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8篇 您的检索式:作者名="Hu Zuowei"
    题名 作者 年代 出处 被引量
1Evolution of strontium isotopic composition of sea-water from Late Permian to Early Triassic based on study of marine carbonates,Zhongliang Mountain,Chongqing,China显示文摘Collected from a Late Permian to Early Triassic sedimentary section in the Zhongliang Mountain of Chongqing, Southwest China, sixty marine carbonate samples were measured for the 87Sr/86Sr ratios, and corresponding evolution curve was constructed. The concentrations of SiO2, CaO, MgO, Mn and Sr are used to evaluate reservation of strontium isotopic composition for original seawater and the credi-bility of the dissolution method for sample preparation. The results show that most of the samples (except seven samples with the Mn/Sr ratios higher than 2) contain the original geochemistry signa-tures of ancient seawater. Compared to the published 87Sr/86Sr ratios from the Late Permian to Early Triassic, our database reported here is the largest and the curve constructed is the most complete. The strontium isotopic curve from Late Permian to Early Triassic is consistent globally and exhibits a gen-eral trend of steady increase during this period. The minimum of 87Sr/86Sr ratios (0.707011) occurs in the Late Permian (30 m in thickness below the Permian-Triassic boundary), and the maximum (0.708281), near the Early-Middle Triassic boundary. The lack of land plants and the rapid continental weathering result in the increase of 87Sr/86Sr ratios during the interval. The Permian-Triassic boundary in Zhongli-ang Mountain Section has been accepted internationally. The 87Sr/86Sr ratios of six samples near the boundary vary from 0.70714 to 0.70715 with an average of 0.70714, which is consistent with the value of 0.70715 (samples are from articulate brachiopod shells) from Korte et al. published in 2006 (within the error range in experiment). Accordingly, the strontium isotope composition in the Permian-Triassic boundary in this paper is of global significance. It can be confirmed that the 87Sr/86Sr ratios of the sea-water in the Permian-Triassic transition are in the range of 0.70714―0.70715.HUANG SiJing Qing HaiRuo HUANG PeiPei HU ZuoWei WANG QingDong ZOU MingLiang LIU HaoNian 2008Science China Earth Sciences2008,51,4:24
2Geochemical characteristics of the Permian Changxing Formation reef dolomites,northeastern Sichuan Basin,China显示文摘The recent discovery of deep and ultra-deep gas reservoirs in the Permian Changxing Formation reefs, northeastern Sichuan Basin is a significant development in marine carbonate oil & gas exploration in China. Reef dolomites and their origins have been major research topics for sedimentologists and oil & gas geologists. The petrography, trace element and isotope geochemistry of the reef dolomites indicated that the dolomites are characterized by low Sr and Mn contents, relatively low Fe contents, very similar δ 13 C and δ 18 O values and very different 87 Sr/ 86 Sr ratios. Although the calculated results of the fluid mixing suggested that a mixture with 85%-95% meteoric water and 5%-15% seawater seemed to be the dolomitizing fluids of the reef dolomites, the low Mn contents, relatively low Fe contents, high δ 13 C values and high homogenization temperatures of the dolomites did not support that there were large proportions of meteoric water in the dolomitization process, and the 87 Sr/ 86 Sr ratios which were close to coeval seawater also did not support the possibility of the mixture of deep-burial circulated fluids from clastic rocks. High temperature deep-burial circulated seawater with low Mn and Fe contents, high Sr content and high δ 13 C values from the dissolution of widely distributed Triassic evaporites during the burial diagenetic processes (including dehydration of water-bearing evaporites) could have been the dolomitizing fluids of the reef dolomites.Hu Zuowei Huang Sijing Li Zhiming Zhang Yingying Xu Ershe Qi Shichao 2013Petroleum Science2013,10,1:6
