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| 1 | Incidence and mortality of stomach cancer in China,2014显示文摘Objective: In this study,we aimed to estimate the updated incidence and mortality rate of stomach cancer based on the cancer registration data in 2014,collected by the National Central Cancer Registry of China(NCCRC).Methods: In 2017,339 registries' data were qualified based on the criteria of data quality control of the NCCRC.Cases of stomach cancer were retrieved from the national database.We estimated numbers of stomach cancer cases and deaths in China using age-specific rates and corresponding national population stratified by area,sex,agegroup(0,1–4,5–9,10–14,…,85+).Chinese standard population in 2000 and Segi's world population were applied for age-standardized incidence and mortality rates.Results: In 2014,410,400 new stomach cancer cases and 293,800 cancer-associated deaths were estimated to have occurred in China.The crude incidence rate of stomach cancer was 30.00/100,000,age-standardized incidence rates by Chinese standard population(ASIRC) and by world standard population(ASIRW) were 19.62/100,000 and19.51/100,000,respectively.The crude mortality rate of stomach cancer was 21.48/100,000,age-standardized mortality rates by Chinese(ASMRC) and by world standard population(ASMRW) were 13.44/100,000 and13.30/100,000,respectively.Incidence and mortality rates in rural areas were both higher than that in urban areas.Stomach cancer has a strong relationship with gender and age.The disease has occurred more frequently among men than women with a male to female ratio of 2.4 for ASIRC.After age group of 40-44 years,incidence rates are substantially higher in men than in women,same pattern was seen for age-specific mortality rates.Conclusions: There is still a heavy burden of stomach cancer in China.The incidence and mortality patterns of stomach cancer show substantial gender and regional disparities.Great effort is needed to provide more accessible health services,sufficient financial resources,and adequate cancer-care infrastructure for the Chinese population,especially for people living in rural areas. | Lei Yang Rongshou Zheng Ning Wang Yannan Yuan Shuo Liu Huichao Li Siwei Zhang Hongmei Zeng Wanqing Chen | 2018 | Chinese Journal of Cancer Research2018，30，3： | 114 |
| 2 | The influence of stage at diagnosis and molecular subtype on breast cancer patient survival: a hospital.based multi.center study显示文摘Background: Stage at diagnosis and molecular subtype are important clinical factors associated with breast cancer patient survival. However, subgroup survival data from a large study sample are limited in China.To estimate the survival differences among patients with different stages and various subtypes of breast cancer, we conducted a hospital-based multi-center study on breast cancer in Beijing, China.Methods: All resident patients diagnosed with primary, invasive breast cancer between January 1,2006 and December 31,2010 from four selected hospitals in Beijing were included and followed up until December 31,2015. Hospitalbased data of stage at diagnosis, hormone receptor status, and selected clinical characteristics, including body mass index(BMI), menopausal status, histological grade, and histological type, were collected from the medical records of the study subjects. Overall survival(OS) and cancer-specific survival(CSS) were estimated. Cox proportional hazards models were employed to evaluate the associations of stage at diagnosis and molecular subtype with patient survival.Results: The 5-year OS and CSS rates for all patients were 89.4% and 90.3%. Survival varied by stage and molecular subtype. The 5-year OS rates for patients with stage I, Ⅱ, Ⅲ, and IV diseases were 96.5%, 91.6%, 74.8%, and 40.7%,respectively, and the corresponding estimates of 5-year CSS rates were 97.1%, 92.6%, 75.6%, and 42.7%, respectively.The 5-year OS rates for patients with luminal A, luminal B, HER2, and triple-negative subtypes of breast cancer