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| 1 | Phase angle obtained by bioelectrical impedance analysis independently predicts mortality in patients with cirrhosis显示文摘AIM To evaluate the prognostic value of the phase angle(PA)obtained from bioelectrical impedance analysis(BIA) for mortality prediction in patients with cirrhosis. METHODS In total, 134 male cirrhotic patients prospectively completed clinical evaluations and nutritional assessment by BIA to obtain PAs during a 36-mo follow-up period. Mortality risk was analyzed by applying the PA cutoff point recently proposed as a malnutrition marker(PA ≤ 4.9°) in Kaplan-Meier curves and multivariate Cox regression models. RESULTS The patients were divided into two groups according to the PA cutoff value(PA > 4.9°, n = 73; PA ≤ 4.9°, n = 61). Weight, height, and body mass index were similar in both groups, but patients with PAs > 4.9° were younger and had higher mid-arm muscle circumference, albumin, and handgrip-strength values and lower severe ascites and encephalopathy incidences, interleukin(IL)-6/IL-10 ratios and C-reactive protein levels than did patients with PAs ≤ 4.9°(P ≤ 0.05). Forty-eight(35.80%) patients died due to cirrhosis, with a median of 18 mo(interquartile range, 3.3-25.6 mo) follow-up until death. Thirty-one(64.60%) of these patients were from the PA ≤ 4.9° group. PA ≤ 4.9° significantly and independently affected the mortality model adjusted for Model for End-Stage Liver Disease score and age(hazard ratio = 2.05, 95%CI: 1.11-3.77, P = 0.021). In addition, Kaplan-Meier curves showed that patients with PAs ≤ 4.9° were significantly more likely to die. CONCLUSION In male patients with cirrhosis, the PA ≤ 4.9° cutoff was associated independently with mortality and identified patients with worse metabolic, nutritional, and disease progression profiles. The PA may be a useful and reliable bedside tool to evaluate prognosis in cirrhosis. | Giliane Belarmino Maria Cristina Gonzalez Raquel S Torrinhas Priscila Sala Wellington Andraus Luiz Augusto Carneiro D'Albuquerque Rosa Maria R Pereira Valéria F Caparbo Graziela R Ravacci Lucas Damiani Steven B Heymsfield Dan L Waitzberg | 2017 | World Journal of Hepatology2017，9，7： | 11 |
| 2 | Waist circumference and cardiometabolic risk:a consensus statement from shaping America's heahh:Association for Weight Management and Obesity Prevention ; NAASO,the Obesity Society ; the American Society for Nutrition ; and the American Diabetes Association显示文摘 | Klein S Allison DB Heymsfield SB | 2007 | Obesity (Silver Spring)2007，15，： | 1 |
| 3 | Human-body Composition and the Epidemiology of Chronic Disease显示文摘 | BAUMGARTNER R N HEYMSFIELD S B ROCHE A F | 1995 | Obes Res1995，3，： | 1 |
| 4 | Radar and radiation of ice Clouds显示文摘 | MATROSOV S Y HEYMSFIELD A J | 1995 | J Appl Meteor1995，34，： | 1 |
| 5 | Dual en- ergy X-Ray absorptiometry body composition reference values from NHANES 显示文摘 | KELLY T L WILSON K E HEYMSFIELD S B | 2009 | PLoS ONE2009，4，9： | 1 |
| 6 | Human-body Composition and the Epidemiology of Chronic Disease显示文摘 | Baumgartner R N Heymsfield S B Roche A F | 1995 | Obes Res1995，，3： | 1 |
| 7 | Abdominal composition quantified by computed tomography 显示文摘 | Baumgartner R N Heymsfield S B Roche A F | 1988 | Am J Clin Nutr1988，48，： | 1 |
| 8 | Race-ethniei- ty-specific waist circumference cutoffs for identifying cardio- vascular disease risk factors 显示文摘 | Zhu S Heymsfield SB Toyoshima H etal | 2005 | Am J Clin Nutr2005，81，2： | 1 |
| 9 | Weight management using a meal replacement strategy: meta and pooling analysis from six studies 显示文摘 | HEYMSFIELD S B van MIERLO C A van der KNAAP H C | 2003 | Int J Obes Relat Metab Disord2003，27，5： | 1 |
| 10 | Waist circumference and cardiometabolic risk: a consensus statement from shaping America's health: Association for Weight Management and Obesity Prevention ; NAASO, the Obesity Society; the American Society for Nutrition; and American Diabetes Association 显示文摘 | Klein S Allison DB Heymsfield SB | 2007 | Diabetes Care2007，30，6： | 1 |
| 11 | Effect of calcium supplementation on weight and fat loss in women 显示文摘 | Shapses SA Heshka S Heymsfield SB | 2004 | J Clin Endocrinol Metab2004，89，2： | 1 |
| 12 | Modeling of Sub-millimeter Passive Remote Sensing of Cirrus Cloud 显示文摘 | Evans K F Walter S J Heymsfield A J | 1998 | Journal of Applied Meteorology1998，37，： | 1 |
| 13 | Waist circumference and cardiometabolic risk:a consensus statement from shaping America's health:association for weight management and obesity prevention;NAA- SO,the Obesity Society;the American Society for Nutrition;and the American Diabetes Association显示文摘 | Klein S Allison DB Heymsfield SB | 2007 | Diabetes Care2007，30，6： | 1 |
| 14 | Waist circumference and abdominal adipose tissue distribution: influence of age and sex 显示文摘 | Kuk JL Lee S Heymsfield SB | 2005 | Am J Clin Nutr2005，81，： | 1 |
| 15 | Race-ethnicity-specific waist circumference cutoffs for identifying cardiovascular disease risk factors显示文摘 | Zhu S Heymsfield SB Toyoshima H | 2005 | Am J Clin Nutr2005，81，2： | 1 |
| 16 | Aerosol indirect effects as a function of cloud top pressure 显示文摘 | Massie S T Heymsfield A Schmitt C | 2007 | Journal of Geophysical Research2007，112，： | 1 |
| 17 | Recombinant leptin for weight loss in obese and lean adults:a randomized,controlled,dose-escalation trial显示文摘 | Heymsfield I S | | 0，，： | 1 |
| 18 | Accurate measurement of liver,kinding and spleen volume and mass by computerited axial tomography显示文摘 | Heymsfield S Fulonnicler T Nerdingler B | 1979 | Ann Intern Med1979，90，2： | 1 |
| 19 | Menopausal Changes in Body Composition and Energy Expenditure显示文摘 | HEYMSFIELD S B GALLAGHER D POEHLMAN E T | 1994 | Exp Gerontol1994，29，： | 1 |
| 20 | Waist circumference and cardiometabolic risk a consensus statement from shaping America' s Health: association for weight management and obesity prevention ; NAASO, The obesity society; the American society for nutrition ; and the American Diabetes 显示文摘 | Klein S Allison DB Heymsfield SB | 2007 | Obesity2007，15，5： | 1 |
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