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| 1 | Three-dimensional ordered macroporous platinum-based electrode for methanol oxidation显示文摘In this paper, three-dimensional ordered macroporous platinum catalysts with high real sur- face area were synthesized using the inverted col- loidal crystals template technique and have been employed for the electrooxidation of methanol. The morphology and electrocatalytic behavior of the po- rous Pt electrodes were investigated with atomic force microscopy and electrochemical techniques. For the same amount of Pt deposited, the real sur- face areas of the electrodes are 9.16 and 8.00 cm2 for the porous electrodes with pore size of 320 and 500 nm respectively, which are more than 5 times larger than the directly deposited Pt electrode (1.4 cm2). The pore size effect on the methanol elec- trooxidation was investigated by testing low concen- tration solution of methanol and porous materials with different pore sizes. The synthesized macroporous Pt electrode shows high stability toward the electrooxi- dation of methanol and is promising for the direct methanol fuel cell. | ZHANG Dai GAO Wei XIA Xinghua CHEN Hongyuan | 2006 | Chinese Science Bulletin2006，51，1： | 2 |
| 2 | Some Analysis in Distributed MIM0 Systems显示文摘 | Dai Huaiyu Zhang Hongyuan Zhou Quan | 2007 | Journal of Communication2007，24，3： | 1 |
| 3 | Compact electro-optic modulator on lithium niobate显示文摘Fast electro-optic modulators with an ultracompact footprint and low power consumption are always highly desired for optical interconnects.Here we propose and demonstrate a high-performance lithium niobate electro-optic modulator based on a new 2×2 Fabry–Perot cavity.In this structure,the input and reflected beams are separated by introducing asymmetric multimode-waveguide gratings,enabling TE_(0)−TE_(1)mode conversion.The measured results indicate that the fabricated modulator features a low excess loss of∼0.9dB,a high extinction ratio of∼21dB,a compact footprint of∼2120μm^(2),and high modulation speeds of 40 Gbps OOK and 80 Gbps PAM4 signals.The demonstrated modulator is promising for high-speed data transmission and signal processing. | Bingcheng Pan Hongyuan Cao Yishu Huang Zong Wang Kaixuan Chen Huan Li Zejie Yu Daoxin Dai | 2022 | Photonics Research2022，10，3： | 1 |
| 4 | Mesoporous materials promoting direct electrochemistry and electrocatalysis of horseradish peroxidase显示文摘 | DAI Zhihui JU Huangxian CHEN Hongyuan | 2005 | Electroanalysis2005，17，： | 1 |
| 5 | Co-channel interference mitigation and cooperative processing in downlink multicell multiuser MIMO networks 显示文摘 | ZHANG Hongyuan DAI Huaiyu | 2004 | EURASIP Journal on Wireless Communications and Networking2004，，22： | 1 |
| 6 | Coehannel Interference Mitigation and Cooperative Processing in Downlink Muhi-cell Muhiuser MIMO Networks 显示文摘 | ZHANG Hongyuan DAI Huaiyu | 2004 | EURASIP Journal on Wireless Communications and Networking2004，2004，2： | 1 |
| 7 | Experimental Study on Z-Pin Bridging Law by Pullout Test 显示文摘 | Dai Shaocong Yah Wenyi Liu Hongyuan | 2004 | Composites Science and Technology2004，64，： | 1 |
| 8 | On the Diversity Order of Spatial Multiplexing Systems with Transmit Antenna Selection: A Geometrical Approach 显示文摘 | ZHANG Hongyuan DAI Huaiyu ZHOU Quan | 2006 | IEEE Trans on Information Theory2006，52，12： | 1 |
| 9 | Fast MIMO Transmit Antenna Selection Algorithms: A Geometric Approach 显示文摘 | Hongyuan Zhang Huaiyu Dai | 2006 | IEEE Communications Letters (S1089-7798)2006，10，11： | 1 |
| 10 | Cochannel interference mitiga- tion and cooperative processing in downlink multicell multi- user MIMO networks 显示文摘 | Zhang Hongyuan Dai huaiyu | 2004 | EURASIP Journal on Wireless Communications and Networking2004，，2： | 1 |
| 11 | Cochannel Interference Mitigation and Cooperative Processing in Downlink Multicell Multiuser M IMO Networks显示文摘 | ZHANG Hongyuan DAI huaiyu | 2004 | Eurasip Journal on Wireless Communications and Networking2004，，2： | 1 |
| 12 | Experimental study on Z-pin bridging law by pullout test显示文摘 | Dai Shaocong Yan Wenyi Liu Hongyuan Mai Yiu- Wing | 2004 | Composites Science and Technology2004，64，16： | 1 |
| 13 | Experimental study on z-pin bridging law by pullout test显示文摘 | Dai Shaocong Yan Wenyi Liu Hongyuan | 2004 | Composites Science and Technology2004，64，16： | 1 |
| 14 | Degradation of FAK-targeting by proteolytic targeting chimera technology to inhibit the metastasis of hepatocellular carcinoma显示文摘Liver cancer is a prevalent malignant cancer,ranking third in terms of mortality rate.Metastasis and recurrence primarily contribute to the high mortality rate of liver cancer.Hepatocellular carcinoma(HCC)has low expression of focal adhesion kinase(FAK),which increases the risk of metastasis and recurrence.Nevertheless,the efficacy of FAK phosphorylation inhibitors is currently limited.Thus,investigating the mechanisms by which FAK affects HCC metastasis to develop targeted therapies for FAK may present a novel strategy to inhibit HCC metastasis.This study examined the correlation between FAK expression and the prognosis of HCC.Additionally,we explored the impact of FAK degradation on HCC metastasis through