were92.6%, 88.4%, 83.6%, and 82.9%, respectively, and the corresponding estimates of 5-year CSS rates were 93.2%, 89.1 %,85.4%, and 83.5%, respectively. Multivariate analysis showed that stage at diagnosis and molecular subtype were important prognostic factors for breast cancer.Conclusions: Survival of breast cancer patients varied significantly by stage and molecular subtype. Cancer screening is encouraged for the early detection and early diagnosis of breast cancer. More advanced therapies and health care policies are needed on HER2 and triple-negative subtypes. | Tingting Zuo Hongmei Zeng Huichao Li Shuo Liu Lei Yang Changfa Xia Rongshou Zheng Fei Ma Lifang Liu Ning Wang Lixue Xuan Wanqing Chen | 2017 | Chinese Journal of Cancer2017，36，11： | 18 |
| 3 | Carbon dioxide capture using polyethylenimine-loaded mesoporous carbons显示文摘A high efficiency sorbent for CO2 capture was developed by loading polyethylenimine (PEI) on mesoporous carbons which possessed well-developed mesoporous structures and large pore volume. The physicochemical properties of the sorbent were characterized by N2 adsorption/desorption, scanning electron microscopy (SEM), thermal gravimetric analysis (TG) and Fourier transform infrared spectroscopy (FT-IR) techniques followed by testing for CO2 capture. Factors that affected the sorption capacity of the sorbent were studied. The sorbent exhibited extraordinary capture capacity with CO2 concentration ranging from 5% to 80%. The optimal PEI loading was determined to be 65 wt.% with a CO2 sorption capacity of 4.82 mmol-CO2 /g-sorbent in 15% CO2 /N2 at 75°C, owing to low mass-transfer resistance and a high utilization ratio of the amine compound (63%). Moisture had a promoting effect on the sorption separation of CO2 . In addition, the developed sorbent could be regenerated easily at 100°C, and it exhibited excellent regenerability and stability. These results indicate that this PEI-loaded mesoporous carbon sorbent should have a good potential for CO2 capture in the future. | Jitong Wang Huichao Chen Huanhuan Zhou Xiaojun Liu Wenming Qiao Donghui Long Licheng Ling | 2013 | Journal of Environmental Sciences2013，25，1： | 9 |
| 4 | Discovery of tip induced unconventional superconductivity on Weyl semimetal显示文摘Weyl fermion is a massless Dirac fermion with definite chirality,which has been long pursued since 1929.Though it has not been observed as a fundamental particle in nature,Weyl fermion can be realized as low-energy excitation around Weyl point in Weyl semimetal,which possesses Weyl fermion cones in the bulk and nontrivial Fermi arc states on the surface. As a firstly discovered Weyl semimetal,Ta As crystal possesses 12 pairs of Weyl points in the momentum space,which are topologically protected against small perturbations. Here,we report for the first time the tip induced superconductivity on Ta As crystal by point contact spectroscopy. The zero bias conductance peak as well as a conductance plateau with double conductance peaks and sharp double dips are observed in the point contact spectra simultaneously,indicating unconventional superconductivity. Our further theoretical study suggests that the induced superconductivity may have nontrivial topology. The present work opens a new route in investigating the novel superconducting states based on Weyl materials. | He Wang Huichao Wang Yuqin Chen Jiawei Luo Zhujun Yuan Jun Liu Yong Wang Shuang Jia Xiong-Jun Liu jian Wei Jian Wang | 2017 | Science Bulletin2017，62，6： | 7 |
