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| 1 | Phytochemical analysis and antioxidants activities of aqueous stem bark extract of Schotia latifolia Jacq显示文摘Objective:To evaluate the phytochemical constituents and antioxidant activities of aqueous extract of Scholia latifolia(S.latifolia)bark locally used for the treatment of oxidative stress-induced ailments in South Africa.Methods:The antioxidant and free radical scavenging activity of aqueous extract of the plant was assessed against 1,1-diphenyl-2-pierylhydrazyl(DPPH),nitric oxide(NO),2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonic acid)diammonium salt(ABTS)and the ferric reducing agent.Total phenolics,flavonoids,flavonols and proanthocyanidins were also determined to assess their corresponding effect on the antioxidant activity of this plant.Results:The activities of plant extract against DPPH,ABTS and NO radicals were concentration dependent with IC_(50)value of 0.06,0.05 and 0.05 mg/mL,respectively.The reducing power of the extract was greater than that of butylated hydroxyl toluene(BHT)and ascorbic acid which were used as standard drugs in a concentration dependent manner.The total phenolics content of the aqueous bark extract was(193.33±0.03 TE/g),followed by flavonoids(72.70±0.01 QE/g),proanthocyanidins|48.76±0.00 CE/g)and flavonols(47.76±0.21 QE/g).Phytochemical analysis revealed the presence of percentage tannin(11.40±0.02),alkaloid(9.80±0.01),steroids(18.20±0.01),glycosides(29.80±0.01)and saponins(6.80±0.00).The results exhibited a positive linear correlation between these polyphenols and the free radical scavenging activities.Conclusions:Our findings provide evidence that the crude aqueous extract of S.latifolia is a potential source of natural antioxidants and this justifies its uses in folkloric medicines. | Mbaebie BO Edeoga HO Afolayan AJ | 2012 | Asian Pacific Journal of Tropical Biomedicine2012，2，2： | 15 |
| 2 | 职业健康监护评价与死亡相关的队列研究显示文摘目的 探讨广州市职业健康监护评价结果与死亡的相关性。方法 利用 1989~ 1992年广州市实施职业健康监护 (OHS)系统中建立的 399家工厂中≥ 35岁的 78785名职工的个体健康档案为基础资料 ,按前瞻性队列研究方法 ,随访至 1998年 12月 31日 ,了解队列中职工的生存状态和死亡情况 ,并进行 χ2 检验和Cox模型分析。结果 (1)队列中 78785名职工随访 8年 ,共 6 2 76 35人年(男性 3892 40人年 ) ,总死亡人数为 15 2 5人 ,总死亡率为 2 43.0 / 10万人年 (男 330 .4/ 10万人年、女10 0 .3/ 10万人年 )。 (2 )队列中男女职工有职业接触史者分别为 46 .1%和 34.4% ,建档时有吸烟史男女职工分别占 70 .3%和 1.5 %。 (3)无论男性或女性 ,总死亡率与OHS评价结果均有明显相关 ,调整年龄、文化程度、吸烟与职业接触等因素后 ,评价为追踪观察或异常者与评价为健康或大致健康者比较 ,其相对危险度 (RR)分别为男 :1.85 (95 %CI为 1.5 8~ 2 .18)和 2 .71(95 %CI为 2 .39~ 3.0 8) ,女 :1.80 (95 %CI为 1.2 2~ 2 .6 4)和 2 .89(95 %CI为 2 .17~ 3.86 ) ;进一步分析肿瘤、心脑血管疾病等主要死因死亡率与OHS评价结果间的相关性 ,结果与上述相似。 (4 )男性中年组 (35~ 49岁 )OHS评价为追踪观察或异常者 ,心脑血管疾病? | 江朝强 Lam TH 刘薇薇 张维森 Ho SY 何健民 AJ Hedley | 2000 | 中华劳动卫生职业病杂志2000，18，6： | 6 |
| 3 | 职业有害因素接触或(和)吸烟对死亡的影响——广州165660名职工队列的前瞻性研究显示文摘目的 研究职业有害因素接触或 (和 )吸烟对死亡的影响。方法 利用 1989~ 1992年广州市实施职业健康监护系统建立的 16 5 6 6 0名年龄≥ 30岁的工厂职工和司机的个体健康档案为基础资料 ,填入光学扫描直读表 (ICR)并建立基线数据库 ,随访至 1998年 12月 31日 ,了解队列中职工生存状态和死亡原因 ,计算RR(95 %CI) ,绘制产生职业有害因素接触或吸烟的累积生存曲线。结果 (1)16 5 6 6 0名队列职工 ,平均年龄 (4 2 .0± 6 .3)岁 ,30~ 49岁占 87% ;37.3%的职工接触职业有害因素 ,工厂男职工吸烟率为 70 .8% ,男司机吸烟率为 5 4.8% ,全部女职工吸烟率不足 2 .0 % ;(2 )平均随访时间为 (7.6± 1.1)年 ,共随访 12 5 2 16 8人年 ,总死亡人数为 2 437人 ,有 5 1名死因不明 (占 2 .1% ) ,总死亡率为 194.6 /10万人年 ;(3)调整相关因素后 ,职业有害因素接触对总死亡、中风和其他原因的死亡 ,其RR(95 %CI)分别为 1.11(1.0 2~ 1.2 0 )、1.30 (1.0 1~ 1.6 8)和 1.2 7(1.0 6~ 1.5 1) ;吸烟对男职工总死亡、恶性肿瘤和肺癌死亡 ,其RR(95 %CI)分别为 1.2 3(1.11~ 1.35 )、1.34 (1.16~ 1.5 4)和 2 .5 1(1.81~3.48) ;职业有害因素接触并吸烟者 ,总死亡和恶性肿瘤死亡的RR(95 %CI)增至 1.32 (1.16~ 1.5 1)和1. | 江朝强 Lam TH 刘薇薇 张维森 Ho SY AJ Hedley 何健民 曹民 朱昌淇 | 2001 | 中华劳动卫生职业病杂志2001，19，5： | 6 |
