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| 1 | A new numerical method to solve modified Reynolds equation for magnetic head/disk working in ultra-thin gas films显示文摘The modified Reynolds equation for ultra-thin gas films between magnetic head and disk assembly is difficult to solve with conventional numerical methods, since the bearing number is very large and there exist boundary layers where pressure changes rapidly. An iterative finite difference algorithm is introduced to solve the nonlinear modified Reynolds equation, with special treatment for the abrupt change in the thickness of the gas film. The numerical results for two types of magnetic heads demonstrate that the scheme is effective. | Howard H HU | 2008 | Science China(Technological Sciences)2008，51，4： | 7 |
| 2 | SEASONAL CIRCULATION IN THE NORTHWESTERN TROPICAL PACIFIC OCEAN DIAGNOSED WITH THE ASSIMILATION DATA FROM 1989 THROUGH 1997显示文摘An assimilation data set based on the Geophysical Fluid Dynamics Laboratory (GFDL) Modular Ocean Model version 3 (MOM3) and the NODC XBT data set is used to examine the circulation and its variabilities in the western tropical Pacific, with special emphasis on the seasonal variations. It is shown that the assimilated and observed mean velocities and transports of the major flows in the western tropical Pacific agree well. The flows in the north Pacific, including the North Equatorial Current (NEC), Kuroshio, Mindanao Current (MC) and North Equatorial Countercurrent (NECC) west of 140°E display the seasonal cycles almost in the same phase, with the biggest transport in spring and the smallest in autumn. The phase of the NECC seasonal cycle east of 140°E is opposite to that in the west. Besides of the annual cycle, there seems to be a semi annual fluctuation of the NECC transport possibly resulting from the phase lag between seasonal cycles of the NEC and NGCC. Strong in summer during the southeast monsoon, the seasonal cycle of the Indonesian Throughflow (ITF) is closely linked with those of both the MC and the New Guinea Coastal Current/Undercurrent (NGCC/NGCUC), but not as strong as that in observations probably caused by the superimposed seasonal and interannual variations. Variations on the interannual time scale are also discussed, but only indistinct interannual variations of the flows related to the ENSO are revealed during 1989~1997. Transport of the NEC, Kuroshio and NECC are slightly larger in the E1 Nino years when that of the ITF is weaker, while the MC has little ENSO related variation. There were also quasi biennial signals superimposing the ENSO like oscillations in the flows, but their relationships with the ENSO are still unclear. | Wang, Fan Chang, Ping Hu, Dun-Xin Howard, Seidel | 2001 | Journal of Hydrodynamics2001，13，3： | 5 |
| 3 | A novel mutation of WT1 exon 9 in a patient with Denys-Drash syndrome and pyloric stenosis 显示文摘 | Hu M Craig J Howard N | 2004 | Pediatr Nephrol2004，19，10： | 1 |
| 4 | Natural history of moderate aplastic anemia in children显示文摘 | HOWARD S C NAIDU P E HU X J | 2004 | Pediatr Blood Cancer2004，43，5： | 1 |
| 5 | Natural history of moderate aplastic anemia in children显示文摘 | Howard SC Naidu PE Hu X J | 2004 | Pediatr Blood Cancer2004，43，5： | 1 |
| 6 | numerical simulation of electroosmotic flow显示文摘 | Neelesh A Patanka r Howard H Hu | 1998 | Anal Chem1998，70，： | 1 |
| 7 | Natural history of moder- ate aplastic anemia in children 显示文摘 | Howard SC Naidu PE Hu X J | 2004 | Pediatr Blood Cancer2004，43，： | 1 |
| 8 | Direct simulation of fluid particle motions显示文摘 | Howard H. Hu Daniel D. Joseph Marcel J. Crochet | 1992 | Theoretical and Computational Fluid Dynamics1992，，5： | 1 |