wound healing experiments,transwell invasion experiments,and a xenograft tumor model.The expression of proteins related to epithelial-mesenchymal transition(EMT)was measured to elucidate the underlying mechanisms.The results showed that FAK PROTAC can degrade FAK,inhibit the migration and invasion of HCC cells in vitro,and notably decrease the lung metastasis of HCC in vivo.Increased expression of E-cadherin and decreased expression of vimentin indicated that EMT was inhibited.Consequently,degradation of FAK through FAK PROTAC effectively suppressed liver cancer metastasis,holding significant clinical implications for treating liver cancer and developing innovative anti-neoplastic drugs. | XINFENG ZHANG SHUANG LI MEIRU SONG YUE CHEN LIANGZHENG CHANG ZHERUI LIU HONGYUAN DAI YUTAO WANG GANGQI YANG YUN JIANG YINYING LU | 2024 | Oncology Research2024，32，4： | 0 |
| 15 | Real-time analysis of inflammatory cytokines and regulatory gene expression in tissues surrounding the hematoma after intracerebral hemorrhage显示文摘BACKGROUND:Secondary lesions can occur in tissues surrounding the hematoma following intracerebral hemorrhage,with the presence of inflammatory reactions,cytokine expression and apoptosis. These have been confirmed in animal studies. Our study sought to determine whether these could be detected in human tissues surrounding the hematoma following intracerebral hemorrhage. OBJECTIVE: To investigate expression of inflammatory cytokines,Bax and Bcl-x,and identify neural cell apoptosis in tissues surrounding the hematoma,and to analyze the correlation between them and pathological damage in intracerebral hemorrhage patients. DESIGN,TIME AND SETTING: This histopathology,controlled study was performed at the Department of Neurosurgery,Sichuan People’s Hospital,China,from January 2003 to January 2005. PARTICIPANTS: Brain tissues 1 cm from the hematoma in 30 intracerebral hemorrhage patients served as the experimental group. Brain tissues located away from the hematoma in 7 patients served as the control group. METHODS: TUNEL was used to detect neural cell apoptosis. Immunohistochemistry (labeled dextran polymer) and RT-PCR were used to measure tumor necrosis factor-α,interleukin-1β,interleukin-6,Bax and Bcl-x protein and mRNA expression. Pathological changes in brain tissues surrounding the hematoma were observed following HE staining. MAIN OUTCOME MEASURES: Neural cell apoptosis,inflammatory cytokines,Bax and Bcl-x protein and mRNA expression,pathological changes in brain tissues surrounding the hematoma. RESULTS: Brain tissues surrounding the hematoma were mildly damaged within 6 hours,severely damaged at 24-72 hours,and significantly improved 1 week following intracerebral hemorrhage. Expression of tumor necrosis factor-α protein and mRNA,interleukin-1β and interleukin-6 mRNA was not significant in tissues surrounding the hematoma,which was identical to the control group within 6 hours after intracerebral hemorrhage. This expression was significantly higher compared with the control group from 12-72 hours,and gradually decreased after 72 hours. The number of apoptotic neural cells reached a peak between 12-72 hours. Tumor necrosis factor-α protein and mRNA,interleukin-1β and interleukin-6 mRNA levels were positively correlated with apoptosis,Bax protein and mRNA levels (P<0.01). CONCLUSION: Tumor necrosis factor-α,interleukin-1β,and interleukin-6 levels are highly correlated with apoptosis. With the decrease in tumor necrosis factor-α,interleukin-1β and interleukin-6 levels,the number of apoptotic cells gradually reduced. | Longyi Chen Fuqiang Guo Xiaojia Li Hong Yang Yousong Yang Hongyuan Dai Yongsheng Wei Yulan Huang Hongbin Sun Yuchuan Xu Zhenglin Yang | 2008 | Neural Regeneration Research2008，3，11： | 0 |
| 16 | Waveguide-integrated optical modulators with two-dimensional materials显示文摘Waveguide-integrated optical modulators are indispensable for on-chip optical interconnects and optical computing.To cope with the ever-increasing amount of data being generated and consumed,ultrafast waveguide-integrated optical modulators with low energy consumption are highly demanded.In recent years,two-dimensional(2D)materials have attracted a lot of attention and have provided tremendous opportunities for the development of high-performance waveguide-integrated optical modulators because of their extraordinary optoelectronic properties and versatile compatibility.This paper reviews the state-of-the-art waveguide-integrated optical modulators with 2D materials,providing researchers with the developing trends in the field and allowing them to identify existing challenges and promising potential solutions.First,the concept and fundamental mechanisms of optical modulation with 2D materials are summarized.Second,a review of waveguide-integrated optical modulators employing electro-optic,all-optic,and thermo-optic effects is provided.Finally,the challenges and perspectives of waveguide-integrated modulators with 2D materials are discussed. | Haitao Chen Hongyuan Cao Zejie Yu Weike Zhao Daoxin Dai | 2023 | Journal of Semiconductors2023，44，11： | 0 |
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