| 5 | Collaborative Spectrum Sensing for Illegal Drone Detection: A Deep Learning-Based Image Classification Perspective显示文摘Drones,also known as mini-unmanned aerial vehicles(UAVs),are enjoying great popularity in recent years due to their advantages of low cost,easy to pilot and small size,which also makes them hard to detect.They can provide real time situational awareness information by live videos or high definition pictures and pose serious threats to public security.In this article,we combine collaborative spectrum sensing with deep learning to effectively detect potential illegal drones with states of high uncertainty.First,we formulate the detection of potential illegal drones under illegitimate access and rogue power emission as a quaternary hypothesis test problem.Then,we propose an algorithm of image classification based on convolutional neural network which converts the cooperative spectrum sensing data at a sensing slot into one image.Furthermore,to exploit more information and improve the detection performance,we develop a trajectory classification algorithm which converts theflight process of the drones in consecutive multiple sensing slots into trajectory images.In addition,simulations are provided to verify the proposed methods’performance under various parameter configurations. | Huichao Chen Zheng Wang Linyuan Zhang | 2020 | China Communications2020，17，2： | 6 |
| 6 | miR-27 inhibits adipocyte differentiation via suppressing CREB expression显示文摘miR-27 在 adipogenesis 的规定起一个否定作用。然而,分子的机制尚待是 clarified.In 现在的学习,我们发现 miR-27 由镇压部分禁止 adipogenesis 由直接指向它的 3 untranslated 区域的早 adipogenic transcriptionfactor 营地反应元素绑定蛋白质。另外,我们 demonstratedthat 肿瘤坏死因素 --(TNF-) 通过 NF-B 小径的处理起来调整 miR-27。而且, anti-miR-27 reducesthe TNF -- adipogenesis 的导致的抑制。同时, miR-27 表示的层次在成熟 adipocytesof 被减少肥胖的老鼠什么时候与瘦老鼠相比。我们的数据在 adipogenesis 的规定揭示了 miR-27 的新奇机制。 | Yingjie Zhu Xiaodong Zhang Xingpo Ding Huichao Wang Xiantao Chen Hanzheng Zhao Yudong Jia Sanhong Liu Youwen Liu | 2014 | Acta Biochimica et Biophysica Sinica2014，46，7： | 5 |
| 7 | Carbamazepine degradation by heterogeneous activation of peroxymonosulfate with lanthanum cobaltite perovskite:Performance,mechanism and toxicity显示文摘The widely used carbamazepine(CBZ)is one of the most persistent pharmaceuticals and suffers insufficient removal efficiency by conventional wastewater treatment.A synthesized Co-based perovskite(LaCoO3)was used to activate peroxymonosulfate(PMS)in order to degrade CBZ.Results showed that LaCoO3 exhibited an excellent performance in PMS activation and CBZ degradation at neutral pH,with low cobalt leaching.The results of FT-IR and XPS verified the high structurally and chemically stability of LaCoO3 in PMS activation.Electron spin resonance(ESR)analysis suggested the generation of radical species,such as sulfate radicals(SO4·-)and hydroxyl radicals(·OH).Radical quenching experiments further revealed the responsibility of SO4·-as the dominant oxidant for CBZ oxidation.Ten products were detected via the oxidation of CBZ,with the olefinic double bond attacked by SO4·-as the initial step.Hydroxylation,hydrolysis,cyclization and dehydration were involved along the transformation of CBZ.The toxicity of CBZ solution was significantly reduced after treating by PMS/LaCoO3. | Huichao Guo Xuefei Zhou Yalei Zhang Qiufang Yao Yajie Qian Huaqiang Chu Jiabin Chen | 2020 | Journal of Environmental Sciences2020，32，5： | 4 |
| 8 | A branched dihydrophenazine-based polymer as a cathode material to achieve dual-ion batteries with high energy and power density显示文摘Organic electrode materials have exhibited good electrochemical performance in batteries,but their voltages and rate capabilities still require improvement to meet the increasing demand for batteries with high energy and power density.Herein,we design and synthesize a branched dihydrophenazine-based polymer(p-TPPZ)as a cathode material for dual-ion batteries(DIBs)through delicate molecular design.Compared with the linear dihydrophenazine-based polymer(p-DPPZ,with a theoretical capacity of 209 mAh g^(−1)),p-TPPZ possessed a higher theoretical capacity of 233 mAh g^(−1)and lower highest occupied molecular orbital energy levels,which resulted in a high actual capacity(169.3 mAh g^(−1)at 0.5 C),an average discharge voltage of 3.65 V(vs.Li+/Li)and a high energy density(618.2 Wh kg^(−1),based on the cathode materials).The branched structure of p-TPPZ led to a larger specific surface area than that of p-DPPZ,which was beneficial for the electrolyte infiltration and fast ionic transport,contributing to the high power density.Due to the fast reaction kinetics,even at a power density of 23,725 W kg^(−1)(40 C),the energy density still reached 474.5 Wh kg^(−1).We also made a detailed investigation of the p-TPPZ cathode’s charge storage mechanism.This work will stimulate the further molecular design to develop organic batteries with both high energy and power density. | Shuaifei Xu Huichao Dai Shaolong Zhu Yanchao Wu Mingxuan Sun Yuan Chen Kun Fan Chenyang Zhang Chengliang Wang Wenping Hu | 2021 | eScience2021，1，1： | 2 |
