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		题名	作者	年代	出处	被引量
	1	sTWEAK is a marker of early haematoma growth and leukoaraiosis in intracerebral haemorrhage显示文摘Objective To study the association between early growth of haematoma with biomarkers of endothelial dysfunction such as leukoaraiosis(LA)and the soluble tumour necrosis factor-like weak inducer of apoptosis(sTWEAK)in patients with intracerebral haemorrhage(ICH).Methods This is a retrospective observational study of patients with nontraumatic ICH.Clinical and biochemical parameters were analysed.sTWEAK levels were measured by ELISA.LA was analysed in the hemisphere without haemorrhage to avoid interference with the acute injury.The main endpoint was the haematoma growth evaluated by the difference in volume between the second and the initial neuroimage.Poor functional outcome,defined as a modified Rankin Scale>2 at 3 months,was considered as secondary endpoint.Receiver operating characteristic curve analysis was performed to stablish the best cut-off for sTWEAK levels associated with haematoma growth.Results We included 653 patients with ICH in our analysis(71.1±11.9 years,44%women).Haematoma growth was observed in 188 patients(28.8%).sTWEAK levels≥5600 pg/mL predicted ICH growth with a sensitivity of 84%and a specificity of 87%.sTWEAK levels≥5600 pg/mL and the presence of LA were associated with haematoma growth(OR:42.46;(CI 95%22.67 to 79.52)and OR:2.73(CI 95%1.39 to 5.34),respectively).Also,the presence of LA(OR:4.31(CI 95%2.89 to 6.42))and the interaction between ICH growth and sTWEAK(OR:2.23(CI 95%1.40 to 3.55))were associated with poor functional outcome at 3 months.Conclusion sTWEAKs,together with the presence and grade of LA,are biomarkers able to predict ICH growth and poor functional outcome in patients with ICH.	Andrés da Silva-Candal Iria López-Dequidt Manuel Rodriguez-Yañez PauloÁvila-Gómez JoséManuel Pumar JoséCastillo Tomás Sobrino Francisco Campos Ramón Iglesias-Rey Pablo Hervella	2021	Stroke & Vascular Neurology2021，6，4：	2
	2	The sixteen classes of almost Hermitian manifolds and their local invariants显示文摘	Gray A Hervella L M	1980	Ann Mat Pura Appl1980，123，1：	1
	3	Epidural analgesia in obstetrics: is there an effect on albor and delivery显示文摘	Segado Jimenez MI Arias Delgado J Dominguez Hervella F	2011	Rev Esp Anestesiol Reanim2011，58，1：	1
	4	The sixteen classes of almost Hermitian manifolds and their linear invariants显示文摘	Gray A Hervella L M	1980	Annali di Matematica Pura ed Applicata1980，123，：	1
	5	Toxicity of silver nanoparticles in macrophages 显示文摘	Pratsinis A Hervella P Leroux JC	2013	Small2013，9，15：	1
	6	An optimal perfectly matched layer with unbounded absorbing function for time - harmonic acoustic scattering problems 显示文摘	Bermudez L M Hervella - Nieto Prieto 3 Rodrtguez R	2007	Journal of Computational Physics2007，223，2：	1
	7	Clinical results of hallux valgus minimally surgery显示文摘	Barragan Hervella RG Morales Flores F Arratia Rios M		0，，03：	1

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