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| 1 | Amniotic fluid-derived stem cells mixed with platelet rich plasma for restoration of rat alveolar bone defect显示文摘从羊膜的液体孤立的干细胞作为房间治疗和织物工程的一个有希望的候选人被显示出。然而, maxillofacial 骨头织物工程的地里的羊膜的导出液体的干细胞(AFSC ) 的试验性、现出症状之前的潜的应用仍然是有限的。在这研究,老鼠 AFSC 成功地在 vitro 被收获并且描绘。老鼠 AFSC 显示出典型 fibroblastoid 形态学,稳定的增长活动和多区别潜力。Flow-cytometry 分析为象 CD34 和 CD45 那样的造血的标记证明这些房间为 CD29, CD44,和 CD90 是积极的,当否定时。与血小板富人一起的 AFSCs-premixed 的再生表演在牙槽的骨头缺点的恢复的血浆(PRP ) 胶化进一步用一只修改老鼠被调查颚的牙槽的缺点模型。微型电脑断层摄影术和组织学的检查在操作与控制组作比较以后在 4 和 8 个星期与 PRP 胶化显示出 AFSCs-premixed 的一个优异再生能力。而且,植入的 AFSC 能在缺点地点幸存并且直接参予骨头织物新生。一起拿,这些结果为牙槽的缺点恢复显示了基于 AFSCs 的牙槽的骨头织物工程策略的可行性。 | Minjiao Wang Hongliang Li Jiawen Si Jiewen Dai Jun Shi Xudong Wang Lihe Guo Guofang Shen | 2017 | Acta Biochimica et Biophysica Sinica2017，49，3： | 5 |
| 2 | Cellulose nanofiber separator for suppressing shuttle effect and Li dendrite formation in lithium-sulfur batteries显示文摘Lithium-sulfur battery(LSB) has high energy density but is limited by the polysulfides shuttle and dendrite growth during cycling. Herein, a free-standing cellulose nanofiber(CNF) separator is designed and fabricated in isopropanol/water suspension through vacuum filtration progress. CNFs with abundant polar oxygen-containing functional groups can chemically immobilize the polysulfides, and suppress the formation of the dendrites by controlling the surface morphology of the SEI on lithium metal in LSB. The isopropanol content in a suspension can fine-tune the pore structure of the membrane to achieve optimal electrochemical performance. The prepared separator displays integrated advantages of an ultrathin thickness(19 μm), lightweight(0.87 mg cm^(-2)), extremely high porosity(98.05%), and decent electrolyte affinity. As a result, the discharge capacity of the LSB with CNF separator at the first and 100 th cycle is 1.4 and 1.3 times that of PP separator, respectively. Our research provides an environmentalfriendly and facile strategy for the preparation of multifunctional separators for LSBs. | Jingxue Li Liqin Dai Zhefan Wang Hao Wang Lijing Xie Jingpeng Chen Chong Yan Hong Yuan Hongliang Wang Chengmeng Chen | 2022 | Journal of Energy Chemistry2022，31，4： | 4 |
| 3 | Development of upland rice introgression lines and identification of QTLs for basal root thickness under different water regimes显示文摘基因渗入线(IL ) 是为识别量的特点 loci (QTL ) 的珍贵材料,评估帮助的基因相互作用,和标记繁殖。包含的一套 430 IL (BC5F3 ) 在一块低地从高地分割热带装饰用的梨树栽培变种 IRAT109 适度的装饰用的梨树栽培变种 Yuefu 背景被开发。176 个多态的标记被用来识别 introgressed 片断。从 IRAT109 的片断都没在 160 根线被发现。另外的 270 根线的 Introgressed 片断盖住 99.1% 施主染色体。introgressed 施主片断的吝啬的数字与 14.4 厘米的平均长度每个人是 3.3。QTL 分析在在灌溉低地,高地和水耕法的条件下面种的 270 IL 的基础根厚度(BRT ) 上被进行。影响 BRT 的 22 QTL 的一个总数被识别,六 QTL (qBRT3.1, qBRT3.2, qBRT6.1, qBRT8.2, qBRT9.1,和 qBRT9.2 ) 一致地在至少二环境(地点和水政体) 下面被表示,并且 qBRT7.2 是在低地条件下面识别的新 BRT QTL。包含 qBRT9.1 的 IL255 在栽培变种 Yuefu 上看了 10.09% 和 7.07% BRT 的增加什么时候分别地在高地和低地条件下面成长。用 304 根 F2:3 线的一张人口源于生气 IL255 ??????? 瑡歭?? 匠 ? 彋 ????????? 僚 ?? 传敶敲灸敲獳潩吗?? | Junzhou Li Deping Wang Yan Xie Hongliang Zhang Guanglong Hu Jinjie Li Anyong Dai Lifeng Liu Zichao Li | 2011 | Journal of Genetics and Genomics2011，38，11： | 3 |
| 4 | A novel PIK3CD C896T mutation detected in bilateral sudden sensorineural hearing loss using next generation sequencing:An indication of primary immunodeficiency显示文摘Objective: To investigate immune-related genetic background in bilateral sudden sensorineural hearing loss(SSNHL).Case report and methods: The case is a 45-year-old man presenting with a 7-year history of bilateral profound SSNHL. Blood biochemical testing demonstrated increased levels of total cholesterol(5.88 mmol/L). Tests for hepatitis B showed a positive antibody against the hepatitis B core antigen. Complement C3 was below the normal