|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Screening and identification of mimotopes of the major shrimp allergen tropomyosin using one-bead-one- compound peptide libraries显示文摘one-bead-one-compound (OBOC ) 组合的肽图书馆是一个强大的工具识别 ligand 和受体相互作用。这里,我们使用了 OBOC 图书馆技术识别对主要贝壳变应原 tropomyosin 的免疫球蛋白 E (IgE ) epitopes 特定的 mimotopes。有 8-12 氨基酸残余的 OBOC 肽图书馆为 tropomyosin 的 IgE mimotopes 与贝壳过敏症从病人与浆液样品被屏蔽。25 mimotopes 从屏蔽被识别,他们到 tropomyosin 特定的 IgE 的有约束力的反应被肽 ELISA 证实。这些 mimotopes 能基于顺序相同被划分成七簇,并且由聚类的 mimotopes 的 EpiSearch 印射的 epitope 被执行描绘并且证实 mimotopes 的有效性。五从六预言的 epitopes 被发现与 tropomyosin 的以前识别的 epitopes 重叠。为了推进,证实 mimotopes 的模仿潜力, BALB/c 老鼠被使免疫, mimotopes 结合了到锁眼恋栈者 hemocyanin 和 assayed 让他们的能力导致 tropomyosin 特定的抗体。那收到的 mimotope 免疫被发现有 tropomyosin 特定的免疫球蛋白 G 的提高的水平的 BALB/c 老鼠,然而并非收到了无关的 mimotope 的老鼠。这研究用整个 sera 开创 OBOC 图书馆的成功的申请屏蔽并且识别多重虾变应原 mimotopes 并且验证他们在 vitro 使用的模仿潜力,在 vivo,并且在 silico 方法。 | Nicki YH Leung Christine YY Wai Marco HK Ho Ruiwu Liu Kit S Lam Jin Jun Wang Shang An Shu Ka Hou Chu Patrick SC Leung | 2017 | Cellular & Molecular Immunology2017，14，3： | 6 |
| 2 | Seroprevalence of antibodies to human herpes viruses in England and Hong Kong 显示文摘 | Kangro HO Osman HK | 1994 | J Med Virol1994，43，： | 1 |
| 3 | Direct toxicity effects of sulfo-conjugated trogUtazone on human hepatocytes 显示文摘 | Saha S New LS Ho HK Chui WK Chan EC | 2010 | Toxicol Lett2010，195，23： | 1 |
| 4 | Leakage after resection and intraperitoneal anastomosis for coloreclal malignancy: analysis of risk faetors显示文摘 | Choi HK Law WL Ho JW | 2006 | Dis Colon Rectum2006，49，11： | 1 |
| 5 | Involvement ofβ37 integrin and mucosal addressin cell adhesion molecule-1 (MAdCAM-1) in the development of diabetes in nonobese diabetic mice显示文摘 | Yang X Sytwn HK MeDevitt HO | 1997 | Diabetes1997，46，10： | 1 |
| 6 | A Case of Fibroelastolytic Papulosis on the Neck of a Young Man显示文摘 | Young CS Byung HO Jong HK | 2011 | Ann Dermatol2011，23，2： | 1 |
| 7 | ADMA regulates angiogenesis:genetic and metabolic evidence显示文摘 | Achan V Ho HK Heeschen C | 2005 | Vasc Med2005，10，1： | 1 |
| 8 | Reducing the induction to abortion interval in termination of second trimester comparison of mifepristone with laminaria tent显示文摘 | Ho PC Tsang SS Ma HK | 1995 | Br J Obstet Gynecol1995，102，8： | 1 |
| 9 | Salvia miltiorrhiza reduces experimentally-induced hepatic fibrosis in rats显示文摘 | Wasser S Ho JM Ang HK | 1998 | Journal of Hepatology1998，29，： | 1 |
| 10 | YC - 1 inhibits proliferation of human vascular endothelial cells through a cyclic GMP - independent pathway显示文摘 | Hsu HK Juan SH Ho PY | 2003 | Biochem Pharmacol2003，66，： | 1 |
| 11 | Synergistic impact of acute kidney injury and high level of cervical spinal cord injury on the weaning outcome ofpatients with acute traumatic cervical spinal cord injury显示文摘 | Yu WK Ko HK Ho LI | 2015 | Injury2015，46，7： | 1 |
| 12 | Development of a broad toxicological screening technique for urine using ultra- performance liquid chromatography and time-of-flight mass spectrometry显示文摘 | Lee HK Ho CS Iu YP et d | 2009 | Anal Chim Acta2009，649，1： | 1 |
| 13 | Leakage after resection and intraperitoneal anastomosis for colorcctal malignancy analysis of risk factors显示文摘 | Choi HK Law WL Ho JW | 2006 | Dis Colon Rectum2006，49，： | 1 |
| 14 | Synergistic impact of acute kidney injury and high level of cervical spinal cord injury on the weaning outcome of patients with acute traumatic cervical spinal cord injury 显示文摘 | Yu WK Ko HK Ho LI | 2015 | Injury2015，46，7： | 1 |
| 15 | Microbiological, epidemiological, and clinical characteristics and outcomes of patients with cryptococcosis in taiwan, 1997 -20 10 显示文摘 | Tseng HK Liu CP Ho MW | 2013 | PLoS One2013，8，61： | 1 |
| 16 | Intraocular pressure and ocular pulse amplitude compari-sons in different types of glaucoma using dynamic contour to-nometry显示文摘 | Punjabi OS Ho HK Kniestedt C Bostrom AG Stamper RL Lin SC | 2006 | Curr Eye Res2006，31，10： | 1 |
| 17 | Leakage after resection and intrap- eritoneal anastomosis for colorectal malignancy: analysis of risk factors 显示文摘 | Choi HK Law WL Ho JW | 2006 | Dis Colon Rectum2006，49，： | 1 |
| 18 | Salvia miitiorrhiza reduces experimentally induced hepatic fibrosis inrats显示文摘 | Wasser S Ho JM Ang HK | 1998 | J Hepatol1998，29，5： | 1 |
| 19 | Numerical taxonomic study of the nuts of genus Trapa in Korea显示文摘 | Ho CY Choi HK Su HKH | 1987 | Kor J Plant Tax1987，17，1： | 1 |
| 20 | Childhood acute dissemi- nated encephalomyelitis: the role of brain and spinal cord MRI 显示文摘 | Khong PL HK HO Cheng PW | 2002 | Pediatric Radiol2002，32，1： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员