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| 1 | Is there a role for systemic targeted therapy after surgical treatment for metastases of renal cell carcinoma?显示文摘Metastatic renal cell carcinoma(m RCC) is a challenging disease. Despite the new targeted therapies, complete remissions occur only in 1%-3% of the cases, and the most effective first-line treatment drugs have reached a ceiling in overall survival(ranging from 9 to 49 mo). Metastasectomy remains to be the only curative option in most patients with m RCC. Prognostic nomograms have been recently published, so we have tools to classify patients in risk groups, allowing us to detect the cases with the higher risk of recurrence after metastasectomy. Although sparse, there is some evidence of effectiveness of neoadjuvant targeted therapy before metastasectomy; but with an increase in surgical complications due to the effects of these new drugs in tissue healing. We have aimed to answer the question: Is there a role for systemic targeted therapy after surgical treatment for metastases of renal cell carcinoma? We have made a search in Pubmed database. As far as we know, evidence is low and it's based in case reports and small series of patients treated with adjuvant drugs after neoadjuvant therapy plus metastasectomy in cases of partial response to initial systemic treatment. Despite the limitations and high risk of bias, promising results and cases with longterm survival with this approach have been described. Two ongoing clinical trials may answer the question that concerns us. | Adrian Husillos Alonso Manuel Carbonero García Carmen González Enguita | 2015 | World Journal of Nephrology2015，4，2： | 3 |
| 2 | Collecting duct renal cell carcinoma显示文摘 | Husillos A Herranz-Amo F Subird D | 2011 | Actas Urol Esp2011，35，6： | 1 |
| 3 | Villous ad-enoma in augmentation colocystoplasty asociated to infiltrating urotelial cancer in bladder remanent显示文摘 | Husillos Alonso A SubiráRíos D Molina Escudero R | | 0，，： | 1 |
| 4 | The effect of using thermally dried sewage sludge as an alternative fuel on Portland cement clinker production显示文摘 | Husillos Rodríguez N Martínez Ramírez S Blanco Varela MT | 2013 | Journal of Cleaner Production2013，52，： | 1 |
| 5 | Reverse logistics, stakeholders' influence, organizational slack, and managers' posture 显示文摘 | alvarez - Gil M J Berrone P Husillos F J Lado N | 2007 | Journal of Business Research2007，60，5： | 1 |
| 6 | Evaluation of spray-dried sludge from drink-ing water treatment plants as a prime material for clinker manufacture显示文摘 | Husillos Rodr′?guez N Mart′?nez-Ram′?rez S Blanco-Varela M T | | 0，，2： | 1 |
| 7 | Re-use of drinking water treatment plant sludge:Characterization and technologi- cal behaviour of cement mortars with atomized sludge additions显示文摘 | N Husillos Rodriguez S Martfnez Ramirez M T Blanco Varela | | 0，，： | 1 |
| 8 | Reverse Logistics,Stakeholders' Influence,Organizational Slack,and Managers' Posture显示文摘 | (A)lvarez-Gil M.J Berrone P Husillos F.J | | 0，，05： | 1 |
| 9 | Reverse Logistics, Stakeholders' Influence, Organizational Slack, and Managers' Posture 显示文摘 | M Jos Alvarez-Gil Pascual Berrone F Javier Husillos Nora Lado | 2007 | Journal of Business Research2007，60，5： | 1 |
| 10 | The institutionalisation of unaccountability : Loading the dice of corporate social responsibility discourse 显示文摘 | Archel P Husillos J Spence C | 2011 | Accounting Organizations and Society2011，36，6： | 1 |
| 11 | Collec ring duct renal cell carcinoma 显示文摘 | Husillos A Herranz-Amo F Subira D | 2011 | Actas Urol Esp2011，35，6： | 1 |
| 12 | The effect of using thermally dried sewage sludge as an alternative fuel on Portland cement clinker production显示文摘 | Nuria Husillos Rodríguez Sagrario Martínez-Ramírez María Teresa Blanco-Varela Shane Donatello Manel Guillem Joan Puig Carla Fos Enric Larrotcha Josep Flores | 2013 | Journal of Cleaner Production2013，，： | 1 |
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