3Evolution and global correlation for strontium isotopic composition of marine Triassic from Huaying Mountains,eastern Sichuan,China显示文摘Strontium isotope stratigraphy (SIS) has progressively become an efficient chemostratigraphic tool in the research and correlation of global geological events, such as global sea level fluctuations, orogeny, and paleoclimatic and paleoenvironmental changes. In this paper, 87Sr/86Sr ratios of the Triassic marine carbonate rock samples from Huaying Mountains, eastern Sichuan are measured, and the corre-sponding Sr-isotopic curve is constructed, based on the fundamental principle of strontium isotope stratigraphy, analysis of rock fabric, luminescent intensity, chemical composition and representative evaluation for the coeval seawater information. The 87Sr/86Sr ratios show a rapid rise from 0.70721 near the Permian-Triassic transition to 0.70830 at the end of Early Triassic, and then they decline rapidly to 0.70787 in the early Middle Triassic. These data are generally coincident with 87Sr/86Sr ratios of coeval seawater from previous papers, and the curve is also similar to other previous curves. This indicates that the global geological events are the most important controlling factors to the strontium isotope evolution of the global seawater in the Early and Middle Triassic.ZuoWei Hu SiJing Huang HaiRuo Qing QingDong Wang ChunMei Wang XiaoYong Gao 2008Science China Earth Sciences2008,51,4:5
4Copper Catalyzed Asymmetric [4+2] Annulations of D-A Cyclobutanes with Aldehydes显示文摘铜催化 enantioselective [4 + 2 ] D-A 环丁烷和醛的环被开发了。面对一个方面,手臂修改了 chiral bisoxazoline (SaBOX ) ligand,[4 + 2 ] 环顺利继续了一个宽广底层范围。22 个例子被学习,导致与在 41%-99% 收益与的各种各样的功能的组一起的相应产品 > 99/1 医生和 90%-96% ee。与二个酉旨组一起的产生产品是单音还原剂的,给在没有 enantiopurity 的损失的优秀 diastereoselectivity 的相应产品。Jiang-Lin Hu Li Zhou Lijia Wang Zuowei Xie Yong Tang 2018Chinese Journal of Chemistry2018,36,1:5
5Carbon isotope composition and comparison of Lower Triassic marine carbonate rocks from Southern Longmenxia section in Guang'an, Sichuan Basin显示文摘The Early Triassic was a period of ecological restoration for the earth's system after the end-Permian mass extinction.Geochemical records linked to the variations in marine ecosystems during this period have attracted the interest of geologists for many years.Based on petrographic analysis of samples and evaluations of their reliability as proxies for original seawater,this study investigated the carbon and oxygen isotopic compositions of 350 carbonate rock samples from the Lower Triassic(and adjacent strata)in the southern Longmenxia section of Guang'an,eastern Sichuan Basin.The results indicate that the Triassic carbonate rocks from the southern Longmenxia section favorably preserved the original seawater'sδ^(13)C signal.Furthermore,carbon and oxygen isotopic compositions are found to be poorly correlated,with a determination coefficient as low as 0.0205 and only 44 rock samples show results of Mn/Sr>2 and/orδ^(18)0<-6.5‰.The complete carbon isotopic curve for the Lower Triassic is established using the data from the remaining 306 samples with Mn/Sr<2 and/orδ^(18)O>-6.5‰.This curve presents favorable comparability on a global scale,specifically in theδ^(13)C minima near the Permian-Triassic boundary,at the top of the Jia1 and within the the Jia3,as well as in theδ^(13)C maxima at the tops of the Ye1 and Ye4,at the base of the Jia2 and at the top of the Ye3.The peaks and troughs corresponding to these maxima and minima all reflect global signals.By comparing these results to previous research on coeval carbon isotopic curves established within the chronostratigraphic framework,the ages of these critical evolution points are determined.The results show that the Ye1 roughly corresponds to the Griesbachian substage;the Ye2 through Ye4 correspond to the Dienerian substage;Jial corresponds to the Smithian substage;from the Jia2 to the lower part of the Jia4 correspond to the Spathian substage;and the middle and upper parts of the Jia4 belongs to the Aegean Substage of the Middle Triassic.Around the boundary between the Jial and Jia2(which represents the Smithian-Spathian boundary(SSB)),the value ofδ^(13)C increases rapidly from-0.911‰to 3.679‰.The span during which the seawater's carbon isotope experiences this drastic change may be less than36 kyr.The oxygen isotope,which is more sensitive to sedimentary environmental changes,exhibits changes prior to the carbon isotope near the SSB,indicating a significant increase in the salinity of the seawater before a sharp rise in the carbon isotope;this event leads to the formation of evaporites and dolomites.HUANG SiJing HUANG KeKe ZHONG YiJiang LI XiaoNing MAO XiaoDong HU ZuoWei LIU SiBing ZHANG Meng WU WenHui 2017Science China Earth Sciences2017,60,1:4
