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1Celiac disease serology in patients with different pretest probabilities: Is biopsy avoidable?显示文摘AIM: To establish the diagnostic performance of sev-eral serological tests, individually and in combination, for diagnosing celiac disease (CD) in patients with different pretest probabilities, and to explore potential se- rological algorithms to reduce the necessity for biopsy. METHODS: We prospectively performed duodenal biopsy and serology in 679 adults who had either high risk (n = 161) or low risk (n = 518) for CD. Blood samples were tested using six assays (enzyme-linked immunosorbent assay) that detected antibodies to tissue transglutaminase (tTG) and deamidated gliadin peptide (DGP). RESULTS: CD prevalence was 39.1% in the high-risk population and 3.3% in the low-risk group. In high-risk patients, all individual assays had a high diagnostic efficacy [area under receiving operator characteristic curves (AU ROC): 0.968 to 0.999]. In contrast, assays had a lower diagnostic efficacy (AU ROC: 0.835 to 0.972) in the low-risk group. Using assay combinations, it would be possible to reach or rule out diagnosis of CD without biopsy in 92% of cases in both pretest populations. We observed that the new DGP/tTG Screen assay resulted in a surplus compared to more conventional assays in any clinical situation. CONCLUSION: The DGP/tTG Screen assay could be considered as the best initial test for CD. Combinations of two tests, including a DGP/tTG Screen, might be able to diagnose CD accurately in different clinical scenarios making biopsy avoidable in a high proportion of subjects.Emilia Sugai María L Moreno Hui J Hwang Ana Cabanne Adriana Crivelli Fabio Nach-man Horacio Vázquez Sonia Niveloni Julio Argonz Roberto Mazure Graciela La Motta María E Caniggia Edgardo Smecuol Néstor Chopita Juan C Gómez Eduardo Maurińo Julio C Bai 2010World Journal of Gastroenterology2010,16,25:4
2Stock assessment of yellow croaker in the Yellow Sea and the East China Sea显示文摘Hwang B N 1977Bull Fish Res1977,,17:1
3Comparison of ecotourism policies and implications for China's ecotourism development 显示文摘Wang S Heo J Yamada N Hwang S T 2009Journal of China Tourism Research2009,5,3:1
4Water-soluble characteristics of chlorine in char derived from municipal solid wastes显示文摘Hwang I H Matsuto T Tanaka N 2006Waste Management2006,26,6:1
5C-terminal deletion mutant of pokeweed antiviral protein inhibits viral infection but does not depurinate host ribosomes 显示文摘Tumer N E Hwang D J 1997Proc Natl Acad Sci USA1997,94,8:1
6Synthesis, characterization, and electroluminescence of new conjugated polyfluorene derivatives containing various dyes as comonomers 显示文摘CHO N S HWANG D H JUNG B J 2004Macromolecules2004,37,14:1
7Fast and automatic video object segmentation and tracking for content-based applications 显示文摘KIM C HWANG J N 2002IEEE Trans on Circuits Syst Video Technol2002,12,2:1
8The Cournot competition in the spatial equilibrium model显示文摘Yang C W Hwang M J Sohng S N 2002Energy Economics2002,24,2:1
9Induced growth ofBG-1 ovarian cancer cells by 17(3-estradiol or various endocrinedisrupting chemicals was reversed by resveratrol viadownregulation of cell cycle progression显示文摘Kang N H Hwang K A Kim T H 2012Mol Med Report2012,6,1:1
10Investigation of factors af- fecting the diffusion of mobile telephone services: An empirical analysis for Vietnam显示文摘Hwang J Cho Y Long N V 2009Telecommunications Policy2009,33,:1
11A potential field approach to path planning显示文摘HWANG Y K NARENDRA N 1992IEEE Transactions Robotics and Automa- tion1992,8,:1
12Ground response during pile driving 显示文摘Hwang J H Liang N Chen C H 2001Journal of Geotechnical and Geoenviron- mental Engineering2001,127,11:1
13Antioxidative effect of chitosan on chronic carbon tetrachloride induced he- patic injury in rats显示文摘JEON T I HWANG S G PARK N G 2003Toxicology2003,187,:1
14Design Consideration for Durability of High-performance Concrete显示文摘Chang P K Peng Hwang Y N 2001Cement and Concrete Composites2001,23,45:1
15Synergistic inhibition of LDL oxidation by phytoestrogens and ascorbic acid 显示文摘Hwang J Sevanian A Hodis H N 2000Free Radical Biology & Medicine2000,29,1:1
16An analysis of factors affecting price volatility of the US oil market显示文摘Yang C W Hwang M J Huang B N 2002Energy Economics2002,24,2:1
17Physical structure and expression of alkBA encoding alkane hydroxy- lase and rubredoxin reductase from Pseudomonas maltophilia 显示文摘Lee N R Hwang M O Jung G H Kim Y S Min K H 1996Biochem Biophys Res Commun1996,218,1:1
18Efficiency decomposition in two - stage data envelopment analysis: an application to non-life insurance companies in Taiwan 显示文摘Kao C Hwang S N 2008European Journal of Operational Research2008,185,1:1
19Peroxiredoxin I is an indicator of microglia activation and protects against hydrogen peroxide-mediated microglial death显示文摘Kim S U Hwang C N Sun H N 2008Biol Pharm Bull2008,31,5:1
20Non linear constitutive relations for magnetostrictive materials显示文摘Wan Y P Fang D N Hwang K C 2003International Journal of Non-Linear Mechanics2003,38,7:1
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