value, and complement C4 and Ig G were in the lower range of normal values. CT images showed a normal inner ear and vestibular aqueduct but round window membranous ossification on both sides. A total number of 232 immuneassociated genes were sequenced using the next generation sequencing technique.Results: Mutations were detected in 5 genes, including the phosphoinositide 3-kinase catalytic subunit delta(PIK3CD), caspase recruitment domain-containing protein 9(CARD9), complement factor H-related(CFHR2), immunoglobulin lambda-like polypeptide 1 Protein(IGLL1),and transmembrane channel-like gene family 8(TMC8). In the PIK3 CD gene, a C896 T substitute in exon 7 was detected. This mutation causes primary immunodeficiency and is an autosomal dominant disease.Conclusion: The PIK3 CD C896T mutation responsible for primary immunodeficiency may contribute to the onset of bilateral SSNHL with subsequent rapid progression. | Jing Zou Xiangqiang Duan Guiliang Zheng Zhen Zhao Shiyue Chen Pu Dai Hongliang Zheng | 2016 | Journal of Otology2016，11，2： | 3 |
| 5 | Isoflurane-induced neuronal apoptosis in developing hippocampal neurons显示文摘We hypothesized that the P2X7 receptor may be the target of isoflurane, so we investigated the roles of the P2X7 receptor and inositol triphosphate receptor in calcium overload and neuronal apoptosis induced by isoflurane in cultured embryonic rat hippocampal neurons. Results showed that isoflurane induced widespread neuronal apoptosis and significantly increased cytoplasmic Ca 2+ . Blockade of P2X7 receptors or removal of extracellular Ca 2+ combined with blockade of inositol triphosphate receptors completely inhibited apoptosis or increase in cytoplasmic Ca 2+ . Removal of extracellular Ca 2+ or blockade of inositol triphosphate receptor alone could partly inhibit these effects of isoflurane. Isoflurane could directly activate P2X7-gated channels and induce inward currents, but did not affect the expression of P2X7 receptor protein in neurons. These findings indicate that the mechanism by which isoflurane induced neuronal apoptosis in rat developing brain was mediated by intracellular calcium overload, which was caused by P2X7 receptor mediated calcium influx and inositol triphosphate receptor mediated calcium release. | Hongliang Liu Tijun Dai Weitao Guo | 2013 | Neural Regeneration Research2013，8，9： | 2 |
| 6 | Structural damage de- tection using the combination method of EMD and wavelet analy- sis显示文摘 | Helong Li Xiaoyan Deng Hongliang Dai | 2007 | Mechanical Systems and Signal Processing2007，，21： | 1 |
| 7 | Maternal genetic history of ancient Tibetans over the past 4000 years显示文摘The settlement of the Tibetan Plateau epitomizes human adaptation to a high-altitude environment that poses great challenges to human activity.Here,we reconstruct a 4000-year maternal genetic history of Tibetans using 128 ancient mitochondrial genome data from 37 sites in Tibet.The phylogeny of haplotypes M9a1a,M9a1b,D4g2,G2a’c,and D4i show that ancient Tibetans share the most recent common ancestor with ancient Middle and Upper Yellow River populations around the Early and Middle Holocene.In addition,the connections between Tibetans and Northeastern Asians vary over the past 4000 years,with a stronger matrilineal connection between the two during 4000 BPe3000 BP,and a weakened connection after 3000 BP,that are coincident with climate change,followed by a reinforced connection after the Tubo period(1400 BPe1100 BP).Besides,an over 4000-year matrilineal continuity is observed in some of the maternal lineages.We also find the maternal genetic structure of ancient Tibetans is correlated to the geography and interactions between ancient Tibetans and ancient Nepal and Pakistan populations.Overall,the