|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Association between thrombotic risk factors and extent of fibrosis in patients with non-alcoholic fatty liver diseases显示文摘AIM: To evaluate the prevalence of genetic and acquired prothrombotic risk factors and their association with the extent of fibrosis and fatty infiltration in patients with non-alcoholic fatty liver disease (NAFLD).METHODS: Forty-four patients with chronic hepatitis (28 men and 16 women, with mean age of 45±11 and 49±12 years, respectively) constituted the patient population of this study. The groups were divided as follows: 15 patients with fatty liver (FL); 15 with non-alcoholic steatohepatitis (NASH); 14 with chronic viral hepatitis (CH) diagnosed by histology and liver technetium scan or ultrasound; and 10 healthy individuals. Thrombophilic, coagulation factors and genetic mutations were diagnosed by standard hemostatic and molecular coagulation assays.RESULTS: Activated protein C (APC) resistance and protein S were the most prevalent thrombotic risk factors (6% and 10% in NAFLD vs 21% and 14% in CH; P<0.01 and P<0.05, respectively). One thrombotic risk factor was identified in 41% of patients (23% mild fibrosis, 18% severe fibrosis) and two thrombotic risk factors in 6% of patients with NAFLD and severe fibrosis. While no differences in APC ratio, lupus anticoagulant, fibrinogen, factor V Leiden,prothrombin, and MTHFR mutation were found. Protein S levels were significantly lower in NASH patients than in patients with FL alone (92±19 vs106±2, P<0.01). Protein C levels were markedly higher in patients with NAFLD and mild or severe fibrosis as compared to the patients with CH, respectively (128±40 vs96±14, P<0.001 or 129±36 vs 88±13, P<0.01).CONCLUSION: Up to 46% of patients with NAFLD may have thrombotic risk factors, and the presence of thrombotic risk factors is correlated with the extent of hepatic fibrosis,suggesting a crucial role of the coagulation system in the pathogenesis of hepatic fibrosis. | N Assy I Bekirov Y Mejritsky L Solomon S Szvalb O Hussein | 2005 | World Journal of Gastroenterology2005，11，37： | 3 |
| 2 | Synthesis and Anfimicrobial Activity of Certain New 1,2,4- Triazolo pyrimidine Derivatives 显示文摘 | MOSTAFA Y A H HUSSEIN M A RADWAN A A | 2008 | Arch Pharmacal Res2008，31，3： | 1 |
| 3 | TSRG cryptosystem显示文摘 | Dakroury Y Badr A | 2003 | Design and Implementation2003，2，2： | 1 |
| 4 | Effects ofphosphodiesterase - 5 inhibitor on ischemic kidney injury duringnephron sparing surgery : quantitative assessment by NGAL andKIM-1 显示文摘 | Lahoud Y Hussein 0 Shalabi A | 2015 | World J Urol2015，33，12： | 1 |
| 5 | High postnatal oxidative stress in neonatal cysticperiventricular leukomalacia显示文摘 | Kakita H Hussein MH Yamada Y Henmi H Kato S Koba-yashi S | 2009 | Brain Dev2009，31，9： | 1 |
| 6 | Glut-1 expres- sion correlates with basal-like breast cancer 显示文摘 | Hussein Y R Bandyopadhyay S Semaan A | 2011 | Transl Oncol2011，4，6： | 1 |
| 7 | Quantitative Serum Glycomics of Esophageal Adenocarcinoma and Other Esophageal Disease Onsets (dagger)显示文摘 | Mechref Y Hussein A Bekesova S | 2009 | J Proteome Res2009，8，6： | 1 |
| 8 | Doppler assessment of brachial artery flow as a measure of endothelial dysfunction in pediatric chronic renalfailure 显示文摘 | Hussein G Bughdady Y Kandil ME | 2008 | Pediatr Nephrol2008，23，11： | 1 |
| 9 | Simultaneous determination of phosphate and silicate by first - deriva- tive spectrophotometry显示文摘 | El - SAYED A Y HUSSEIN Y Z MOHAMMED M A | 2001 | Analyst2001，10，126： | 1 |
| 10 | Factors affecting germination and emergence of dame's rocket(Hesperis matronalis)显示文摘 | Susko D J Hussein Y | 2008 | Weed Science2008，56，： | 1 |
| 11 | 显示文摘 | Hussein Z B Ming C Y Zainal Z | 2000 | Mater Sci Lett2000，19，10： | 1 |
| 12 | Clomiphene administration for cases of nonobstructive azoospermia:a muhicenter study显示文摘 | Hussein A Ozgok Y Ross L | 2005 | J An- drol2005，26，6： | 1 |
| 13 | Dye-interleaved nanocomposite: Evan's Blue in the lamella of Mg-Al-layered double hydroxide 显示文摘 | Hussein M Z Asmah H Y Lai M P | 2004 | Dyes and Pigments2004，63，： | 1 |
| 14 | Functionalized-carbon nanotube supported electrocatalysts and buckypaperbased biocathodes for glucose fuel cell applications显示文摘 | Hussein L Feng Y J Aonso-Vante N | 2011 | Electrochim Acta2011，56，22： | 1 |
| 15 | Doppler assessment of brachial artery flow as a measure of endothelial dysfunction in pediatric chronic renal failure 显示文摘 | Hussein G Bughdady Y Kandil ME | 2008 | Pediatr Nephrol2008，23，11： | 1 |
| 16 | Transradial complex left main trifurcation intervention显示文摘 | HUSSEIN H FANG H Y WU C J | 2010 | Catheter Cardiovasc Interv2010，76，5： | 1 |
| 17 | Evaluation of multicast routing algorithm for real-time communication on high-speed networks显示文摘 | Hussein F Douglas S Viniotis Y | 1997 | IEEE Journal on Selected Areas in Communications1997，15，3： | 1 |
| 18 | LDH-in- tercalated D-gluconate: generation of a new food additive- inorganic nanohybrid compound 显示文摘 | Ghotbi M Y Hussein M Z Yahaya A H | 2009 | J Phys Chem Sol- ids2009，711，6： | 1 |
| 19 | Cultivation of Arllirospira(Spirulina)platensis using confectionary wastes for aquaculture feeding显示文摘 | El-Kassas H Y Heneash A M M Hussein N R | 2015 | Journal of Genetic Engineering & Biotech- nology2015，13，2： | 1 |
| 20 | Effect of different levels of energy on carcass composition and meat quality of male black goats kids显示文摘 | Abdullah Y Abdullah Hussein S | 2007 | Livestock Science2007，107，1： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员