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| 1 | Cryo-self-assembled silk fibroin sponge as a biodegradable platform for enzyme-responsive delivery of exosomes显示文摘Although advances in protein assembly preparation have provided a new platform for drug delivery during tissue engineering,achieving long-term controlled exosome delivery remains a significant challenge.Diffusion-dominated exosome release using protein hydrogels results in burst release of exosomes.Here,a fibroin-based cryo-sponge was developed to provide controlled exosome release.Fibroin chains can self-assemble into silk I structures under ice-cold conditions when annealed above the glass transition temperature.Exosome release is enzyme-responsive,with rates primarily determined by enzymatic degradation of the scaffolds.In vivo experiments have demonstrated that exosomes remain in undigested sponge material for two months,superior to their retention in fibrin glue,a commonly used biomaterial in clinical practice.Fibroin cryo-sponges were implanted subcutaneously in nude mice.The exosome-containing sponge group exhibited better neovascularization and tissue ingrowth effects,demonstrating the efficacy of this exosome-encapsulating strategy by realizing sustained release and maintaining exosome bioactivity.These silk fibroin cryo-sponges containing exosomes provide a new platform for future studies of exosome therapy. | Muyang Sun Qi Li Huilei Yu Jin Cheng Nier Wu Weili Shi Fengyuan Zhao Zhenxing Shao Qingyang Meng Haifeng Chen Xiaoqing Hu Yingfang Ao | 2022 | Bioactive Materials2022，7，2： | 4 |
| 2 | A review on the effects of TiO_(2) surface point defects on CO_(2) photoreduction with H_(2)O显示文摘Photocatalytic reduction of CO_(2) with water by photocatalysts such as TiO_(2) to produce solar fuels is an attractive approach to alleviate the environmental influences of greenhouse gases and in the meantime produce valuable carbon-neutral fuels.Among the materials properties that affect catalytic activity of CO_(2) photoreduction,the point defect on TiO_(2) is one of the most important but not frequently addressed and well understood in the literature.In this review,we have examined the major influences of TiO_(2) point defects on CO_(2)photoreduction with H_(2)O,by changing the catalysts'gas adsorption capabilities,optical properties,and electronic structures.In addition,the performances of various defective TiO_(2) toward CO_(2) photoreduction are summarized and compared in terms of productivity,selectivity,and stability.We hope this review can contribute to understanding the mechanism of CO_(2) photoreduction on defective TiO_(2) and provide insights to the design of highly efficient defect-rich TiO_(2) to boost the CO_(2) utilization. | Huilei Zhao Fuping Pan Ying Li | 2017 | Journal of Materiomics2017，3，1： | 3 |
| 3 | Microbial diversity in two cold springs on the Qinghai-Tibetan Plateau显示文摘在 Wuli 区域的微生物引起的差异, Qinghai 西藏的高原用 16S rRNA 基因被调查种系发生的分析。一个总数 117 细菌并且 66 archaeal 16S rRNA 基因克隆从 Wuli 寒冷被获得弹簧。细菌的克隆能被分类进 Proteobacteria, Acidobacteria, Deinococci, Sphingobacteria, Flavobacteria, Nitrospirae, Actinobacteria, Gemmatimonadetes,并且未分类细菌;并且 archaeal 克隆能被分类进 Crenarchaeota 和 Thaumarchaeota。在主要的组之中, Proteobacteria 和 Crenarchaeota 是主导的在细菌并且 archaeal 16S rRNA 基因克隆图书馆分别地。在 Wuli 冷弹簧获得的克隆序列是仔细与那些有关从冷产地,例如高山上或在高纬度的雪 / 冰 / 土壤。特别, Wuli 区域的微生物引起的社区作文比另外的地点的冷环境在西藏的冰河更类似于那。在这研究介绍的数据在 Qinghai 西藏的高原上在冷弹簧为微生物引起的差异的更好的理解有含意。 | Gaoyuan Li Hongchen Jiang Weiguo Hou Shang Wang Liuqin Huang Huilei Ren Shicai Deng Hailiang Dong | 2012 | Geoscience Frontiers2012，3，3： | 3 |