maternal genetic history of Tibetans can be characterized as a long-term matrilineal continuity with frequent internal and external population interactions that are dynamically shaped by geography,climate changes,as well as historical events. | Ganyu Zhang Can Cui Shargan Wangdue Hongliang Lu Honghai Chen Lin Xi Wei He Haibing Yuan Tinley Tsring Zujun Chen Feng Yang Tashi Tsering Shuai Li Norbu Tashi Tsho Yang Yan Tong Xiaohong Wu Linhui Li Yuanhong He Peng Cao Qingyan Dai Feng Liu Xiaotian Feng Tianyi Wang Ruowei Yang Wanjing Ping Ming Zhang Xing Gao Yichen Liu Wenjun Wang Qiaomei Fu | 2023 | Journal of Genetics and Genomics2023，50，10： | 1 |
| 8 | Astragalus polysaccharide inhibits isoprenaline-induced cardiac hypertrophy via suppressing Ca 2+ -mediated calcineurin/NFATc3 and CaMKII signaling cascades显示文摘 | Hongliang Dai Guizhi Jia Xin Liu Zhining Liu Hongxin Wang | 2014 | Environmental Toxicology and Pharmacology2014，，1： | 1 |
| 9 | Structural Damage Detection Using the Combination Method of EMD and Wavelet Analysis 显示文摘 | Li Helong Deng Xiaoyan Dai Hongliang | 2007 | Mechanical Systems and Signal Processing2007，21，： | 1 |
| 10 | Influence of cerium precursors on the structure and reducibility of mesoporous CuO-CeO 2 catalysts for CO oxidation显示文摘 | Lei Qi Qiang Yu Yue Dai Changjin Tang Lianjun Liu Hongliang Zhang Fei Gao Lin Dong Yi Chen | 2012 | Applied Catalysis B Environmental2012，，： | 1 |
| 11 | Exact solutions for functionally graded pressure vessels in a uniform magnetic field 显示文摘 | DAI Hongliang FU Yiming DONG Zhiming | 2006 | International Journal of Solids and Structures2006，43，1819： | 1 |
| 12 | Structural damage detection using the combination method of EMD and wavelet analysis 显示文摘 | Li Helong Deng Xiaoyan Dai Hongliang | 2007 | Mechanical Systems and Signal Processing2007，21，： | 1 |
| 13 | Structural damage detection using the combination method of EMD and wavelet analysis 显示文摘 | Li Helong Deng Xiaoyan Dai Hongliang | 2007 | Mechanical Systems and Signal Processing2007，21，： | 1 |
| 14 | Analytical solutions of stresses in functionally graded piezoelectric hollow structures显示文摘 | Dai Hongliang Xiao Xia Fu Yiming | 2010 | Solid State Communications2010，150，1516： | 1 |
| 15 | Cell type-specific proteomics uncovers a RAF15-SnRK2.6/OST1 kinase cascade in guard cells显示文摘Multicellular organisms such as plants contain various cell types with specialized functions.Analyzing the characteristics of each cell type reveals specific cell functions and enhances our understanding of organization and function at the organismal level.Guard cells(GCs)are specialized epidermal cells that regulate the movement of the stomata and gaseous exchange,and provide a model genetic system for analyzing cell fate,signaling,and function.Several proteomics analyses of GC are available,but these are limited in depth.Here we used enzymatic isolation and flow cytometry to enrich GC and mesophyll cell protoplasts and perform in-depth proteomics in these two major cell types in Arabidopsis leaves.We identified approximately 3,000 proteins not previously found in the GC proteome and more than600 proteins that may be specific to GC.The depth of our proteomics enabled us to uncover a guard cell-specific kinase cascade whereby Raf15and Snf1-related kinase2.6(SnRK2.6)/OST1(open stomata 1)mediate abscisic acid(ABA)-induced stomatal closure.RAF15 directly phosphorylated SnRK2.6/OST1 at the conserved Ser175 residue in its activation loop and was sufficient to reactivate the inactive form of SnRK2.6/OST1.ABAtriggered SnRK2.6/OST1 activation and stomatal closure was impaired in raf15 mutants.We also showed enrichment of enzymes and flavone metabolism in GC,and consistent,dramatic accumulation of flavone metabolites.Our study answers the long-standing question of how ABA activates SnRK2.6/OST1 in GCs and represents a resource potentially providing further insights into the molecular basis of GC and mesophyll cell development,metabolism,structure,and function. | Hongliang Wang Yubei Wang Tian Sang Zhen Lin Rongxia Li Weiwei Ren Xin Shen Bing Zhao Xiao Wang Xuebin Zhang Shaoqun Zhou Shaojun Dai Honghong Hu Chun-Peng Song Pengcheng Wang | 2023 | Journal of Integrative Plant Biology2023，65，9： | 0 |
