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| 1 | Diagnosis of gastrointestinal bleeding: A practical guide for clinicians显示文摘Gastrointestinal bleeding is a common problem encountered in the emergency department and in the primary care setting. Acute or overt gastrointestinal bleeding is visible in the form of hematemesis, melena or hematochezia. Chronic or occult gastrointestinal bleeding is notapparent to the patient and usually presents as positive fecal occult blood or iron deficiency anemia. Obscure gastrointestinal bleeding is recurrent bleeding when the source remains unidentified after upper endoscopy and colonoscopic evaluation and is usually from the small intestine. Accurate clinical diagnosis is crucial and guides definitive investigations and interventions. This review summarizes the overall diagnostic approach to gastrointestinal bleeding and provides a practical guide for clinicians. | Bong Sik Matthew Kim Bob T Li Alexander Engel Jaswinder S Samra Stephen Clarke Ian D Norton Angela E Li | 2014 | World Journal of Gastrointestinal Pathophysiology2014,5,4: | 13 |
| 2 | One hundred and seventy-eight consecutive pancreatoduodenectomies without mortality:role of the multidisciplinary approach显示文摘BACKGROUND:Pancreatoduodenectomy offers the only chance of cure for patients with periampullary cancers.This,however,is a major undertaking in most patients and is associated with a significant morbidity and mortality.A multidisciplinary approach to the workup and follow-up of patients undergoing pancreatoduodenectomy was initiated at our institution to improve the diagnosis,resection rate,mortality and morbidity.We undertook the study to assess the effect of this approach on diagnosis,resection rates and short-term outcomes such as morbidity and mortality.METHODS:A prospective database of patients presenting with periampullary cancers to a single surgeon between April 2004 and April 2010 was reviewed.All cases were discussed at a multidisciplinary meeting comprising surgeons,gastroenterologists,radiologists,oncologists,radiation oncologists,pathologists and nursing staff.A standardized investigation and management algorithm was followed.Complications were graded according to the Clavien-Dindo classification.RESULTS:A total of 295 patients with a periampullary lesion were discussed and 178 underwent pancreatoduodenectomy (resection rate 60%).Sixty-one patients (34%) required either a vascular or an additional organ resection.Eighty-nine patients experienced complications,of which the commonest was blood transfusion (12%).Thirty-four patients (19%) had major complications,i.e.grade 3 or above.There was no in-hospital,30-day or 60-day mortality.CONCLUSIONS:Pancreatoduodenectomy can safely be performed in high-volume centers with very low mortality.The surgeon's role should be careful patient selection,intensive preoperative investigations,use of a team approach,and an unbiased discussion at a multidisciplinary meeting to optimize the outcome in these patients. | Jaswinder S Samra Raul Alvarado Bachmann Julian Choi Anthony Gill Michael Neale Vikram Puttaswamy Cameron Bell Ian Norton Sarah Cho Steven Blome Ritchie Maher Sivakumar Gananadha Thomas J Hugh | 2011 | Hepatobiliary & Pancreatic Diseases International2011,10,4: | 8 |
| 3 | Development of a 100 J,10 Hz laser for compression experiments at the High Energy Density instrument at the European XFEL显示文摘In this paper we review the design and development of a 100 J, 10 Hz nanosecond pulsed laser, codenamed DiPOLE100 X,being built at the Central Laser Facility(CLF). This 1 kW average power diode-pumped solid-state laser(DPSSL) is based on a master oscillator power amplifier(MOPA) design, which includes two cryogenic gas cooled amplifier stages based on DiPOLE multi-slab ceramic Yb:YAG amplifier technology developed at the CLF. The laser will produce pulses between 2 and 15 ns in duration with precise, arbitrarily selectable shapes, at pulse repetition rates up to 10 Hz, allowing real-time shape optimization for compression experiments. Once completed, the laser will be delivered to the European X-ray Free Electron Laser(XFEL) facility in Germany as a UK-funded contribution in kind, where it will be used to study extreme states of matter at the High Energy Density(HED) instrument. | Paul Mason Saumyabrata Banerjee Jodie Smith Thomas Butcher Jonathan Phillips Hauke Hoppner Dominik Moller Klaus Ertel Mariastefania De Vido Ian Hollingham ANDrew Norton Stephanie Tomlinson Tinesimba Zata Jorge Suarez Merchan Chris Hooker Mike Tyldesley Toma Toncian Cristina HernANDez-Gomez Chris Edwards John Collier | 2018 | High Power Laser Science and Engineering2018,6,4: | 4 |