| 9 | Effects of sludge retention time,carbon and initial biomass concentrations on selection process:From activated sludge to polyhydroxyalkanoate accumulating cultures显示文摘Four sequence batch reactors(SBRs) fed by fermented sugar cane wastewater were continuously operated under the aerobic dynamic feeding(ADF) mode with different configurations of sludge retention time(SRT), carbon and initial biomass concentrations to enrich polyhydroxyalkanoate(PHA) accumulating mixed microbial cultures(MMCs) from municipal activated sludge.The stability of SBRs was investigated besides the enrichment performance. The microbial community structures of the enriched MMCs were analyzed using terminal restriction fragment length polymorphism(T-RFLP). The optimum operating conditions for the enrichment process were: SRT of 5 days, carbon concentration of 2.52 g COD/L and initial biomass concentration of3.65 g/L. The best enrichment performance in terms of both operating stability and PHA storage ability of enriched cultures(with the maximum PHA content and PHA storage yield(YPHA/S) of61.26% and 0.68 mg COD/mg COD, respectively) was achieved under this condition. Effects of the SRT, carbon concentration and initial biomass concentration on the PHA accumulating MMCs selection process were discussed respectively. A new model including the segmentation of the enrichment process and the effects of SRT on each phase was proposed. | Zhiqiang Chen Long Huang Qinxue Wen Huichao Zhang Zirui Guo | 2017 | Journal of Environmental Sciences2017，29，2： | 2 |
| 10 | Enhancement of Ca-based sorbent multicyclic behavior in Ca looping process for CO2 separation显示文摘 | Li Yingjie Zhao Changsui Chen Huichao | 2009 | Chemical Engineering & Technology2009，32，4： | 1 |
| 11 | Adaptive 3D Routing Protocol for Flying Ad Hoc Networks Based on Prediction-Driven Q-Learning显示文摘The routing protocols are paramount to guarantee the Quality of Service(QoS)for Flying Ad Hoc Networks(FANETs).However,they still face several challenges owing to high mobility and dynamic topology.This paper mainly focuses on the adaptive routing protocol and proposes a Three Dimensional Q-Learning(3DQ)based routing protocol to guarantee the packet delivery ratio and improve the QoS.In 3DQ routing,we propose a Q-Learning based routing decision scheme,which contains a link-state prediction module and routing decision module.The link-state prediction module allows each Unmanned Aerial Vehicle(UAV)to predict the link-state of Neighboring UAVs(NUs),considering their Three Dimensional mobility and packet arrival.Then,UAV can produce routing decisions with the help of the routing decision module considering the link-state.We evaluate the various performance of 3DQ routing,and simulation results demonstrate that 3DQ can improve packet delivery ratio,goodput and delay of baseline protocol at most 71.36%,89.32%and 83.54%in FANETs over a variety of communication scenarios. | Min Zhang Chao Dong Simeng Feng Xin Guan Huichao Chen Qihui Wu | 2022 | China Communications2022，19，5： | 1 |