| 16 | Effect of brain-derived neurotropic factor released from hypoxic astrocytes on gamma-aminobutyric acid type A receptor function in normal hippocampal neurons显示文摘Astrocytes can release increased levels of brain-derived neurotrophic factor during cerebral ischemia, but it is unclear whether brain-derived neurotrophic factor affects γ-aminobutyric acid type A receptor function in normal neurons. Results from this study demonstrated that γ-aminobutyric acid at 100 μmol/L concentration raised the intracellular calcium level in neurons treated with medium from cultured hypoxic astrocytes, and the rise in calcium level could be inhibited by γ-aminobutyric acid type A receptor antagonist bicuculline or brain-derived neurotrophic factor receptor antagonist k252a. γ-aminobutyric acid type A-gated current induced by 100 μmol/L γ-aminobutyric acid was in an inward direction in physiological conditions, but shifted to the outward direction in neurons when treated with the medium from cultured hypoxic astrocytes, and this effect could be inhibited by k252a. The reverse potential was shifted leftward to -93 mV, which could be inhibited by k252a and Na+-K+-Cl- cotransporter inhibitor bumetanide. Brain-derived neurotrophic factor was released from hypoxic astrocytes at a high level. It shifted the reverse potential of γ-aminobutyric acid type A-gated currents leftward in normal neurons by enhancing the function of Na+-K+-Cl- cotransporter, and caused γ-aminobutyric acid to exert an excitatory effect by activating γ-aminobutyric acid type A receptor. | Hongliang Liu Tijun Dai | 2011 | Neural Regeneration Research2011，6，25： | 0 |
| 17 | Non-uniform Compressive Sensing Imaging Based on Image Saliency显示文摘For more effective image sampling,compressive sensing(CS) imaging methods based on image saliency have been proposed in recent years.Those methods assign higher measurement rates to salient regions,but lower measurement rate to non-salient regions to improve the performance of CS imaging.However,those methods are block-based,which are difficult to apply to actual CS sampling,as each photodiode should strictly correspond to a block of the scene.In our work,we propose a non-uniform CS imaging method based on image saliency,which assigns higher measurement density to salient regions and lower density to non-salient regions,where measurement density is the number of pixels measured in a unit size.As the dimension of the signal is reduced,the quality of reconstructed image will be improved theoretically,which is confirmed by our experiments.Since the scene is sampled as a whole,our method can be easily applied to actual CS sampling.To verify the feasibility of our approach,we design and implement a hardware sampling system,which can apply our non-uniform sampling method to obtain measurements and reconstruct the images.To our best knowledge,this is the first CS hardware sampling system based on image saliency. | LI Hongliang DAI Feng ZHAO Qiang MA Yike CAO Juan ZHANG Yongdong | 2023 | Chinese Journal of Electronics2023，32，1： | 0 |