| 4 | 抑郁治疗和急性心肌梗死后1年死亡率的相关性:TRIUMPH注册研究显示文摘在急性心肌梗死(acute myocardial infarction,AMI)患者中,抑郁症是很普遍的,并且与不良的生活质量和预后相关。尽管一些国家组织提出了筛选抑郁症的建议,但尚不清楚AMI患者的抗抑郁治疗是否与更好的预后相关。该研究的目的是确定接受抗抑郁治疗是否对患者的预后有影响。方法: | 刘莉 叶鹏 Smolderen KG Buchanan DM Gosch K Whooley MA Chan PS Vaccarino V Parashar S Shah AJ Ho PM Spertus JA | 2017 | 中华高血压杂志2017，25，2： | 2 |
| 5 | Contrasting effects of oral and transdermal routes of estrogen replacement therapy on 24-hour growth factor (GH) secretion,insulin-like growth factor I,and GH-binding protein in postmenopausal women显示文摘 | Weissberger AJ Ho KY Lazarus L | 1991 | J Clin Endocrinol Metab1991，72，2： | 1 |
| 6 | Repeatability characteristics of simple indices of insulin resistance :implications for research applications 显示文摘 | Mather KJ Hunt AJ Steinberg HO | 2001 | J ClinEndocrinol Metab2001，86，： | 1 |
| 7 | Cardiac resynchronization therapy in patients with right bundle branch block : analysis of pooled data from the MIRACLE and Contak CD trials 显示文摘 | Egovail CA Ho RT Greenspon AJ | 2005 | Heart Rhythm2005，2，6： | 1 |
| 8 | Synapsin I is a highly surface-active molecule显示文摘 | HO MF BIHLER M CZERNIK AJ | 1991 | J Biol Chem1991，266，9： | 1 |
| 9 | Profile of tumor anti gen-specific CD8 T cells in patients with hepatitis B virus-re- lated hepatocellular carcinoma显示文摘 | Gehring AJ Ho ZZ Tan AT | 2009 | Gastroenterology2009，137，： | 1 |
| 10 | A 40-year history of overweight children in Stockholm : life-time overweight, morbidity,and mortality显示文摘 | Dipietro L Mossberg HO Stunkard AJ | 1994 | Int J Obes Relat Metab Disord1994，18，9： | 1 |
| 11 | Repeatability characteristics of simple indices of insulin resistance : implications for research applications 显示文摘 | Mather KJ Hunt AJ Steinberg HO | 2001 | Clin Endoerinol Metab2001，86，： | 1 |
| 12 | IMRT dose fractionation for head and neck cancer:variation in current approaches will make standardisation difficult显示文摘 | Ho KF Fowler JF Sykes AJ | | 0，，03： | 1 |
| 13 | Prevention ofpufnonaiy hpertension by angintensiir converting enzyne 2 gene-transfer显示文摘 | YanazatoY Ferreira AJ Hong Kworr Ho | 2009 | Hypertension2009，54，2： | 1 |
| 14 | Engineering virus-specific T cells that target HBV infected hepatocytes and hepatocellular carcinoma cell lines显示文摘 | Gehring AJ Xue SA Ho ZZ | | 0，，01： | 1 |
| 15 | Antiviral effect of epigalloeatechin gallate on enterovirus 71显示文摘 | Ho HY Cheng ML Weng SF et aJ | 2009 | Ag''ic and Food Chem2009，57，： | 1 |
| 16 | Disposition of cocaine in blood and brain after a single pretreatanent显示文摘 | Pettit HO Pettit AJ | 1994 | Brain Res1994，651，1： | 1 |
| 17 | The use of the index of orthodontic treatment need in dental primary care显示文摘 | Ho AJ Crawford F Clarkson J | 2009 | Br Dent J2009，206，8： | 1 |
| 18 | Mortality and smoking in Hongkong:case-control study of all adult deaths in 1998显示文摘 | Lam TH Ho SY Hedley AJ | 2001 | BMJ2001，323，7309： | 1 |
| 19 | Repeatability characteristics of simple indices of insulin resistance:implications for research applications显示文摘 | Mather KJ Hunt AJ Steinberg HO | 2001 | J Clin Endocrinol Metab2001，86，11： | 1 |
| 20 | Temporal expression of and matrix molecules in healing tendon lesions显示文摘 | Dahlgren LA Mohammed HO Nixon AJ | 2005 | J Orthop Res2005，23，1： | 1 |
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