| 12 | High-fidelity,low-latency polarization quantum state transmissions over a hollow-core conjoined-tube fiber at around 800 nm显示文摘Hollow-core fiber(HCF)promises to unify air-borne light propagation and non-line-of-sight transmission,thus holding great potential for versatile photonics-based quantum information applications.The early version of HCF based on photonic-bandgap guidance has not proven itself a reliable quantum channel because of the poor modal purity in both spatial and polarization domains,as well as significant difficulty in fabrication when the wavelength shifts to the visible region.In this work,based on the polarization degree of freedom,we demonstrate high-fidelity(∼0.98)single-photon transmission and distribution of entangled photons over a 36.4 m hollow-core conjoined-tube fiber(CTF)by using commercial silicon single-photon avalanche photodiodes.Our CTF realizes the combined merits of low loss,high spatial modal purity,low polarization degradation,and low chromatic dispersion.We also demonstrate single-photon low-latency(∼99.96%speed of light in vacuum)transmission,paving the way for extensive uses of HCF links in versatile photonics-based quantum information processing. | Xinyu Chen Wei Ding Ying-Ying Wang Shou-Fei Gao Feixiang Xu Huichao Xu Yi-Feng Hong Yi-Zhi Sun Pu Wang Yan-Qing Lu Lijian Zhang | 2021 | Photonics Research2021，9，4： | 1 |
| 13 | Cyclic CO2 capture behavior of KMnO4-doped CaO based sorbent 显示文摘 | LI Yingjie ZHAO Changsui CHEN Huichao | 2010 | Fuel2010，89，3： | 1 |
| 14 | En-hancement of Ca-based sorbent multicyclic behavior in Ca looping process for CO 2 separation显示文摘 | LI Yingjie ZHAO Changsui CHEN Huichao | 2009 | Chemical Engi-neering&Technology2009，32，4： | 1 |
| 15 | Laser-annealing-made amplified spontaneous emission of 'giant' CdSe/CdS core/shell nanocrystals transferred from bulk-like shell to quantum-confined core显示文摘'Giant' Cd Se/Cd S core/shell nanocrystals(NCs) were synthesized with thick Cd S shell(15 monolayers), and the x-ray diffraction(XRD) measurement indicates there is a zinc blende phase in the thick Cd S shell, whereas it transformed into wurtzite phase under 5 min radiation with a 400 nm, 594 μJ∕cm2femtosecond(fs) laser beam.The evolution of the NCs’ spontaneous emission under the fs laser radiation was recorded with a Hamamatsu streak camera. The as-synthesized NCs exhibit an amplified spontaneous emission(ASE) at 530 nm, which comes from a bulk-like Cd S shell due to the interfacial potential barrier, which could slow down the relaxation of holes from the shell to the core. After being annealed by an fs laser, the ASE of the g-NCs is transferred from a bulk-like Cd S shell to a quantum-confined Cd Se core because the phase transformation determined with the XRD measurement could remove the interfacial barrier. Besides the ASE at 643 nm, two shorter-wavelength ASE peaks at 589 and 541 nm, corresponding to optical transitions of the second(1P) and third(1D) electron quantization shells of the Cd Se core, also appear, thus indicating that Auger recombination is effectively suppressed. | Chen Liao Kai Fan Ruilin Xu Huichao Zhang Changgui Lu Yiping Cui Jiayu Zhang | 2015 | Photonics Research2015，3，5： | 1 |
| 16 | Biodegradation of polyacrylamide by bacteria isolated from activated sludge and oil-contaminated soil显示文摘 | Qinxue Wen Zhiqiang Chen Ye Zhao Huichao Zhang Yujie Feng | 2009 | Journal of Hazardous Materials2009，，1： | 1 |
| 17 | OTFS Modulation and PAPR Reduction for IoT-Railways显示文摘The internet of things(IoT)has been widely considered to be integrated with high-speed railways to improve safety and service.It is important to achieve reliable communication in IoT for railways(IoT-R)under high mobility scenarios and strict energy constraints.Orthogonal time frequency space(OTFS)modulation is a two-dimensional modulation technique that has the potential to overcome the challenges in high Doppler environments.In addition,OTFS can have lower peak-to-average power ratio(PAPR)compared to orthogonal frequency division multiplexing,which is especially important for the application of IoT-R.Therefore,OTFS modulation for IoT-R is investigated in this paper.In order to decrease PAPR of OTFS and promote the application of OTFS modulation in IoT-R,the peak windowing technique is used in this paper.This technique can reduce the PAPR of OTFS by reducing the peak power and does not require multiple iterations.The impacts of different window functions,window sizes and clipping levels on PAPR and bit error rate of OTFS are simulated and discussed.The simulation results show that the peak windowing technique can efficiently reduce the PAPR of OTFS for IoT-R. | Huichao Shang Ruifeng Chen Haoxiang Zhang Guoyu Ma Ruisi He Bo Ai Zhangdui Zhong | 2023 | China Communications2023，20，1： | 1 |
