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| 1 | Computer Aided Simulation on Precision Cold Forging of Universal Joint Cross显示文摘The 3D FEM numerical simulation on multi-action precision cold forging technology of universal joint cross and differential spider is done in this article using DEFORM Software, a commercial computer aided engineering software specializing in forming and heat treatment simulation technology, and suitable for cold, warm and hot forging process. The material flow properties, the dynamic variation of stress and strain in the process of deformation and the load-stroke curve have also been achieved. A good consistency is exhibited between simulation results and practical data. Based on the DEFORM simulation results, the optimized procedure has been found for forging a universal joint cross. What should be emphasized here is that a better understanding of practical forging characters and the environmental factors can greatly improve the simulation accuracy thus make the simulation results more reliable. | H. Liu, G.N Liu, K J Huo ,T Liu, X H Zhang, K Liu, K Tao, Y. J. Liu 1. Mechanical Engineering School, Xi’an Jiaotong University, Xi’an, 710049, China 2.Strength Centre, Zhengzhou Research Institute of Mechanical Engineering, Zhengzhou 450052, China 3.Fo | 2000 | Journal of Shanghai Jiaotong university(Science)2000，5，1： | 7 |
| 2 | Common non-synonymous polymorphisms in the BRCA1 Associated RING Domain (BARD1) gene are associated with breast cancer susceptibility:a case-control analysis显示文摘The BRCA1 Associated RING Domain(BARD1) gene has been identified as a high penetrance gene for breast cancer, whose germline and somatic mutations were reported in both non-BRCA1/2 hereditary site-specific and sporadic breast cancer cases. BARD1 plays a crucial role in tumor repression, along with its heterodimeric partner BRCA1. In the current study, we tested the hypothesis that common non-synonymous polymorphisms in BARD1 are associated with breast cancer susceptibility in a case-control study of 507 patients with incident breast cancer and 539 frequency-matched cancer-free controls in Chinese women. We genotyped all three common(minor allele frequency (MAF) > 0.10) non-synonymous polymorphisms(Pro24Ser, Arg378Ser, and Val507Met) in BARD1. We found that the BARD1 Pro24Ser variant genotypes(24Pro/Ser and 24Ser/Ser) and Arg378Ser variant homozygote 378Ser/Ser were associated with a significantly decreased breast cancer risk, compared with their wild-type homozygotes, respectively. Furthermore, a significant locus-locus interaction was evident between Pro24Ser and Arg378Ser (P-int = 0.032). Among the 378Ser variant allele carriers, the 24Pro/Pro wild-type homozygote was associated with a significantly increased breast cancer risk (adjusted OR = 1.81, 95% CI = 1.11-2.95), but the subjects having 24Pro/Ser or Ser/Ser variant genotypes had a significantly decreased risk(adjusted OR = 0.74, 95% CI = 0.56-0.99). In stratified analysis, this locus-locus interaction was more evident among subjects without family cancer history, those with positive estrogen receptor (ER) and individuals with negative progesterone receptor(PR). These findings indicate that the potentially functional polymorphisms Pro24Ser and Arg378Ser in BARD1 may jointly contribute to the susceptibility of breast cancer. | Huo, X Hu, Z. B Zhai, X. J Wang, Y Wang, S Wang, X. C Qin, J. W Chen, W. S Jin, G. F Liu, J. Y Gao, J Wei, Q. Y Wang, X. R Shen, H. B | 2007 | 南京医科大学学报(自然科学版)2007，27，7： | 3 |
