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| 1 | 莲子壳提取物中黄酮类物质的抗氧化活性及结构初探显示文摘目的:研究莲子壳中的黄酮类化学成分及抗氧化活性。方法:莲子壳的60%乙醇提取物经过大孔树脂初步分离之后,采用Toyopearl HW-40S凝胶柱进一步分离得到了6个组分(LF-F1~LF-F6),再采用高效液相以及液质联用系统对其中的组分2(LF-F2)组成及结构进行分析,并采用化学发光法等方法研究了LF-F2的抗氧化活性。结果:莲子壳黄酮粗提物中总黄酮为94.1%;LF-F2中黄酮甙元是由槲皮素、杨梅黄酮、山奈酚、异鼠李素等组成的。LF-F2对超氧阴离子自由基、羟自由基以及对双氧水的清除作用的IC50分别为420、40、0.6μg/ml。结论:从莲子壳中鉴定出LF-F2中有芦丁存在。LF-F2具有很好的抗氧化效果,并存在剂量效应关系。 | 黄迪惠 胡崇琳 Husam M Credy 谢笔钧 何慧 杨尔宁 | 2009 | 食品科学2009，30，23： | 11 |
| 2 | Preparation of ZnO nanostructures by RF-magnetron sputtering on thermally oxidized porous silicon substrate for VOC sensing application显示文摘 | Al-Salman Husam S Abdullah M J | 2014 | Measurement2014，59，： | 1 |
| 3 | Pseudo-gamma ray volume from extended elastic impedance inversion for gas exploration显示文摘 | Husam M Patrick M | 2004 | The Leading Edge2004，23，： | 1 |
| 4 | Peroxidases inhibit NITRIC oxide(NO) dependent bronchodilation: Development of a model describing NO- peroxidase interactions 显示文摘 | Husam M Abu - soud Mohamed Y Khassawneh Ju - Tae Sohn | 2001 | Biochemistry2001，40，11： | 1 |
| 5 | From intelligent to smart cities 显示文摘 | DEAKIN M HUSAM A W | 2011 | In- telligent Buildings International2011，3，3： | 1 |
| 6 | Immune microenvironment of medulloblastoma:The association between its molecular subgroups and potential targeted immunotherapeutic receptors显示文摘Medulloblastoma(MB)is considered the commonest malignant brain tumor in children.Multimodal treatments consisting of surgery,radiation,and chemotherapy have improved patients’survival.Nevertheless,the recurrence occurs in 30%of cases.The persistent mortality rates,the failure of current therapies to extend life expectancy,and the serious complications of non-targeted cytotoxic treatment indicate the need for more refined therapeutic approaches.Most MBs originating from the neurons of external granular layer line the outer surface of neocerebellum and responsible for the afferent and efferent connections.Recently,MBs have been segregated into four molecular subgroups:Wingless-activated(WNT-MB)(Group 1);Sonichedgehog-activated(SHH-MB)(Group 2);Group 3 and 4 MBs.These molecular alterations follow specific gene mutations and disease-risk stratifications.The current treatment protocols and ongoing clinical trials against these molecular subgroups are still using common chemotherapeutic agents by which their efficacy have improved the progression-free survival but did not change the overall survival.However,the need to explore new therapies targeting specific receptors in MB microenvironment became essential.The immune microenvironment of MBs consists of distinctive cellular heterogeneities including immune cells and none-immune cells.Tumour associate macrophage and tumour infiltrating lymphocyte are considered the main principal cells in tumour microenvironment,and their role are still under investigation.In this review,we discuss the mechanism of interaction between MB cells and immune cells in the microenvironment,with an overview of the recent investigations and clinical trials. | Maher Kurdi Nasser Mulla Husam Malibary Ahmed K Bamaga Motaz M Fadul Eyad Faizo Sahar Hakamy Saleh Baeesa | 2023 | World Journal of Clinical Oncology2023，14，3： | 0 |
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