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| 1 | Design and performance simulation of a molecular Doppler wind lidar显示文摘A mobile molecular Doppler wind lidar at an eye-safe wavelength of 355 nm based on double-edge technique is being built in Hefei (China) for wind measurement from 10-to 40-km altitude. The structure of this lidar system is described. A triple Fabry-Perot etalon is employed as a frequency discriminator whose parameters are optimized. The receiver system is designed to achieve compactness and stability by putting in a standard 19-inch socket bench. Simulation results show that within the wind speed dynamic range of ±100 m/s, the horizontal wind errors due to noise are less than 1 m/s below 20-km altitude for 100-m vertical resolution, and less than 5.5 m/s from 20 km up to 40 km for 500-m vertical resolution with 400-mJ laser energy, 30-min temporal resolution, and a 45-cm aperture telescope. | 沈法华 Hyunki Cha 董吉辉 Dukhyeon Kim 孙东松 Sung Ok Kwon | 2009 | Chinese Optics Letters2009，7，7： | 17 |
| 2 | Endoscopic and clinicopathologic characteristics of early gastric cancer with high microsatellite instability显示文摘AIM:To investigate endoscopic and clinicopathologic characteristics of early gastric cancer (EGC) according to microsatellite instability phenotype.METHODS:Data were retrospectively collected from a single tertiary referral center.Of 981 EGC patients surgically treated between December 2003 and October 2007,73 consecutive EGC patients with two or more microsatellite instability (MSI) mutation [high MSI (MSI-H)] and 146 consecutive EGC patients with one or no MSI mutation (non-MSI-H) were selected.The endoscopic and clinicopathologic features were compared between the MSI-H and non-MSI-H EGC groups.RESULTS:In terms of endoscopic characteristics,MSI-H EGCs more frequently presented with elevated pattern (OR 4.38,95% CI:2.40-8.01,P < 0.001),moderateto-severe atrophy in the surrounding mucosa (OR 1.91,95% CI:1.05-3.47,P = 0.033),antral location (OR 3.99,95% CI:2.12-7.52,P < 0.001) and synchronous lesions,compared to non-MSI-H EGCs (OR 2.65,95% CI:1.16-6.07,P = 0.021).Other significant clinicopathologic characteristics of MSI-H EGC included predominance of female sex (OR 2.77,95% CI:1.53-4.99,P < 0.001),older age (> 70 years) (OR 3.30,95% CI:1.57-6.92,P = 0.002),better histologic differentiation (OR 2.35,95% CI:1.27-4.34,P = 0.007),intestinal type by Lauren classification (OR 2.34,95% CI:1.15-4.76,P = 0.019),absence of a signet ring cell component (OR 2.44,95% CI:1.02-5.86,P = 0.046),presence of mucinous component (OR 5.06,95% CI:1.27-20.17,P = 0.022),moderate-to-severe lymphoid stromal reaction (OR 3.95,95% CI:1.59-9.80,P = 0.003),and co-existing underlying adenoma (OR 2.66,95% CI:1.43-4.95,P = 0.002).CONCLUSION:MSI-H EGC is associated with unique endoscopic and clinicopathologic characteristics including frequent presentation in protruded type,co-existing underlying adenoma,and synchronous lesions. | Jaehoon Jahng Young Hoon Youn Kwang Hyun Kim Junghwan Yu Yong Chan Lee Woo Jin Hyung Sung Hoon Noh Hyunki Kim Hoguen Kim Hyojin Park Sang In Lee | 2012 | World Journal of Gastroenterology2012，18，27： | 6 |
| 3 | Differential diagnosis between gallbladder adenomas and cholesterol polyps on contrast-enhanced harmonic endoscopic ultrasonography显示文摘 | Chan Hyuk Park Moon Jae Chung Tak Geun Oh Jeong Youp Park Seungmin Bang Seung Woo Park Hyunki Kim Ho Kyoung Hwang Woo Jung Lee Si Young Song | 2013 | Surgical Endoscopy2013，，4： | 2 |
| 4 | The design and analysis of AVTMR (all voting triple modular redundancy) and dual-duplex system 显示文摘 | Hyunki Kim Hyeunate Lee Keyseo Lee | 2005 | Reliability Engineering and System Safety (S0951-8320)2005，88，3： | 1 |
| 5 | Signet ring cell mixed histology may show more aggressive behavior than other histologies in early gastric cancer显示文摘 | Cheal Wung Huh Da Hyun Jung Jie‐Hyun Kim Yong Chan Lee Hyunki Kim Hoguen Kim Sun Och Yoon Young Hoon Youn Hyojin Park Sang In Lee Seung Ho Choi Jae‐Ho Cheong Sung Hoon Noh | 2012 | Oncol2012，，2： | 1 |