| 18 | MECHANICAL AND ACOUSTIC RESPONSE OF AN UNDERWATER STRUCTURE SUBJECTED TO MECHANICAL EXCITATION显示文摘In this paper, an underwater structure is modeled as a cylindrical shell with internal bulkheads, and closed by a truncated conical shell, and it consists of metal substrate and sound absorbing coating, whose FGM core is considered. Suppose the inner cavity and outer space of the structure are filled with air and fluid mediums, the mechanical response of the underwater structure is calculated with Galerkin method while the acoustic response is investigated by means of the Helmholtz integral. Some numerical examples are given and the effect of geometrical size and material parameters on mechanical and acoustic response is discussed. | Xuetao Weng Shijian Zhu Hongliang Dai Yiming Fu Yiqi Mao | 2014 | Acta Mechanica Solida Sinica2014，27，3： | 0 |
| 19 | Mathematical modeling for of arctigenin from acidultrasonic-assisted extractionhydrolyzed FructusArctii显示文摘A mathematical model based on Fick' s first law wasestablished to describe the process of ultrasonic-assistedextraction of arctigenin from acid hydrolyzed FructusArctii.Acid hydrolization with hydrochloric acid promotes theconversion of arctiin to arctigenin in the arctiin-rich activepharmaceutical ingredient, and the hydrolyzed products werefurther examined to investigate the process setup. Byconsidering the mechanism of the extraction process andexperimental data, the effects of parameters including solventto solid ratio, particle size of hydrolyzed samples, ethanolvolume fraction, ultrasound power, extraction temperature andextraction time on concentration of arctigenin were analyzed indetail. The model was suitable for simulating the process ofultrasonic-assisted extraction of arctigenin. The simulationresults of the model agree well with experimental data with thedeviation below 13%, indicating that the mathematical modelcan provide valuable guidance for the extraction of arctigeninfrom acid hydrolyzed FructusArctii. | Dai Lin Zhang Yong Hu Chi Qian Hongliang Wang Zhixiang | 2017 | Journal of Southeast University(English Edition)2017，33，3： | 0 |
| 20 | Study of MRPC technology for BESIII endcap-TOF upgrade显示文摘Purpose In order to improve the charged particle identi-fication capability,end-cap time-of-flight(ETOF)detector of the Beijing Spectrometer(BESIII)has been upgraded with multi-gap resistive plate chamber(MRPC)technology,aiming at an overall time resolution of 80 ps for minimum-ionization particles to extend the K/πseparation(2σ)momentum range to 1.4 GeV/c.Methods The previous version of ETOF in BESIII consisted of plastic scintillators.The multi-hit events distort both shape and amplitude of the output signals.MRPC technique was chosen for the BESIII ETOF upgrade as it provides high time resolution and high detection efficiency,is of relatively low cost and is insensitive to neutral particles.Most importantly,the fine segmentation of the MRPC readout stripes can suppress multi-hit events effectively.Results The final design of MRPC module for ETOF is characterized by double-stack(2×6)structure,dual-end readout mode and precision electronics.To batch-produce and test these MRPC modules,a series of tools and production procedures as well as related performance simulation and test methods were developed.Results showed that each MRPC module’s intrinsic time resolution(including the electronics contribution)is around 50 ps and the efficiency is better than 97%.The overall performance of the upgraded ETOF is better than the designed index.The new ETOF has been successfully installed at BESIII and run in 2016. | Xin Li Yongjie Sun Cheng Li Zhen Liu Yuekun Heng Ming Shao Xiaozhuang Wang Zhi Wu Ping Cao Mingming Chen Hongliang Dai Shubing Liu Xiaolan Luo Xiaoshan Jiang Shengsen Sun Zebo Tang Weijia Sun Siyu Wang Meihang Xu Rongxing Yang Kejun Zhu | 2017 | Radiation Detection Technology and Methods2017，1，2： | 0 |
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