system technology and successfully fabricate the devices.Our prototype devices are among the best-performing tunable THz absorbers demonstrated to date,with an ultrathin device thickness(~1/50 of the working wavelength),absorption varying between 60%and 80%in the initial state when the membranes remain suspended,and fast switching speed(~27μs).The absorption is tuned by an applied voltage,with the most marked results achieved when the structure reaches the snap-down state.In this case,the resonance shifts by >200% of the linewidth(14% of the initial resonance frequency),and the absolute absorption modulation measured at the initial resonance can reach 65%.The demonstrated approach can be further optimized and extended to benefit numerous applications in THz technology. | Mingkai Liu Mohamad Susli Dilusha Silva Gino Putrino Hemendra Kala Shuting Fan Michael Cole Lorenzo Faraone Vincent P.Wallace Willie J.Padilla David A.Powell Ilya V.Shadrivov Mariusz Martyniuk | 2017 | Microsystems & Nanoengineering2017，3，1： | 2 |
| 4 | An unusual cause of radial nerve palsy显示文摘Neurapraxia 经常发生 intraoperatively 跟随拖拉损害到神经,导致通常在 5-30 星期内恢复的光线的神经麻痹。在我们的情况中,我们操作了一远侧三分之一个肱骨的柄断裂并且与 4.5 修理了它;公里限制了接触动态压缩板。手足的远侧的神经与血管的地位在恢复房间里手术后地被估计并且被发现未经触动并且光线的神经的所有感觉马达的功能是正常的。在第二手术后的天,跟随吸排水管移动和调味品,与手腕落下一起的耐心的发达立即的光线的神经麻痹。我们考察了文学并且没为神经麻痹发现明显的原因并且当在否定压力移开吸排水管时,断定它由于对光线的神经的拖拉损害。 | Hemendra Kumar Agrawal Vipin Khatkar Mohit Garg Balvinder Singh Ashish Jaiman Vinod Kumar Sharma | 2014 | Chinese Journal of Traumatology2014，17，3： | 2 |
| 5 | Prep- aration of Glycol Derivatives of Partially Hydrogenated Soy- bean Oil Fatty Acids and Their Potential as Lubricants 显示文摘 | Hemendra N Basu Wllen M Robley Max E Norris | 1994 | Journal of American Oil Chemical Society1994，71，11： | 1 |
| 6 | Impact of Case Volumes on the Outcomes of Percutaneous Nephrolithotomy显示文摘 | Dedan Opondo Ahmet Tefekli Tarik Esen Gaston Labate Kandasami Sangam Antonello De Lisa Hemendra Shah Jean de la Rosette | 2012 | European Urology2012，，6： | 1 |
| 7 | Benign prostate hyperplasia and bladder stones:an update 显示文摘 | Hemendra N Shah | 2013 | Current Bladder Dysfunction Reports2013，8，3： | 1 |
| 8 | Safety and effcacy of bilateral simultaneous tubeless percutaneous nephrolithtomy显示文摘 | Hemendra N Vikram B Sunil S at al | 2005 | Urology2005，66，： | 1 |
| 9 | Urinary tract infections and post-operative fever in percutaneous nephrolithotomy显示文摘 | Jorge Gutierrez Arthur Smith Petrisor Geavlete Hemendra Shah Ali Riza Kural Marco Sio José H. Amón Sesmero András Hoznek Jean Rosette | 2013 | World Journal of Urology2013，，5： | 1 |
| 10 | Extrarenal retroperitoneal angiomyolipoma显示文摘 | Jeffrey EF Hemendra RS Perkins M | 1997 | South Med J1997，90，： | 1 |
| 11 | Prospective e- valuation of unidirectional barbed suture for various indi- cations in surgeon-controlled robotic reconstructive uro- logic surgery: wake forest university experience 显示文摘 | Hemendra NS Rishi N Shrinivas R | 2012 | Int Urol Nephrol2012，44，： | 1 |
| 12 | CASE REPORT: Heterozygosity for Factor V Leiden and G20210A Prothrombin Genotypes in a Patient with Mesenteric Vein Thrombosis显示文摘 | Amar Al-Juburi Margie A. Scott Hemendra R. Shah Jean-Pierre Raufman | 2002 | Digestive Diseases and Sciences2002，，3： | 1 |
| 13 | Distribution of morphine in brain regions,spinal cord and serum following intravenous injection to morphine tolerant rats显示文摘 | HEMENDRA N VINCENT M NAFASAT H | 1992 | Brain Res1992，595，2： | 1 |
| 14 | Nutritional and potential disease prevention properties of carotenoids显示文摘 | Hemendra N Frank Flider Frank T Orthoeter | 2001 | Journal of the American Oil Chemists'' Society2001，78，7： | 1 |
| 15 | Safety and efficacy of bilateral simultaneous tubeless percutaneous nephrolithtomy显示文摘 | HEMENDRA N VIKRAM B SUNIL S | 2005 | Urology2005，66，： | 1 |
| 16 | Validation of a stability-indicating LC method for assay of ezetimibe in tablets and for determination of content uniformity 显示文摘 | ASHISH S D PANKAJ K K HEMENDRA S J | 2008 | Chromatographia2008，67，： | 1 |
| 17 | Simultaneous transurethral cystolithotripsy with holmium laser enucleation of the prostate: a prospective feasibility study and review of literature显示文摘 | Hemendra N.Shah Sunil S.Hegde Jignesh N.Shah Amol P.Mahajan Manish B.Bansal | 2007 | BJU International2007，，3： | 1 |
| 18 | Immediate endoscopic management of complete iatrogenic anterior urethral injuries:A case series with long-term results显示文摘 | Pankaj N Maheshwari Hemendra N Shah | 2005 | BMC Urology2005，5，： | 1 |
| 19 | Simultaneous transurethral cystolithoottipsy with holmium laser enudclation of the prostate:a prospective feasibility study and review of literature显示文摘 | SHAH SUNIL S | 2006 | BJU Int2006，9，： | 1 |
| 20 | Urinary tract infections and post-operative fever in percutaneous nephrolithotomy显示文摘 | Jorge Gutierrez Arthur Smith Petrisor Geavlete Hemendra Shah Ali Riza Kural Marco Sio José H. Amón Sesmero András Hoznek Jean Rosette | 2013 | World Journal of Urology2013，，5： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员