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279篇 您的检索式:作者名="Herskovits"
    题名 作者 年代 出处 被引量
1Sirtuin deacetylases in neurodegenerative diseases of aging显示文摘Sirtuin 酶是高度保存的蛋白质 deacetylases 的一个家庭为他们的活动取决于菸碱腺嘌 dinucleotide (NAD+) 。在哺乳动物有七 sirtuins,这些蛋白质被 modulating 精力新陈代谢, genomic 稳定性和压力抵抗与热量的限制和老化连接了。Sirtuin 酶是在包括癌症,糖尿病,煽动性的混乱和 neurodegenerative 疾病的许多人的疾病的潜在的治疗学的目标。sirtuin 活动的调整被显示了包括 Alzheimer 的疾病影响几形成总数的 neurodegenerative 混乱的功课, Parkinson 的疾病,亨廷顿的疾病, amyotrophic 侧面的硬化和针、球根的肌肉发达的萎缩。Sirtuins 能由 modulating 抄写因素活动并且直接影响 neurodegenerative 混乱的前进 deacetylating proteotoxic 种类。这里,我们在几形成总数的 neurodegenerative 疾病描述 sirtuin 蛋白质目标并且讨论在这些混乱调制 sirtuin 活动的混合物的治疗学的潜力。Adrianna Z Herskovits Leonard Guarente 2013Cell Research2013,23,6:13
2Memorandum on the study of acculturation显示文摘Redfield R Linton R Herskovits M J 1936American Anthropologist1936,,38:1
3A QP-free globally convergent, locally superlinearly convergent algorithm for inequality constained optimizaiton显示文摘Panier E R Tits A L Herskovits J N 1988SIAM Journal on Control and Optimization1988,26,:1
4Mathematical programming models and algorithms for engineering design optimization显示文摘J. Herskovits P. Mappa E. Goulart C.M. Mota Soares 2005Computer Methods in Applied Mechanics and Engineering2005,,30:1
5A Bayesian Method for the induction of Probabilistic Networks from data显示文摘Cooper G Herskovits E 1992Machine Learning (S0885-6125)1992,122,9:1
6A Bayesian method for the introduction of probabilistic networks from data显示文摘Gregory F Copper Edward Herskovits 1992Machine Learning1992,9,:1
7Development of a finite element model for the identification of mechanical and piezoelectric properties through gradient optimization and experimental vibration data显示文摘Araujo A L Mota Soares C M Herskovits J 2002Composite Structures2002,58,:1
8A bayesian method for the induction of probabilistic networks from data 显示文摘COOPER G F HERSKOVITS E 1992Machine Learning1992,9,4:1
9A two-stage feasible direction algorithm for nonlinear constrained opti- mization 显示文摘algorithm for mathematical programs with Applied Mathematics and Mechanics 2009 Herskovits J 1986Mathematical Programming1986,36,:1
10A Bayesian method for the induction of probabilistic networks from data 显示文摘COOPER HERSKOVITS 1992Machine Learning1992,9,4:1
11A Bayesian method for the induction of probabilistic networks from data 显示文摘 Herskovits E 1992Machine Learning1992,9,:1
12A Bayesian method for the induction of probabilistic networks from data显示文摘Cooper G Herskovits E 1992Machine Learning1992,9,:1
13Uterine fibroids:diffusion-weighted Mr imaging for monitoring therapywith focused ultrasound surgery- preliminary study显示文摘Jacobs MA Herskovits EH Kim HS 2005Radiology2005,236,1:1
14A Bayesian method for the induction of probabilistic networks from data 显示文摘Cooper G F Herskovits E 1992Machine Learn- ing1992,9,4:1
15On the computer implementation of feasible direction interior point algorithms for nonlinear optimization显示文摘Herskovits J Santos G 1997Structural Optimization1997,14,23:1
16A bayesian method for the induction of probabilistic networks from data显示文摘Cooper G Herskovits E 1992Machine Learning1992,,9:1
17A Bayesian method for the induction of probabilistic networks from data显示文摘Cooper G F Herskovits E 1992Machine Learning1992,9,:1
18A Bayesian Method for the Induction of Probabilistic Network Form Data显示文摘COOPER G HERSKOVITS E 1992Machine Learning1992,9,:1
19Shape structural optimization with an interior point nonlinear programming algorithm显示文摘Herskovits J Dias G Santos G 2000Structural and Multidisciplinary Optimization2000,20,2:1
20A Bayesian method for the induction of probabilistic networks from data 显示文摘Cooper C Herskovits E 1992Maching Learning1992,122,9:1
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