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38篇 您的检索式:作者名="Iain L"
    题名 作者 年代 出处 被引量
1A role of stretch-activated potassium currents in the regulation of uterine smooth muscle contraction显示文摘早熟的出生的率是惊人的并且威胁社会和世界范围的保健系统。早产在超过 50% 盒子导致早熟的出生。Preterm 出生说明婴儿病态和死亡的 three-quarters。在 34 星期怀孕期前熬过出生的孩子经常面对终生的残疾。为劳动正在想要的 preterm 的当前的处理。没有处理被发现了通常有效,任何一个都系统地没在 48 h 以外被评估。preterm 劳动的处理的新途径绝望地被需要。从我们的实验室的最近的研究建议子宫的肌肉是有不同于另外的光滑的肌肉的子宫的松驰的规定的唯一的分隔空间。这里,我们讨论最近的证据机械地激活的 2 毛孔钾隧道, TREK-1,可以贡献在子宫的光滑的肌肉和变体与人的劳动联系了的那 TREK-1 基因发信号的收缩松驰, preterm 劳动可以导致 preterm 劳动和它的可能的预防的更好的理解。Iain L O BUXTON Nathanael HEYMAN Yi-ying WU Scott BARNETT Craig ULRICH 2011Acta Pharmacologica Sinica2011,32,6:2
2A Reviewand Analysis of Current Computer-Aided Fixture DesignApproaches 显示文摘B O Y L E Iain R O N G Yiming B R O W N David C 2011Robotics and Computer-Integrated Manufacturiiig2011,27,1:1
3难治性类风湿关节炎的临床特点:一项国际问卷调查研究显示文摘目的尽管按照目前欧洲抗风湿联盟(EULAR)的推荐对类风湿关节炎(rheumatoid arthritis,RA)患者进行治疗,难治性RA患者的临床症状却仍然没有得到完全控制,目前EULAR指南主要关注的是RA的早期治疗和药物治疗。本研究的目的在于分析难治性RA患者的临床特点,以及在患者管理中需要探索然而现有EULAR指南并未涉及的问题。方法对多个国家的风湿科医生进行问卷调查,分析难治性RA的临床特点。问卷包括多选题以及开放性问题,从开放性问题的回答中发现需要进一步阐明的问题以及现有EULAR指南需要增加的内容。结果410名受访者完成了调查问卷,关于难治性RA的特点:50%受访者认为基于28个关节评估的疾病活动评分(disease activity score assessing 28 joints,DAS28)>3.2或存在疾病活动的征象;42%受访者认为疲劳是其特点;48%认为至少两种传统合成改变病情抗风湿药(DMARDs)以及使用至少两种生物制剂或靶向合成DMARDs治疗失败;89%认为糖皮质激素不能减量到5 mg/天或泼尼松不能减量到10 mg/天或同等剂量的其他激素。另外,现有EULAR指南中应增加合并症和关节外表现的干预以及多种药物联合治疗等重要内容。结论目前风湿科医生对难治性RA的定义有很大争议。难治性RA患者的很多重要问题目前EULAR指南中均没有涉及。Nadia MT Roodenrijs Maria J H de Hair Marlies C van der Goes Johannes WG Jacobs Paco MJ Welsing Désirée van der Heijde Daniel Aletaha Maxime Dougados Kimme L Hyrich Iain B McInnes Ulf Mueller-Ladner Ladislav Senolt Zoltan Szekanecz Jacob Mvan Laar Nagy Gyorgy 黄艳荣(译) 张卓莉(审校) 2019英国医学杂志中文版2019,22,2:1
4Angiostatin binds ATP synthase on the surface of human endothelial cells 显示文摘Tammy L Moser M Sharon Stack Iain Asplin 1999Proc Natl Acad Sci USA1999,96,6:1
5Effective leadership and decision-making in animal groups on the move显示文摘Iain D C Krause J Simon A L 2005Nature2005,433,7025:1
6Mechanistic and toxicity studies of the photocatalytic oxidation of microcystin-LR显示文摘 Linda A L Ben C 2002Journal of Photochemistry and Photobiology A:Chemistry2002,148,:1
7Mechanistic and oxideity studies of the photocatalytic oxidation of microcystin-LR 显示文摘IAIN L LINDA A L BEN C 2002Chemistry2002,148,13:1
8Mechanistic and toxicity studies of the photocatalytic oxidation of microcystin-LR显示文摘IAIN L LAWTON L A CORNISH B 2002J Phot Phot A:Chem2002,148,13:1
9Emerging cytokine targets in rheumatoid arthritis显示文摘Darren L Asquith Iain B McInnes 2007Current Opinion in Rheumatology2007,,3:1
10Ideal spatial adaptation by wavelet shrinkage 显示文摘DONOHO DAVID L JOHNSTONE IAIN M 1994Biometrika1994,81,3:1
11Mechanistic studies of the photocatalytic oxidation of microcystin-LR:an investigation of byproducts of the decomposition process显示文摘Iain L Linda AL Peter K JR 2003Environ Sci Technol2003,37,:1
12Adapting to un- known smoothness via wavelet shrinkage显示文摘DONOHO DAVID L JOHNSTONE IAIN M 1995Journal of the American Statistical Association1995,90,432:1
13A Role of Matrix Metalloproteinase-8 in Atherosclerosis显示文摘Ross C. Laxton Yanhua Hu Johan Duchene Feng Zhang Zhongyi Zhang Kit-Yi Leung Qingzhong Xiao Ramona S. Scotland Conrad P. Hodgkinson Katherine Smith Johann Willeit Carlos López-Otín Iain A. Simpson Stefan Kiechl Amrita Ahluwalia Qingbo Xu Shu Ye 2009Circulation Research2009,,9:1
14Pax7 activates myogenic genes by recruitment of a histone methyltransfcrase complex 显示文摘Iain W M Ishibashi J Grand F L 2008Nature Cell Biology2008,10,:1
15In search of optimal stocking regimes in semi-arid grazing lands: one size does not fit all显示文摘Bruce M C Iain J G Martin K L 2006Ecological economics2006,60,:1
16Mechanistic and toxicity studies of the photocatalytic oxidation of microcystin-LR显示文摘Iain L Linda A Lawton Ben Cornish 2002Journal of Photochemistry and Photobiology A:Chemistry2002,148,13:1
17Threshold Selection for Wavelet Shrinkage of Noisy Data 显示文摘David L Iain M 1994Proceedings of the 16th Annual International Conference of the IEEE1994,1,:1
18Adapting to unknown smoothness via wavelet shrinkage显示文摘Donoho D L Johnstone Iain M 1995Journal of the America Statistical Association1995,90,432:1
19Thermoregulatory behavior of the crayfish Procambarus clarkii in a burrow environment显示文摘Aaron L P Iain J M 2003Comparative Biochemistry and Physiology Part A2003,136,:1
20Summary of the 2008 BTS/SIGN British Guideline on the Management of Asthma 显示文摘Mark L Levya Mike Thomasb Iain R Smallc 2009Primary Care Respiratory Journal2009,181,:1
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