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| 1 | Interleukin-1 beta induces the expression and production of stem cell factor by epithelial cells: crucial involvement of the PI-3K/mTOR pathway and HIF-1 transcription complex显示文摘在发炎和白血球过多症之间的潜在的交叉连接有一段时间被讨论了,但是支持这教义的试验性的证据是少见的。特别地,由煽动性的调停人理解为 proto-oncogenic 生长因素表情的潜在的 upregulation 负责的机制是重要的。这里,我们调查了高度煽动性的 cytokine interleukin-1 贝它的能力(IL-1β) 到导致干细胞因素(SCF ) 的生产,它是在造血的 myeloid 细胞的恶意的转变之上控制尖锐 myeloid 白血球过多症的前进的一个主要造血的生长因素。我们发现了那人的 IL-1β在 MCF-7 人的上皮的乳癌房间和那导致了 SCF 的表示 / 分泌物这个过程取决于组织缺氧可诱导的因素 1 (HIF-1 ) 抄写建筑群。我们也表明了 phosphatidylinositol-3 kinase (PI-3K ) 的一个关键角色 rapamycin (mTOR ) 的 /mammalian 目标在 IL-1β 的小径;导致的 HIF-1α在 MCF-7 房间的累积。重要地, mTOR 也被发现在 IL-1β 起一个作用;导致的 SCF 生产。而且,为 IL-1β 的积极关联的一个趋势;并且在健康人的施主的血浆的 SCF 层次被观察。总的来说,我们的结果表明那 IL-1β,它通常衔接天生、适应的免疫,通过 PI-3K/mTOR 小径和 HIF-1 抄写建筑群导致主要 haematopoietic/proleukaemic 生长因素 SCF 的生产。这些调查结果强烈支持在发炎和尖锐 myeloid 白血球过多症之间的串音。 | Rafal W Wyszynski Bernhard F Gibbs Luca Varani Daniela Iannotta Vadim V Sumbayev | 2016 | Cellular & Molecular Immunology2016,13,1: | 2 |
| 2 | Ownership structure, risk and performance in the European banking industry显示文摘 | Giuliano Iannotta Giacomo Nocera Andrea Sironi | 2007 | Journal of Banking and Finance2007,,7: | 2 |
| 3 | Ownership structure, risk and performance in the European banking industry 显示文摘 | Giuliano Iannotta Giacomo Nocera Andrea Sironi | 2007 | Journal of Banking & Finance2007,,31: | 1 |
| 4 | Methotrexate toxicity and efficacy during the consolidation phase in paediatric acute lymphoblastic leukaemia and MTHFR polymorphisms as pharmacogenetie determinants 显示文摘 | D'Angelo V Ramaglia M Iannotta A | 2011 | Cancer Chernother Pharmacol2011,68,: | 1 |
| 5 | Ownership Structure, Risk and Performance in the European Banking Industry 显示文摘 | Giuliano Iannotta Giacomo Nocera | 2007 | Journal of Banking and Finance2007,,7: | 1 |
| 6 | 显示文摘 | Iannotta F Fachinetti A | 1991 | Minerva Endocrinol1991,16,3: | 1 |
| 7 | Ownership Structure, Risk and Performance in the European Banking Industry 显示文摘 | IANNOTTA G NOCERA G SIRONI A | 2007 | Journal of Banking and Finance2007,31,7: | 1 |
| 8 | Vortex draws flight research forward 显示文摘 | Iannotta B | 2002 | Aerospace America2002,40,3: | 1 |
| 9 | In Vivo Phenotyping for the Early Detection of Drought Stress in Tomato显示文摘Drought stress imposes a major constraint over a crop yield and can be expected to grow in importance if the climate change predicted comes about.Improved methods are needed to facilitate crop management via the prompt detection of the onset of stress.Here,we report the use of an in vivo OECT(organic electrochemical transistor)sensor,termed as bioristor,in the context of the drought response of the tomato plant.The device was integrated within the plant’s stem,thereby allowing for the continuous monitoring of the plant’s physiological status throughout its life cycle.Bioristor was able to detect changes of ion concentration in the sap upon drought,in particular,those dissolved and transported through the transpiration stream,thus efficiently detecting the occurrence of drought stress immediately after the priming of the defence responses.The bioristor’s acquired data were coupled with those obtained in a high-throughput phenotyping platform revealing the extreme complementarity of these methods to investigate the mechanisms triggered by the plant during the drought stress event. | Michela Janni Nicola Coppede Manuele Bettelli Nunzio Briglia Angelo Petrozza Stephan Summerer Filippo Vurro Donatella Danzi Francesco Cellini Nelson Marmiroli Domenico Pignone Salvatore Iannotta Andrea Zappettini | 2019 | Plant Phenomics2019,1,1: | 1 |
| 10 | Methotrexate toxicity and^Gcacy during the consolidation phase in paediatric acute lymphoblas-tic leukaemia and MTHFR polymorphisms as pharmacogenetic determi-nants 显示文摘 | Dangelo V Ramaglia M Iannotta k | 2011 | Cancer Chemotker Pharmacol2011,68,: | 1 |
| 11 | Ownership structure, risk and performance in the european banking industry显示文摘 | Iannotta G Nocera G Sironi A | 2007 | Journal of Banking & Finance2007,31,7: | 1 |
| 12 | Market Discipline in the Banking Industry: Evidence from Spread Dispersion显示文摘 | Iannotta G | 2011 | European Journal of Finance2011,17,2: | 1 |
| 13 | Ownership structure,risk and performance in the european banking industry显示文摘 | Iannotta G Nocera G Sironi A | | 0,,07: | 1 |
| 14 | Market discipline in the banking industry: evidence from spread dispersion显示文摘 | Giuliano Iannotta | 2011 | The European Journal of Finance2011,,: | 1 |
| 15 | Testing for Opaqueness in the European Banking Industry: Evidence from Bond Credit Ratings显示文摘 | Giuliano Iannotta | 2006 | Journal of Financial Services Research2006,,3: | 1 |
| 16 | Sumo wrestles satellites into new orbits显示文摘 | IANNOTTA B | 2006 | Aerospace America2006,44,2: | 1 |
| 17 | SUMO显示文摘 | Iannotta B | | 0,,02: | 1 |
| 18 | The cross-section of mutual fund fee dispersion显示文摘 | Giuliano Iannotta Marco Navone | 2011 | Journal of Banking and Finance2011,,3: | 1 |
| 19 | SUMO wrestles satellites into new orbits显示文摘 | Iannotta B | 2006 | Aerospace America2006,,: | 1 |
| 20 | LC/ESI-MS/MS method for the identification and quantification of spinosad residues in olive oils显示文摘 | Benincasa C Perri E Iannotta N | | 0,,: | 1 |