| 9 | Natural history of moderate aplastic anemia in children 显示文摘 | Howard SC Naidu PE Hu XJ | 2004 | Pediatr Blood Cancer2004，43，5： | 1 |
| 10 | In vitro generated ThI7 cells support the expansion and phenotypic stability of CD4+ Foxp3+ regulatory T cells in vivo显示文摘 | Zhou Q Hu Y Howard OM | 2014 | Cytokine2014，65，1： | 1 |
| 11 | Natural history of moderate aplastic anemia in children显示文摘 | Howard SC Naidu PE Hu XJ | 2004 | Pediatr Blood Cancer2004，43，： | 1 |
| 12 | Autonomous Ascent Abort Planning Applied to Military and Civilian Space Launch Vehicles显示文摘 | Mark C Jackson and Howard Hu | 2004 | AIAA 2004 - 65862004，，： | 1 |
| 13 | Reactiveion etching of LiNbO3显示文摘 | JACKEL J L HOWARD R E HU E L | 1981 | Appl Phys Lett1981，38，11： | 1 |
| 14 | The role of intrinsic and extrinsic polarity in generating reorientation illusions显示文摘 | Hu G Howard IP | 1999 | Investigative Opthalmology and Visual Science1999，，： | 1 |
| 15 | Natural history, of moderate aplastic anmnia in children显示文摘 | Howard SC Naidu PE Hu X J | 2004 | Pediatr Blood Cancer2004，43，： | 1 |
| 16 | Visually inducd reorientation illusions显示文摘 | Howard IP Hu G | 2001 | Perception2001，30，5： | 1 |
| 17 | 美国成年人环境镉和铅暴露与听力损失显示文摘[背景]虽然镉和铅在动物模型中是听力损失的已知危险因素,但在普通人群中仅有少量的镉和铅与听力相关性的流行病学研究。[目的]研究当控制噪声和其他主要导致听力损失的危险因素后,美国普通人群中血镉和铅暴露与听力损失的相关性。[方法]分析来自3698名20~69岁的美国成年人数据,他们被随机分配入国家健康和营养检查调查(NHANES)听力检测组(1999-2004)。计算听力阈值在频率为0.5、1、2和4kHz时的纯音平均值(PTA),并定义听力损失为任一耳PTA〉25dB。[结果]血镉和血铅的加权几何均数分别为0.40[95%可信区间(CI):0.39~0.42]μg/L和15.4(95%CI:14.9~16.0)μg/L。校正社会人口学、临床危险因素以及职业和非职业性噪声暴露后,血镉和铅浓度位于最高五分位数的人与最低五分位数的人相比,PTA分别增加13.8%(95%CI:4.6%~23.8%)和18.6%(95%CI:7.4%~31.1%)(P趋势〈0.05)。[结论]在美国普通人群中低浓度镉和铅暴露可能是听力损失的重要危险因素。这一发现支持要努力减少环境镉和铅暴露。 | Yoon-Hyeong Choi Howard Hu Bhramar Mukherjee Josef Miller Sung Kyun Park | 2013 | 环境与职业医学2013，30，2： | 1 |
| 18 | Natural history of moderate aplastic anemia in children显示文摘 | Howard SC Naidu PE Hu XJ | 2004 | Pediatr Blood Cancer2004，43，5： | 1 |
| 19 | Evidence from ^(18)O feeding studies for hydroxyl group donor in the reaction catalyzed by cytidylate hydroxymethylase MilA显示文摘5-Hydroxymethylcytosine (5hmC) was present in T-even phage and mammalian DNA. 5hmC in phage is formed by hydroxymethylation of the cytosine base in deoxycytidylate (dCMP) by deoxycytidylate hydroxymethylase (CH), which uses the solvent water as the hydroxyl group donor. By contrast, 5hmC is formed in mammal zygotes by the oxidation of 5-methylcytosine (5mC). 5hmC was also present in a nucleoside antibiotic mildiomycin and its formation is governed by a cytidylate hydroxymethylase MilA. However, the catalytic mechanism remains unknown. In the present study, we purified His-tagged MilA and fed its in vitro reaction with H218O. The LC-MS analysis of the product revealed that 18O was incorporated into the hydroxymethylated CMP (HmCMP), and the secondary MS result of 18O-labeled HmCMP indicated that 18O was incorporated into the cytosine of HmCMP. The results demonstrate that MilA uses solvent water as the hydroxyl group donor like CH. Moreover, Thr102 of MilA was predicted as potential critical amino acid anchoring one molecule of water for hydroxylation. Finally, organizational context comparison in microbial genomes reveals that six homologous ORFs originally annotated as putative thymidylate synthase (TS) are more likely to be CMP hydroxymethylase. | CHEN Cheng GAO TuLing ZHAO Gong DENG ZiXin HU ShenCai XU H Howard HE XinYi | 2013 | Chinese Science Bulletin2013，58，8： | 1 |
| 20 | Theδ-aminolevulinic acid dehydratase (ALAD) polymorphism and bone and blood levels in community-exposed men:the normative aging study显示文摘 | Hu Howard Wu MT Cheng YW | 2001 | Environ Health Perspect2001，109，8： | 1 |
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