| 3 | 肺动脉高压患者的负荷适应性显示文摘已知右心室对压力超负荷的适应是肺动脉高压(pulmonary arterial hypertension,PAH)患者预后的主要影响因素。为了评估右心室适应和负荷之间的关系,然后比较PAH中不同负荷适应性指数的预后价值,Amsallem及其同事纳入推导队列(n=85)和验证队列(n=200),使用3种方法评估负荷适应性:①脑室动脉耦合的替代物(例如右心室面积变化/收缩末期面积); | 刘莉 叶鹏 Amsallem M Boulate D Aymami M Guihaire J Selej M Huo J Denault AY McConnell MV Schnittger I Fadel E Mercier O Zamanian RT Haddad F | 2017 | 中华高血压杂志2017，25，8： | 2 |
| 4 | 高血压患者血清磷酸盐与新发高尿酸血症风险的关系显示文摘血清磷酸盐与新发高尿酸血症的关系仍不确定。该研究对中国脑卒中一级预防试验(China stroke primary prevention trial,CSPPT)的尿酸亚组研究进行事后分析,旨在评估血清磷酸盐与新发高血尿酸症的风险之间的关系。研究包括基线尿酸水平正常(<357μmol/L)的参与者共10612人。主要观察指标是新发高血尿酸症,其定义为男性血尿酸浓度≥417或女性≥357μmol/L。在中位数为4.4年的随访期间,1663名(15.7%)参与者发生了新发高尿酸血症。 | 刘莉(译) 叶鹏(摘、审校) Cao J Zhang J Li Q Jiang C Song Y Liu C Liu L Wang B Li J Zhang Y Cui Y Huo Y Wang X Tang G Xu X Qin X | 2019 | 中华高血压杂志2019，27，6： | 2 |
| 5 | Triblock copolymer syntheses of mesoporous silica with periodic 50 to 300 angstrom pores 显示文摘 | Zhao D Y Feng J L Huo Q S | 1998 | Science1998，279，： | 1 |
| 6 | Srglcal access to tumors of the cervieothracic Junction 显示文摘 | Kraus Dh Huo J Burr M | 1995 | Head Neck1995，17，： | 1 |
| 7 | What′s new in total hip arthroplasty显示文摘 | Huo MH Parvizi J Bal BS | 2009 | J Bone Joint Surg2009，91，10： | 1 |
| 8 | Nonionic triblock and star diblock copolymer and oligomeric surfactant syntheses of highly ordered, hydrothermally stable, mesoporous silica structures显示文摘 | Zhao D Huo Q Feng J | 1998 | Journal of the American Chemical Society1998，120，： | 1 |
| 9 | Triblock copolymer syntheses of mesoporous silica with periodic 50 to 300 angstrom pores显示文摘 | ZHAO D FENG J HUO Q MELOSH N FREDRICKSON G H CHMELKA B F STUCKY G D | 1998 | Science1998，279，5350： | 1 |
| 10 | Triblock Copolymer Syntheses of Mesoporous Silica with Periodic 50 to 300 Angstrom Pores显示文摘 | Zhao D Y Feng J L Huo Q S | 1998 | Science1998，279，： | 1 |
| 11 | Triblock copolymer syntheses of mesoporous silica with periodic 50 to 300 angstrom pores 显示文摘 | Zhao D Feng Y J Huo Q | 1998 | Science1998，279，5350： | 1 |
| 12 | A Physical Model for On-Chip Spiral Inductors With Accurate Substrate Modeling显示文摘 | Huo X Philip C H Kevin J C | 2006 | IEEE Trans Electron Devices2006，53，12： | 1 |
| 13 | Triblock copolymer syntheses of mesoporous silica with periodic 50 to 300 angstorm pores 显示文摘 | Zhao D Y Feng J L Huo Q S | 1998 | Science1998，279，5350： | 1 |
| 14 | 2013, Antigenic and genetic characterization of a European avian-like H1N1 swine influenza virus from a boy in China in 2011显示文摘 | Qi x Cui L Jiao Y Pan Y Li X Zu R Huo X Wu B Tang F Song Y Zhou M Wang H Cardona C J Xing Z | 2013 | Archives of Virology2013，158，1： | 1 |
| 15 | A comparative study of electrochemical properties of two kinds of carbon nanotubes as anode materials for lithium ion batteries显示文摘 | Yang S Huo J Song H | 2008 | Electrochim Acta2008，53，5： | 1 |
| 16 | A meta-analysis of randomized controlled trials comparing tacrolimus with intravenous cyclophosphamide in the induction treatment for lupus nephritis显示文摘 | Deng J Huo D Wu Q | 2012 | Tohoku J Exp Med2012，227，4： | 1 |
| 17 | Triblock copolymer syntheses of mesoporous silica with periodic 50 to 300 angstrom pores显示文摘 | Zhao D Y Feng J L Huo Q S | 1998 | Science1998，279，23： | 1 |
| 18 | Efficacy of folic acid therapy in primary prevention of stroke among adults with hypertension in China: the CSPPT randomized clinical trial 显示文摘 | Huo Y Li J Qin X | 2015 | JAMA2015，313，13： | 1 |
| 19 | Comparison of sensitiza- tion between fl-lactoglobulin and its hydrolysates显示文摘 | DUAN C C HUO G C YANG L J | 2012 | AsianPac J Aller- gy Immunol2012，30，1： | 1 |
| 20 | Facile Synthesis Under Near-at- mospheric Conditions and Physicochemical Properties of Hairy CeO2 Nanocrystallines 显示文摘 | LI X D LI J G HUO D | 2009 | Journal of Physical Chemistry C2009，113，5： | 1 |
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