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| 1 | High-resolution multimodal flexible coherent Raman endoscope显示文摘Coherent Raman scattering microscopy is a fast,label-free,and chemically specific imaging technique that shows high potential for future in vivo optical histology.However,the imaging depth in tissues is limited to the sub-millimeter range because of absorption and scattering.Realization of coherent Raman imaging using a fiber endoscope system is a crucial step towards imaging deep inside living tissues and providing information that is inaccessible with current microscopy tools.Until now,the development of coherent Raman endoscopy has been hampered by several issues,mainly related to the fiber delivery of the excitation pulses and signal collection.Here,we present a flexible,compact,coherent Raman,and multimodal nonlinear endoscope(4.2mm outer diameter,71mm rigid length)based on a resonantly scanned hollow-core Kagomé-lattice double-clad fiber.The fiber design enables distortion-less,background-free delivery of femtosecond excitation pulses and back-collection of nonlinear signals through the same fiber.Sub-micrometer spatial resolution over a large field of view is obtained by combination of a miniature objective lens with a silica microsphere lens inserted into the fiber core.We demonstrate high-resolution,high-contrast coherent anti-Stokes Raman scattering,and second harmonic generation endoscopic imaging of biological tissues over a field of view of 320μm at a rate of 0.8 frames per second.These results pave the way for intraoperative label-free imaging applied to real-time histopathology diagnosis and surgery guidance. | Alberto Lombardini Vasyl Mytskaniuk Siddharth Sivankutty Esben Ravn Andresen Xueqin Chen Jérôme Wenger Marc Fabert Nicolas Joly Frédéric Louradour Alexandre Kudlinski Hervé Rigneault | 2018 | Light(Science & Applications)2018，7，1： | 6 |
| 2 | Intensified chemotherapy with ACVBP plus rituximab versus standard CHOP plus rituximab for the treatment of diffuse large B-cell lymphoma (LNH03-2B): an open-label randomised phase 3 trial显示文摘 | Christian Récher Bertrand Coiffier Corinne Haioun Thierry Jo Molina Christophe Fermé Olivier Casasnovas Catherine Thiéblemont André Bosly Guy Laurent Franck Morschhauser Hervé Ghesquières Fabrice Jardin Serge Bologna Christophe Fruchart Bernadette Corront | 2011 | 2011 (9806)2011，，9806： | 2 |
| 3 | CD20 is associated with a small mature plasma cell morphology and t(11;14) in multiple myeloma显示文摘 | Nelly R Herve AL Richard G | 2003 | Blood2003，102，3： | 1 |
| 4 | CT and MRI findings in primitive pituitary abscess: a case report and review of literature 显示文摘 | Sabbah P Bonardel G Herve R | 1999 | J Neuroradiol1999，26，3： | 1 |
| 5 | Finding drug targets in microbial genomes 显示文摘 | Timothy D R Steven R G Herve T | 2001 | Res Focus2001，6，17： | 1 |
| 6 | Glucose-6-phosphate isomerase is not a specific autosntigen in rheumatoid arthritis 显示文摘 | Herve CA Wait R Venables PJ | 2003 | Rheumatology ( Oxford )2003，42，3： | 1 |
| 7 | Visualisation of ectomycorrhizal rhizomorph structure using laser scanning confocal microscope显示文摘 | Peter F S Herve R Bengt S | 2002 | Mycological Research2002，106，3： | 1 |
| 8 | Improving artificial neural network with a pruning methodology and genetic algorithms for their application in microbial growth prediction in foods显示文摘 | García-Gimeno R M Hervás-Mátinez C De Siloniz I | 2002 | International Journal of Food Microbiology2002，72，： | 1 |
| 9 | Glucose-6-phosphate isomerase is not a specific autoantigen in rheumatoid arthritis 显示文摘 | Herve C A Wait R Venables P J | 2003 | Rheumatology2003，42，： | 1 |
| 10 | The Drosophila amidase PGRP-LB modulates the immune response to bacterial infection显示文摘 | Zaidman-Rémy A Hervé M Poidevin M Pili-Floury S Kim MS Blanot D Oh BH Ueda R Mengin-Lecreulx D Lemaitre B | | 0，，04： | 1 |
| 11 | Etude qualitative des solutions reells d'une equation differentielleliee a l'equation de Ginzburg-Landau显示文摘 | Herve R M Herve M | 1994 | Ann IHP Anal nonline1994，11，： | 1 |
| 12 | An artificial neural network approach to Escherichia Coli O157:H7 growth estimation显示文摘 | García-Gimeno R M Hervás-Martínez C Barco-Alcalá E | | 0，，： | 1 |
| 13 | Contamination performance of silicone rubber cable terminations part-2显示文摘 | Gorur R S Herving H C Johnson L A | 1991 | Transmission and Distribution Conference1991，22，： | 1 |
| 14 | Compact air-cooled heat sinks for power packages显示文摘 | ATTIAL Aranyosi LEON M R Bolle HERVE A Buyse | 1997 | IEEE Transaction on Component Packaging and Manufacturing Technology Part A1997，20，4： | 1 |
| 15 | An artificial neural network approach to Escherichia coli O157:H7 growth estimation显示文摘 | García-Gimeno R M Hervás-Martínez C Barco Alcalá E | 2003 | Journal of Food Science2003，68，2： | 1 |
| 16 | Current limitations about the cleaning of lu-minal endoscopes显示文摘 | Herve R Keevil CW | 2013 | J Hosp Infect2013，83，1： | 1 |
| 17 | Glucose-6-phosphate isomerase is not a specific autoantigen in rheumatoid arthritis显示文摘 | Herve CA Wait R Venables PJ | 2003 | Rheumatology:Oxford2003，42，8： | 1 |
| 18 | Adsorption of prion and tissue pro-teins to surgical stainless steel surfaces and the efficacy of decon-tamination following dry and wet storage conditions 显示文摘 | Seeker TJ Herve R Keevil CW | 2011 | J Hosp In-fect2011，78，4： | 1 |
| 19 | The PDE4 inhibitor rolipram prevents NF-kB binding activity and proinflammatory cytokine release in human chorionic cells显示文摘 | Herve R Schmitz T Evain-Brion D Cabrol D Leroy M J Mehats C | 2008 | J ImmunoI2008，181，： | 1 |
| 20 | Posttraumatic Pseudoaneurysm of the Hepatic Artery: Treatment with Ultrasound-Guided Percutaneous Transhepatic Thrombin Injection显示文摘 | Camille Dambrin Bertrand Marcheix Tudor Birsan Christophe Cron Fabrice Muscari Bertrand Suc Alain Cérène Hervé Rousseau | 2005 | The Journal of Trauma: Injury, Infection, and Critical Care2005，，1： | 1 |
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