6Temperatures of dolomitizing fluids in the Feixianguan Formation from the Northeastern Sichuan Basin显示文摘The discovery of natural gas reservoirs from the Triassic Feixianguan Formation in the Northeastern Sichuan Basin is an important breakthrough in the field of marine carbonate rocks for Chinese oil and gas exploration in recent years.Because of the dolomite-hosted reservoirs in the Feixianguan Formation,these dolomites and their formation mechanisms have been a research focus for sedimentary geologists and petroleum geologists.Based on the homogenization temperatures of fluid inclusions,oxygen isotopic composition and their calculated temperatures,and the burial and thermal history of the typical well,it is considered that the majority of dolomites are formed by low-temperature dolomitizing fluids in the Triassic Feixianguan Formation,Northeastern Sichuan Basin.Only a minority of dolomites are formed by high-temperature dolomitizing fluids.The ending depth interval of low-temperature dolomitizing fluids was about 1000-2500 m,of which the correspondingly ending timing interval was approximately from early-middle Middle Triassic to early-middle Late Triassic.The main depth interval of high-temperature dolomitizing fluids was about 3200-4500 m,of which the correspondingly main timing interval was approximately early-middle Middle Jurassic.The low-temperature and high-temperature dolomitizing fluids have different meanings to the formation and evolution of the pore volumes of dolomite reservoirs in the Feixianguan Formation,Northeastern Sichuan Basin.HU ZuoWei HUANG SiJing LI ZhiMing QING HaiRuo FAN Ming LAN YeFang 2012Science China Earth Sciences2012,55,10:4
7Streptococcus suis infection显示文摘Youjun Feng Huimin Zhang Zuowei Wu Shihua Wang Min Cao Dan Hu Changjun Wang 2014Virulence2014,,:1
8AGAP2-AS1 affects TNM staging and prognosis of lung cancer patients by acting on SLC7A11 mRNA stability and ferroptosis显示文摘Objective The initiation and progression of lung carcinomas are critically regulated by long non-coding RNAs(lncRNAs).However,the role of lncRNAs in the pathways causing lung cancer remains unknown.Methods Cell morphology was regularly observed using an inverted phase-contrast microscope.Cell viability was assessed using CCK-8 according to the manufacturer’s instructions.Total RNA was retrotranscribed from each specimen using the RNAiso Plus Kit.The RT-PCR data were calculated using the Ct approach for comparison.Flow cytometric analyses were prepared by Click-iT™Plus TUNEL Assay for In Situ apoptosis detection,with Alexa Fluor^(TM)594 dye,as instructed.RNA immunoprecipitation assays were used to determine RNA concentration.Results Activated natural killer cells repeat and PH domain-containing protein 2 antisense RNA 1(AGAP2-AS1)levels in cancerous tissues were significantly correlated with cancerous tumor node metastasis(TNM)stage,with cancerous AGAP2-AS1 levels being higher in cancerous tissues than healthy tissues.Patients withelevated AGAP2-AS1 levels had considerably worse outcomes than those with reduced AGAP2-AS1 levels,regardless of the progression-free or overall survival.Functionally,AGAP2-AS1 downregulation represseslung cancer cell growth.AGAP2-AS1 elimination induces erastin-mediated ferroptosis in lung cancer cells.However,the ferritin inhibitor FERSINT-1 negated this result,whereas ERASTIN induced lung cancer cellmortality.After AGAP2-AS1 silencing,erastin-treated lung cancer cells showed a remarkable decrease inGSH levels.These results indicated that AGAP2-AS1 enhanced the stabilization of SLC7A11 mRNA via Recombinant Insulin Like Growth Factor Binding Protein 2(IGF BP2).Patients with elevated AGAP2-AS1 had considerably worse outcomes.Down-regulating AGAP2-AS1 was able to repress lung cancer cell growth and induce greater Erastin-mediated ferroptosis.Lungcancer cells treated with Erastin exhibited a remarkable decrease inglutathione(GSH)levels.The mechanical findingsindicated that AGAP2-AS1 enhanced the stabilization of SLC7A11 mRNA via the IGF2BP2.Conclusion We identified a novel effect of AGAP2-AS1 on TNM staging and the prognosis of patientswith lungcancer by modulating SLC7A11 mRNA stability and ferroptosis.Lin Huang Bin Li Zuowei Hu 2023Oncology and Translational Medicine2023,9,3:0
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