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	题名	作者	年代	出处	被引量
1	脑缺血后N-myc下游调控基因2保护血脑屏障完整性显示文摘脑缺血后血脑屏障(BBB)的破坏与外周细胞向脑内浸润、病孔损形成与进展、以及临床病程恶化密切相关。目前BBB完整性的调控机制,尤其是在永久性缺血后的调控机制尚未明确。本研究使用小鼠永久性脑缺血模型进行相关研究,结果显示,星形胶质细胞N-myc下游调控基因2(NDRG2)可能是缺血性脑卒中后BBB通透性的调控分子,该分子与分化和应激相关。免疫组化显示,在永久性大脑中动脉闭塞(MCAO)后,NDRG2在星形胶质细胞中的表达显著增加。敲除NDRG2基因,脑梗死体积增加,免疫细胞在缺血同侧大脑半球积聚增加。MCAO后,NDRG2基因敲除小鼠缺血侧皮质的缺血灶内及灶周血管周围区域内的血清蛋白(包括纤维蛋白原和免疫球蛋白)的外渗增强此之,MCAO后NDRG2基因敲除小鼠体内基质金属蛋白酶(MMPs)的表达也显著增加。在细胞培养中,NDRG2-/-星形胶质细胞中MMP-3的表达和分泌增加,这种增加可被腺病毒介导的NDRG2再表达所逆转。综上所述,脑缺血后,星形胶质细胞内的NDRG2可能通过调节MMP的表达,而在BBB通透性的调节和免疫细胞浸润中起到重要作用。	Takarada-Iemata M Yoshikawa A Ta HM Okitani N Nishiuchi T Aida Y Kamide T Hattori T Ishii H Tamatani T Le TM Roboon J Kitao Y Matsuyama T Nakada M Hori O 聂昊	2018	神经损伤与功能重建2018，13，4：	4
2	FTIR measurements of charge displacement adsorption of CO on poly-and single crystal (100) of Cu electrodes显示文摘	Koga O Watanabe Y	1998	Electrochimica Acta1998，44，：	1
3	A multiple Lyapunov function approach to stabilization of fuzzy control systems 显示文摘	TANAKA K HORI T WANG H O	2003	IEEE Transactions on Fuzzy Systems2003，11，4：	1
4	Formation of formic acid and organic peroxides in the ozonolysis of ethene with added water vapor 显示文摘	Horie O Neeb P Limbach S	1994	Geophysical Research Letters1994，21，：	1
5	MicroRNA-33b knock-in mice for an intron of sterol regulatory element-binding factor 1 (Srebf1) exhibit reduced HDL-C in vivo显示文摘	Horie T Nishino T Baba O	2014	Sci Rep2014，4，：	1
6	Electrocatalytic process of CO selectivity in electrochemical reduction of CO2 at metal electrodes in aqueous media 显示文摘	Hori Y Wakebe H Tsukamoto T Koga O	1994	Electrochimica Acta1994，39，1112：	1
7	MicroRNA-451 exacerbates lipotoxicity in cardiac myocytes and high-fat diet- induced cardiac hypertrophy in mice through suppression of the LKB1/AMPK pathway显示文摘	KUWABARA Y HORIE T BABA O	2015	Circ Res2015，116，2：	1
8	Association between the neutrophil myeloperoxidase index and subsets of bacterial infections显示文摘	Yonezawa K Horie O Yoshioka A	2010	Int J Lab Hematol2010，32，62：	1
9	Relative effectiveness and interaction of ultraviolet-B, red and blue light in anthocyanin synthesis of apple fruit 显示文摘	ARAKAWA O HORI Y OGATA R	1985	Physiologia Plantarum1985，64，3：	1
10	Automated impedance matching system for robust wireless power transfer via magnetic resonance coupling 显示文摘	BEH T C KATO M IMURA T SEHOON O HORI Y	2013	IEEE Transactions on Industrial Electronics2013，60，9：	1
11	Role of protein kinase C and transcriptionfactor AP-1 in the acid-induced increase in Na+/H+ antiporter activity显示文摘	Moe O Yamaji Y	1992	Proc Natl Acad Sci USA1992，89，12：	1
12	Cellular stress responses: cell survival and cell death显示文摘	Fulda S Gorman AM Hori O	2010	Int J Cell Biol2010，2010，21：	1
13	Characteristics of color devel opment and relationship between anthoc-yanin synthesis and phenylalanine ammonia lyase activity in 'Starking Deli- cious','Fuji' and 'Mut su'apple fruits显示文摘	Arakawa O Hori Y Ogata R	1986	J Jpn Soc Hort Sci1986，54，：	1
14	Expression of 1502kd oxygen-regulated protein in the hippocampus suppresses delayed neuronal cell death显示文摘	Miyazaki M Ozawa K Hori O	2002	J Cereb Blood Flow Metab2002，22，8：	1
15	Role of Protein kinase C and transcription factor AP-1 in the acid-induced increase in Na/H antiporter activity显示文摘	Horie S Moe O Yamaji Y	1992	Proc Natl Acad Sci USA1992，89，12：	1
16	Seasonal variation of the bacterial flora in coastal sea- water in relation to occurrence of Vibrio parahaemolyticus显示文摘	Shin S U S Horie O Okuzumi	1976	Bull Jap Soc Scient Fish1976，42，：	1
17	Elevated Plasma Levels of Vascular Cell Adhesion Molecule-1 (VCAM-1) in Diabetic Patients with Micro-albumin of Urine: a Marker of Vascular Dysfunction and Progressive Vascular is Ease显示文摘	Schmidt A M Crandall J Hori O	1996	Br J H aematol1996，92，3：	1
18	Advanced glycation endproducts interacting with their endothelial receptor induce expression of vascular cell adhesion molecule-1 in cultured human endothelial cells and in mice显示文摘	Schmidt AM Hori O Chen JX	1995	J Clin Invest1995，96，3：	1
19	A multiple Lyapunov function approach to stabilization of fuzzy control systems 显示文摘	TANAKA K HORI T WANG H O	2003	IEEE Trans on Fuzzy Systems2003，11，4：	1
20	Annotation-based Web Content Transcoding显示文摘	Hori M Kondoh G Kouichi O	2000	Computer Networks2000，33，1：	1

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