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9篇 您的检索式:作者名="Hongbo H"
    题名 作者 年代 出处 被引量
1Robust H∞ exponential filtering for uncertain stochastic time-delay systems with Markovian switching and nonlinearities显示文摘YAN Huaicheng Max Q H Meng ZHANG Hao SHI Hongbo 0,,:1
2Programmable immune activating electrospun fibers for skin regeneration显示文摘Immune cells play a crucial regulatory role in inflammatory phase and proliferative phase during skin healing.How to programmatically activate sequential immune responses is the key for scarless skin regeneration.In this study,an“Inner-Outer”IL-10-loaded electrospun fiber with cascade release behavior was constructed.During the inflammatory phase,the electrospun fiber released a lower concentration of IL-10 within the wound,inhibiting excessive recruitment of inflammatory cells and polarizing macrophages into anti-inflammatory phenotype“M2c”to suppress excessive inflammation response.During the proliferative phase,a higher concentration of IL-10 released by the fiber and the anti-fibrotic cytokines secreted by polarized“M2c”directly acted on dermal fibroblasts to simultaneously inhibit extracellular matrix overdeposition and promote fibroblast migration.The“Inner-Outer”IL-10-loaded electrospun fiber programmatically activated the sequential immune responses during wound healing and led to scarless skin regeneration,which is a promising immunomodulatory biomaterial with great potential for promoting complete tissue regeneration.Lu Chen Liucheng Zhang Hongbo Zhang Xiaoming Sun Dan Liu Jianming Zhang Yuguang Zhang Liying Cheng Hélder A.Santos Wenguo Cui 2021Bioactive Materials2021,6,10:1
3Mussel-Inspired and Bioclickable Peptide Engineered Surface to Combat Thrombosis and Infection显示文摘Thrombosis and infections are the two major complications associated with extracorporeal circuits and indwelling medical devices,leading to significant mortality in clinic.To address this issue,here,we report a biomimetic surface engineering strategy by the integration of mussel-inspired adhesive peptide,with bio-orthogonal click chemistry,to tailor the surface functionalities of tubing and catheters.Inspired by mussel adhesive foot protein,a bioclickable peptide mimic(DOPA)4-azidebased structure is designed and grafted on an aminated tubing robustly based on catechol-amine chemistry.Then,the dibenzylcyclooctyne(DBCO)modified nitric oxide generating species of 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid(DOTA)chelated copper ions and the DBCO-modified antimicrobial peptide(DBCO-AMP)are clicked onto the grafted surfaces via bio-orthogonal reaction.The combination of the robustly grafted AMP and Cu-DOTA endows the modified tubing with durable antimicrobial properties and ability in long-term catalytically generating NO from endogenous snitrosothiols to resist adhesion/activation of platelets,thus preventing the formation of thrombosis.Overall,this biomimetic surface engineering technology provides a promising solution for multicomponent surface functionalization and the surface bioengineering of biomedical devices with enhanced clinical performance.Xiaohui Mou Hongbo Zhang Hua Qiu Wentai Zhang Ying Wang Kaiqin Xiong Nan Huang Hélder A.Santos Zhilu Yang 2022Research2022,,3:1
4Akt as a mediator of cell death显示文摘Hongbo RL Hidenori H Mir AH 2003PNAS2003,100,11:1
5Polyan- iline stabilized magnetite nanoparticle reinforced epoxy nanocomposites显示文摘HONGBO C- SRUTHI T YUDONG H 2012ACS Application Materials and Interfaces2012,4,10:1
6Genetic algorithms for construction site layout in project planning显示文摘Mawdesley Saad H A Hongbo M J 2002Journal of Construction Engineering and Management2002,128,5:1
7Variation for stomatal characteristics and water use efficiency among diploid,tetraploid and hexa-ploid Iranian wheat landraces显示文摘Khazaei H Monneveux P Hongbo S 2010Genetic Resources and Crop Evolution2010,57,2:1
8The roles of ERK1/2 and p38 MAP kinases in the preventive mechanisms of mushroom Phellinus linteus against the inhibition of gap junctional intercellular communication by hydrogen peroxides 显示文摘Jong H C Sung D C Hongbo H 2002Carcinogenesis2002,23,7:1
9Morphology and properties of compatibilized polylactide/thermoplastic starch blends 显示文摘Michel A H Li Hongbo 2007Polymer2007,48,:1
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