| 4 | Feedforward control for nitrogen removal in a pilot-scale anaerobic-anoxic-oxic plant for municipal wastewater treatment显示文摘To improve the efficiency of nitrogen removalwith lower energy consumption,the study of feedforwardcontrol was carried out on a pilot-scale anaerobic-anoxicoxic(AAO)plant for the treatment of municipal wastewater.The effluent qualities of the pilot plant underdifferent control strategies were investigated.The resultsindicated that the change of external recycle was not asuitable approach to regulate the sludge concentration ofplug-flow reactors;adjusting the aeration valve anddissolved oxygen set-point according to ammonia loadcould overcome the impact of influent fluctuation;and thedenitrification potential could be estimated based on thetransit time of anoxic zone and the relative content ofcarbon resource entering the anoxic zone.Simple feedforwardcontrol strategies for aeration and internal recyclewere subsequently proposed and validated.The nitrogenremoval was successfully improved in the pilot plant.Theeffluent total nitrogen had decreased by 29.9%and wassteadily controlled below 15 mg·L^(-1).Furthermore,approximately 38%of the energy for aeration had beensaved. | Tonggang SHEN Hanchang SHI Huiming SHI He JING Huilei XIONG | 2011 | Frontiers of Environmental Science & Engineering2011，5，1： | 3 |
| 5 | A shear-thinning,ROS-scavenging hydrogel combined with dental pulp stem cells promotes spinal cord repair by inhibiting ferroptosis显示文摘Spinal cord injury(SCI)is a serious clinical disease.Due to the deformability and fragility of the spinal cord,overly rigid hydrogels cannot be used to treat SCI.Hence,we used TPA and Laponite to develop a hydrogel with shear-thinning ability.This hydrogel exhibits good deformation,allowing it to match the physical properties of the spinal cord;additionally,this hydrogel scavenges ROS well,allowing it to inhibit the lipid peroxidation caused by ferroptosis.According to the in vivo studies,the TPA@Laponite hydrogel could synergistically inhibit ferroptosis by improving vascular function and regulating iron metabolism.In addition,dental pulp stem cells(DPSCs)were introduced into the TPA@Laponite hydrogel to regulate the ratios of excitatory and inhibitory synapses.It was shown that this combination biomaterial effectively reduced muscle spasms and promoted recovery from SCI. | Yibo Ying Zhiyang Huang Yurong Tu Qiuji Wu Zhaoyu Li Yifan Zhang Huilei Yu Annian Zeng Hanzhi Huang Jiahui Ye Weiyang Ying Min Chen Zhiyi Feng Ziyue Xiang Qingsong Ye Sipin Zhu Zhouguang Wang | 2023 | Bioactive Materials2023，，4： | 2 |
| 6 | Astrocyte elevated gene-1: a novel independent prognostic biomarker for metastatic ovarian tumors显示文摘 | Cong Li Kexin Chen Jianping Cai Qing-Tao Shi Yinghong Li Lejing Li Hongtao Song Huilei Qiu Yu Qin Jing-Shu Geng | 2014 | Tumor Biology2014，，4： | 1 |
| 7 | Influences of volatile solid concentration, temperature and solid retention time for the hydrolysis of waste activated sludge to recover volatile fatty acids显示文摘 | Huilei Xiong Jinluan Chen Hui Wang Hanchang Shi | 2012 | Bioresource Technology2012，，： | 1 |
| 8 | Air-water interfacial titania film self-assembled by CTAB in the presence of gelatin显示文摘 | Liu Xiaoheng Wang Xin | 2006 | Mat Sci Eng A2006，，435436： | 1 |
| 9 | Low VOC, low viscosity UV cationic radiation-cured ink-jet ink system显示文摘 | Huilei Zhang John L. Massingill James T. K. Woo | 2000 | Journal of Coatings Technology2000，，6： | 1 |
