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34篇 您的检索式:作者名="Hulit"
    题名 作者 年代 出处 被引量
1ErbPr2-induced mammary tumor growth:the role cyclinD1 and p27^Kip1 显示文摘Hulit J Lee R J Pestell RG 2002Biochem Pharm2002,64,56:1
2N-cadherin signaling potentiates mammary tumor metastasis via enhanced extracellular signal-regulated kinase activation显示文摘Hulit J Suyama K Chung S 2007Cancer Res2007,67,7:1
3Recent advances in inducible expression in transgenic mice显示文摘Albanese C Hulit J Sakamaki T 2002Semin Cell Dev Biol2002,13,:1
4The integrin-linked kinase regulates the cyclin D1 gene through glycogen synthase kinase 3beta and cAMP-responsive element-binding protein-dependent pathways 显示文摘D'Amico M Hulit J Amanatullah DF 2000J Biol Chem2000,275,32:1
5Recent adances in inducible expression in transgenic mice显示文摘Albanese C Hulit J Sakamaki T 2002Cell Develop Biol2002,13,:1
6Cyclin D1 genetic heterozygosity regulates colonic epithelial cell differentiation and tumor number in ApcMin mice 显示文摘Hulit J Wang C Li Z 2004Mol Cell Biol2004,24,17:1
7Differential Cadherin Expression: Potential Markers for Epithelial to Mesenchymal Transformation During Tumor Progression显示文摘Georgia Agiostratidou James Hulit Greg R. Phillips Rachel B. Hazan 2007Journal of Mammary Gland Biology and Neoplasia2007,,2:1
8ErbB-2-induced mammary tumor growth : the role of cyclin D1 and p27kipl 显示文摘Hulit J Lee RJ Russell RG 2002Biochem Pharmacol2002,64,56:1
9The Cyclin D1 Gene Is lYanscriptionally Repressed by Caveolin-1 显示文摘Hulit J Bash T Fu M 2000J Biol Chemi2000,275,21:1
10N-cadherin signaling potentiates mammary tumor metastasis via enhanced extracellular signal-regulated kinase activation 显示文摘Hulit J Suyama K Chung S 2007Cancer Res2007,67,7:1
11The cyclin D1 gene is transcription- ally repressed by caveolin-1 显示文摘Hulit J Bash T Fu M 2000J Biol Chem2000,275,21:1
12Monomeric red fluorescent proteins with a large stokes shift显示文摘Piatkevich KD Hulit J Subach OM 2010Proc Natl Acad Sci USA2010,107,:1
13The cyclinD1 gene is transcriptionally repressed by caveolin-1显示文摘Hulit J Bash T Fu M 2000J Biol Chem2000,275,21:1
14N cadherin signaling po- tentiates mammary tumor metastasis via enhanced extracellular signal regulated kinase activation显示文摘Hulit J Suyama K Chung S 2007Cancer Res2007,67,7:1
15The cyclin D1 gene is transcriptionally repressed by caveolin-1 显示文摘Hulit J Bash T Pestell RG 2000Biol Chem2000,275,21:1
16The integrin-linked kinase regulates the cyclin D1 gene through glycogen synthase kinase 3beta and cAMP-respon- sive element-binding protein-dependent pathways 显示文摘D'Amico M Hulit J Amanatullah DF Zafonte BT Albanese C Bouzahzah B 2000Biol Chem2000,275,32:1
17The cyclin D1 gene is transcriptionally repressed by caveolin-1 显示文摘Hulit J Bash T Fu M 2000J Biol Chem2000,275,21:1
18Roles of cell fusion, hybridization and polyploid cell formation in cancer metastasis显示文摘Cell-cell fusion is a normal biological process playing essential roles in organ formation and tissue differentiation,repair and regeneration.Through cell fusion somatic cells undergo rapid nuclear reprogramming and epigenetic modifications to form hybrid cells with new genetic and phenotypic properties at a rate exceeding that achievable by random mutations.Factors that stimulate cell fusion are inflammation and hypoxia.Fusion of cancer cells with non-neoplastic cells facilitates several malignancy-related cell phenotypes,e.g.,reprogramming of somatic cell into induced pluripotent stem cells and epithelial to mesenchymal transition.There is now considerable in vitro,in vivo and clinical evidence that fusion of cancer cells with motile leucocytes such as macrophages plays a major role in cancer metastasis.Of the many changes in cancer cells after hybridizing with leucocytes,it is notable that hybrids acquire resistance to chemo-and radiation therapy.One phenomenon that has been largely overlooked yet plays a role in these processes is polyploidization.Regardless of the mechanism of polyploid cell formation,it happens in response to genotoxic stresses and enhances a cancer cell’s ability to survive.Here we summarize the recent progress in research of cell fusion and with a focus on an important role for polyploid cells in cancer metastasis.In addition,we discuss the clinical evidence and the importance of cell fusion and polyploidization in solid tumors.Ivan Shabo Joar Svanvik Annelie Lindström Tanguy Lechertier Sara Trabulo James Hulit Tim Sparey John Pawelek 2020World Journal of Clinical Oncology2020,11,3:1
19Differential eadher- in expression: potential markers for epithelial to mesenchymal transformation during tumor progression 显示文摘Agiostratidou G Hulit J Phillips GR 2007J Mammary Gland Biol Neoplasia2007,12,:1
20ErbB-2-induced mammary tumor growth:the role ofcyclin D1 and p27kip1显示文摘HULIT J LEE RJ RUSSELL RG 2002Biochem Pharma col2002,64,:1
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