| 18 | Green and Effective Ammonium Carbonate-assisted Process for Drying Hemicellulose Obtained through Alkali Extraction of Bleached Bamboo Kraft Pulp显示文摘Hemicellulose has a wide range of applications,including that as an emulsifier for the food industry and raw material for the synthesis of bioethanol/biochemicals and biodegradable films.Hemicellulose is usually present as a spent liquor,such as the prehydrolysis liquor of the prehydrolysis kraft dissolving pulp production process and the alkali extraction liquor of the cold caustic extraction of pulp fibers.Due to its dilute nature,hemicellulose needs to be dried for practical utilization,and this is challenging.In this study,cellulose and hemicellulose in a bleached bamboo kraft pulp were separated using an alkali extraction process.Hemicellulose obtained from the extraction liquor was dried by an ammonium carbonate-assisted drying process.The effects of drying time and drying temperature were determined.Structure of the hemicellulose obtained by the ammonium carbonate-assisted drying process was similar to that of original hemicellulose,as revealed by detailed Fourier transform infrared and X-ray diffraction analyses.The novel drying method was more energy efficient and required a shorter drying time than the conventional freeze drying method,and the excellent solubility in alkaline solutions favored the chemical modification of hemicellulose.The dried hemicellulose can be used as a renewable raw material for the preparation of hydrogels and other substances such as bioethanol/biochemicals and biodegradable films. | Xiaoqi Gong Zongwei Zhang Yonghao Ni Xinhua Ouyang Lihui Chen Liulian Huang Huichao Hu | 2021 | Paper And Biomaterials2021，6，1： | 1 |
| 19 | Modified CaO-based sorbent looping cycle for CO2 mitigation 显示文摘 | Li Yingjie Zhao Changsui Chen Huichao | 2009 | Fuel2009，88，4： | 1 |
| 20 | Novel recombinant R-spondin1 promotes hair regeneration by targeting the Wnt/β-catenin signaling pathway显示文摘Roof plate-specific spondin 1(R-spondin1,RSPO1)is a Wnt/β-catenin signaling pathway activator that binds with Wnt ligands to stimulate the Wnt/β-catenin signaling pathway,which is key to hair regeneration.However,it is not clear whether recombinant RSPO1(rRSPO1)affects hair regeneration.Here,we treat C57BL/6 male mice with rRSPO1 and investigate the expression of the Wnt/β-catenin signaling pathway and the activation of hair follicle stem cells in the dorsal skin.The mouse skin color score and hair-covered area are determined to describe hair growth,and the skin samples are subjected to H&E staining,western blot analysis and immunofluorescence staining to evaluate hair follicle development and the expressions of Wnt/β-catenin signaling pathway-related proteins.We find that rRSPO1 activates mouse hair follicle stem cells(mHFSCs)and accelerates hair regeneration.rRSPO1 increases the hair-covered area,the number of hair follicles,and the hair follicle diameter and length.Moreover,rRSPO1 enhances the activity of Wnt/β-catenin signaling pathway-related proteins and the expressions of HFSC markers,as well as mHFSC viability.These results indicate that subcutaneous injection of rRSPO1 can improve hair follicle development by activating the Wnt/β-catenin signaling pathway,thereby promoting hair regeneration.This study demonstrates that rRSPO1 has the potential to treat hair loss by activating the Wnt/β-catenin signaling pathway. | Yijun Chen Zhujin Lu Jiaxin Feng Zefeng Chen Zejian Liu Xiuqi Wang Huichao Yan Chunqi Gao | 2023 | Acta Biochimica et Biophysica Sinica2023，55，8： | 0 |
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