| 6 | Contaminated open fracture and crush injury: a murine model显示文摘Modern warfare has caused a large number of severe extremity injuries, many of which become infected. In more recent conflicts, a pattern of co-infection with Acinetobacter baumannii and methicillin-resistant Staphylococcus aureus has emerged. We attempted to recreate this pattern in an animal model to evaluate the role of vascularity in contaminated open fractures. Historically, it has been observed that infected bones frequently appear hypovascular, but vascularity in association with bone infection has not been examined in animal models. Adult rats underwent femur fracture and muscle crush injury followed by stabilization and bacterial contamination with A. baumannii complex and methicillin-resistant Staphylococcus aureus.Vascularity and perfusion were assessed by micro CT angiography and SPECT scanning, respectively, at 1, 2 and 4 weeks after injury. Quantitative bacterial cultures were also obtained. Multi-bacterial infections were successfully created, with methicillin-resistant S. aureus predominating. There was overall increase in blood flow to injured limbs that was markedly greater in bacteria-inoculated limbs. Vessel volume was greater in the infected group. Quadriceps atrophy was seen in both groups, but was greater in the infected group. In this animal model, infected open fractures had greater perfusion and vascularity than non-infected limbs. | Shawn R Gilbert Justin Camara Richard Camara Lynn Duffy Ken Waites Hyunki Kim Kurt Zinn | 2015 | Bone Research2015，3，1： | 1 |
| 7 | Potential Contribution of Preoperative Neoadjuvant Concurrent Chemoradiation Therapy on Margin-Negative Resection in Borderline Resectable Pancreatic Cancer显示文摘 | Chang Moo Kang Yong Eun Chung Jeong Youp Park Jin Sil Sung Ho Kyoung Hwang Hye Jin Choi Hyunki Kim Si Young Song Woo Jung Lee | 2012 | Journal of Gastrointestinal Surgery2012，，3： | 1 |
| 8 | Differential diagnosis between gallbladder adenomas and cholesterol polyps on contrast-enhanced harmonic endoscopic ultrasonography显示文摘 | Chan Hyuk Park Moon Jae Chung Tak Geun Oh Jeong Youp Park Seungmin Bang Seung Woo Park Hyunki Kim Ho Kyoung Hwang Woo Jung Lee Si Young Song | 2013 | Surgical Endoscopy2013，，4： | 1 |
| 9 | High Expression of AT-Rich Interactive Domain 3A (ARID3A) is Associated with Good Prognosis in Colorectal Carcinoma显示文摘 | Meiying Song Hyunki Kim Won Kyu Kim Sung Pil Hong Cheolju Lee Hoguen Kim | 2014 | Annals of Surgical Oncology2014，，4： | 1 |
| 10 | Efficient dynamic time warping for 3D handwriting recognition using gyroscope equipped smartphones 显示文摘 | Kim Dae-Won Lee Jaesung Lim Hyunki | 2014 | Expert Systems with Applications2014，41，11： | 1 |
| 11 | Single patient classifier as a prognostic biomarker in pT1N1 gastric cancer:Results from two large Korean cohorts显示文摘Objective:Benefits of adjuvant treatment in pT1 N1 gastric cancer(GC)remain controversial.Additionally,an effective biomarker for early GC is the need of the hour.The prognostic and predictive roles of single patient classifier(SPC)were validated in stageⅡ/ⅢGC.In this study,we aimed to elucidate the role of SPC as a biomarker for pT1 N1 GC.Methods:The present retrospective biomarker study(NCT03485105)enrolled patients treated for pT1 N1 GC between 1996 and 2012 from two large hospitals(the Y cohort and S cohort).For SPC,mRNA expression of four classifier genes(GZMB,WARS,SFRP4 and CDX1)were evaluated by real-time reverse transcription-polymerase chain reaction assay.The SPC was revised targeting pT1 stages and the prognosis was stratified as high-and lowrisk group by the expression of SFRP4,a representative epithelial-mesenchymal transition marker.Results:SPC was evaluated in 875 patients(n=391 and 484 in the Y and S cohorts,respectively).Among 864 patients whose SPC result was available,41(4.7%)patients experience GC recurrence.According to revised SPC,254(29.4%)patients were classified as high risk[123(31.5%)and 131(27.1%)in the Y and S cohorts,respectively].The high risk was related to frequent recurrence in both Y and S cohort(log-rank P=0.023,P<0.001,respectively),while there was no difference by GZMB and WARS expression.Multivariable analyses of the overall-cohort confirmed the high risk of revised SPC as a significant prognostic factor[hazard ratio(HR):4.402(2.293-8.449),P<0.001]of GC.A significant difference was not detected by SPC in the prognosis of patients in the presence and absence of adjuvant treatment(log-rank P=0.670).Conclusions:The present study revealed the revised SPC as a prognostic biomarker of pT1 N1 GC and suggested the use of the revised SPC for early-stage GC as like stageⅡ/Ⅲ. | Yoon Young Choi Eunji Jang Hyunki Kim Kyoung-Mee Kim Sung Hoon Noh Tae Sung Sohn Yong-Min Huh Ji Yeong An Jae-Ho Cheong | 2021 | Chinese Journal of Cancer Research2021，33，5： | 0 |
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