| 10 | Influences of volatile solid concentration,temperature and solid retention time for the hydrolysis of waste activated sludge to recover volatile fatty acids显示文摘 | XIONG Huilei CHEN Jinluan WANG Hui | 2012 | Bioresource Technology2012，119，1： | 1 |
| 11 | Enzymatic Production of L-menthol by a high substrate concentration tolerable esterase from newly isolated Bacillus subtilis ECU0554显示文摘 | Zheng Gaowei Yu Huilei Zhang Jiandong | 2009 | Adv Synth Catal2009，351，： | 1 |
| 12 | Low VOC low viscosity UV cationic radiation - cured ink - jet ink system 显示文摘 | HUILEI ZHANG JOHN L MASSINGILL | 2000 | Journal of Coatings Technology2000，72，6： | 1 |
| 13 | Synthesis of novel salidroside esters by lipase-mediated acylation with various functional acyl groups显示文摘 | Huilei Y Jianhe X Jinhuan S | 2008 | Journal of Bi- oscience and Bioengineering2008，106，1： | 1 |
| 14 | ImpI'oved o- chlorobenzoylformate bioreduction by stabilizing aldo-keto reductase YtbE with additives显示文摘 | XU Yanpeng GUAN Yuehugh YU Huilei | 2014 | Journal of molecular catalysis B: enzymatic2014，104，2： | 1 |
| 15 | Immobilization of trophic anaerobic acetogen for semi-continuous syngas fermentation显示文摘The massive consumption of fossil energy force s people to find new source s of energy.Syngas fermentation has become a hot research field as its high potential in renewable energy production and sustainable development.In this study,trophic anaerobic acetogen Morella thermoacetica was successfully immobilized by calcium alginate embedding method.The ability of the immobilized cells on production of acetic acid through syngas fermentation was compared in both airlift and bubble column bioreactors.The bubble column bioreactor was selected as the better type of bioreactor.The production of acetic acid reached 32.3 g·L^(-1) in bubble column bioreactor with a space-time yield of 2.13 g·L^(-1)·d^(-1).The immobilized acetogen could be efficiently reused without significant lag period,even if exposed to air for a short time.A semi-continuous syngas fermentation was performed using immobilized cells,with an average space-time acetic acid yield of 3.20 g·L^(-1)·d^(-1).After 30 days of fermentation,no significant decrea se of the acetic acid production rate was observed. | Lijuan Zhang Peng Hu Jiang Pan Huilei Yu Jianhe Xu | 2021 | Chinese Journal of Chemical Engineering2021，34，1： | 1 |
| 16 | Enzymatic production of 1-menthol by a high substrate concentration tolerable esterase from newly isolated Bacillus subtilis ECU0554 显示文摘 | Zheng Gaowei Yu Huilei Zhang Jiandong | 2009 | Adv Syn Catal2009，351，： | 1 |
| 17 | 全景E3畅想新十年 E3 2010专题式全面解读——今年是充满改变的一年显示文摘由于在微软展前发布会的前一天晚上参加了举办到深夜的Kinect发布体验活动,回来后还要整理资料以及准备今天的发布会,导致只睡了四小时左右。早上7点钟,被闹钟吵醒的我起床稍微洗澈了一下,然后背着背包抓起一罐红牛就出发了。 | Huilei | 2010 | 游戏机实用技术2010，，14： | 0 |
| 18 | 创造游戏新次元 任天堂E2 2010发布会随笔显示文摘今年的任天堂发布会选在洛杉矶市中心的诺基亚剧院(Nokla Theater)举行,而其旁边就是去年任天堂发布会的举办场所诺基亚广场(Nokla Plaza)。虽然那附近的停车状况比昨天的威尔顿剧院要好一些,但由于发布会预定于上午9点开始,比昨天还早一个小时,我不得不在早上6点刚过就起床。 | Huilei | 2010 | 游戏机实用技术2010，，14： | 0 |
| 19 | 惊喜不足,精彩依旧——索尼E3 2010发布会实录显示文摘今年索尼E3发布会的时间原本是定在上午11:30,但也许是觉得和任天堂发布会相隔时间过短吧,为了保险起见最后还是改到了正午12:00。不过由于这次任天堂发布会非常紧凑,在10:20左右就结束了,所以索尼的慎重反倒给了任天堂一些额外的时间来进行发布会后的试玩活动。 | Huilei | 2010 | 游戏机实用技术2010，，14： | 0 |
| 20 | 下站:家庭娱乐 微软Kinect发布体验活动随笔显示文摘由于微软在去年E3发布会上公布的体感控制器“初生计划”(Project Natal)产生了巨大的轰动效应,各界人士都十分关注这款采用了“火星技术”的体感外设在本届E3的实际表现。 | Huilei | 2010 | 游戏机实用技术2010，，14： | 0 |
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