| 4 | Approaches to improve cultured pearl formation in Pinctada margaritifera through use of relaxation,antiseptic application and incision closure during bead insertion显示文摘 | Norton J H Lucas J S Ian T | 2000 | Aquaculture2000,184,: | 1 |
| 5 | Micro- structural design to reduce lipid oxidation in oil-inwater e- mulsions显示文摘 | Maryam Kargara Fotis Spyropoulos Ian T Norton | 2011 | Procedia Food Science2011,1,: | 1 |
| 6 | Neural network analysis of EUS images to differentiate between pancreatic malignancy and pancreatitis显示文摘 | Ian D. Norton Yi Zheng Maurits S. Wiersema James Greenleaf Jonathan E. Clain Eugene P. DiMagno | 2001 | Gastrointestinal Endoscopy2001,,5: | 1 |
| 7 | Formulation engineering of water in cocoa – Butter emulsion显示文摘 | Antonio Sullo Marcela Arellano Ian T. Norton | 2014 | Journal of Food Engineering2014,,: | 1 |
| 8 | A National comparison of surgical versus percutaneous drainage of pancreatic pseudocysts: 1997–2001显示文摘 | John M. Morton M.D. M.P.H. Alphonso Brown M.D. M.P.H. Joseph A. Galanko Ph.D. Jeffrey A. Norton M.D. Ian S. Grimm M.D. Kevin E. Behrns M.D | 2005 | Journal of Gastrointestinal Surgery2005,,1: | 1 |
| 9 | A National comparison of surgical versus percutaneous drainage of pancreatic pseudocysts: 1997–2001显示文摘 | John M. Morton M.D. M.P.H. Alphonso Brown M.D. M.P.H. Joseph A. Galanko Ph.D. Jeffrey A. Norton M.D. Ian S. Grimm M.D. Kevin E. Behrns M.D | 2005 | Journal of Gastrointestinal Surgery2005,,1: | 1 |
| 10 | A National comparison of surgical versus percutaneous drainage of pancreatic pseudocysts: 1997–2001显示文摘 | John M. Morton M.D. M.P.H. Alphonso Brown M.D. M.P.H. Joseph A. Galanko Ph.D. Jeffrey A. Norton M.D. Ian S. Grimm M.D. Kevin E. Behrns M.D | 2005 | Journal of Gastrointestinal Surgery2005,,1: | 1 |
| 11 | Acute extraluminal hemorrhage associated with EUS-guided fine needle aspiration: Frequency and clinical significance显示文摘 | Aboud Affi Enrique Vazquez-Sequeiros Ian D. Norton Jonathan E. Clain Maurits J. Wiersema | 2001 | Gastrointestinal Endoscopy2001,,2: | 1 |
| 12 | The impact of rheumatoid arthritis on quality-of-life assessed using the SF-36: A systematic review and meta-analysis显示文摘 | Faith Matcham Ian C. Scott Lauren Rayner Matthew Hotopf Gabrielle H. Kingsley Sam Norton David L. Scott Sophia Steer | 2014 | Seminars in Arthritis and Rheumatism2014,,: | 1 |
| 13 | Approaches to improve cultured pearl formation in Pinctada margaritifera through use of relaxation, antiseptic application and incision closure during bead insertion显示文摘 | John H Norton John S Lucas Ian Turner Robert J Mayer Raymond Newnham | 2000 | Aquaculture2000,,1: | 1 |
| 14 | Postpolypectomy lower GI bleeding: Descriptive analysis显示文摘 | Darius Sorbi Ian Norton Massimo Conio Rita Balm Alan Zinsmeister Christopher J. Gostout | 2000 | Gastrointestinal Endoscopy2000,,6: | 1 |
| 15 | A prospective study of EUS-guided celiac plexus neurolysis for pancreatic cancer pain显示文摘 | Naresh T. Gunaratnam Aruna V. Sarma Ian D. Norton Maurits J. Wiersema | 2001 | Gastrointestinal Endoscopy2001,,3: | 1 |
| 16 | 西印度构造演化及其对烃类显示意义综述显示文摘印度最大的油气聚集区位于西印度,具有独特的构造事件集中发生。中生代沿元古代活动带构造方向的裂谷作用形成了印度海岸的被动边缘盆地。Campanian期(83.5—70.6Ma),马达加斯加与印度发生分离,南北向正断层传播进入到Cambay Graben地区。在初始德干Reunion热点之上,晚Maastrichtian(70.6—65.5Ma)隆起在西北印度海岸产生了伸展应力场,形成盂买高断块。早古新世,德干溢流玄武岩喷发后,伸展在薄弱的地壳中继续,引起了孟买地堑和Surat坳陷沉降的加强、Seychelles微大陆从印度分离以及孟买高地上正断层的重新活动。孟买地堑和Surat(Danahu)坳陷在热沉降期间充填了富有机质页岩,在缓慢沉降的盂买台地上发育了始新-中新世浅水碳酸盐,海平面波动产生了次生孔隙的发育。晚第三纪成熟的Surat(Danahu)坳陷页岩生成烃类,运移至孟买高的碳酸盐储层。Canlpanian构造事件之后,Konkan—kerala和印度东海岸的较老盆地并未受到影响,缺乏有利的成藏要素是该地区的特点。 | Andrew M. Gombos William G. Powell Ian O. Norton 万玲(译) 万荣胜(校) | 2009 | 海洋地质2009,,4: | 0 |