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| 1 | Probiotic effects on intestinal fermentation patterns in patients with irritable bowel syndrome显示文摘AIM: To determine whether Lactobacillus casei strain Shirota (Yakult ) can alter small intestinal bacterial overgrowth (SIBO), as tested by the lactulose breath test, and whether this is associated with changes in symptoms in irritable bowel syndrome (IBS). METHODS: 18 patients with IBS (Rome Ⅱ criteria), who showed an early rise in breath hydrogen with lactulose (ERBHAL), consumed 65 mL of Yakult daily for 6 wk. Lactulose breath test was repeated at the end of the treatment period. Symptoms were recorded daily using a 10 cm visual analogue scale. RESULTS: 14 patients completed the study, 9 (64%) had reversal of ERBHAL, with the median time of f irst rise in breath hydrogen increasing from 45 to 75 min (P = 0.03). There was no signifi cant improvement in the symptom score with probiotic therapy, except for wind (P=0.04). Patients commencing with at least moderate symptoms and who no longer had ERBHAL at the end of treatment, showed improvement in the overall symptoms scores [median fi nal score 5.3 (IQR3.9-5.9), 55% reduction; n=6] to a greater extent than those who had had persisting ERBHAL [final score 6.9 (5.0-7.0), 12% reduction; n = 5; P = 0.18]. CONCLUSION: Yakult is effective in altering fermentation patterns in the small bowel, consistent with reducing SIBO. The loss of ERBHAL was associated with reduced symptoms. The true interpretation of these fi ndings awaits a randomised, controlled trial. | Jacqueline S Barrett Kim EK Canale Richard B Gearry Peter M Irving Peter R Gibson | 2008 | World Journal of Gastroenterology2008，14，32： | 16 |
| 2 | 从660 km边界地形推断地球不连续的化学分层显示文摘板块构造学说是固体地.球科学的基石,刻画了岩石圈的基本运动学特征,而地幔对流理论则为理解板块运动提供了动力学基础。然而长期以来,地幔对流模式的研究一直存在巨大的争议,分玻主要集中于全见幔对流和上下他幔分层对流两个模式。近年来还有一些学者提出了地混合对流模式的猜想,即一些区域地幔分层对流、其他区域上下他做整体对流。已有研究表明,温度异帯及化学异常均可造成大尺度(1000km)和中等尺度(100km)的间斷面起伏。 | 张宝华 Wu W Ni S Irving J C | 2019 | 矿物岩石地球化学通报2019，38，3： | 6 |
| 3 | Risk-adjustment in hepatobiliarypancreatic surgery显示文摘AIM: The present study evaluates the performance of the POSSUM, the American Society of Anesthetists (ASA),APACHE and Childs classification in predicting mortality and morbidity in hepatopancreaticobiliary (HPB) surgery.We describe especially the limitations and advantages of risk in stratifying the patients.METHODS: We investigated 177 randomly chosen patients undergoing eledive complex HPB surgery in a single institution with a total of 71 pre-operative and intra-operative risk factors.Primary endpoint was in-hospital mortality and morbidity.Ordered logistic regression analysis was used to identify individual predictors of operative morbidity and mortality.RESULTS: The operative mortality in the series was 3.95% .This compared well with the p-POSSUM and APACHE predicted mortality of 4.31% and 4.29% respectively. Postoperative complications amounted to 45% with 24 (13.6%)patients having a major adverse event. On multivariate analysis the pre-operative POSSUM physiological score (OR = 1.18,P = 0.009) was superior in predicting complications compared to the ASA (P = 0.108), APACHE (P = 0.117)or Childs classification (P = 0.136). In addition, serum sodium, creatinine, international normalized ratio (INR),pulse rate, and intra-operative blood loss were independent risk factors. A combination of the POSSUM variables and INR offered the optimal combination of risk factors for risk prognostication in HPB surgery.CONCLUSION: Morbidity for elective HPB surgery can be accurately predicted and applied in everyday surgical practice as an adjunct in the process of informed consent and for effective allocation of resources for intensive and high-dependency care facilities. | Hemant M Kocher Paris P Tekkis Palepu Gopal Ameet G Patel Simon Cottam Irving S Benjamin | 2005 | World Journal of Gastroenterology2005，11，16： | 3 |
| 4 | An audit of percutane- ous nephrolithotomy in the United Kingdom 显示文摘 | BAYLES A CHITALE S IRVING S | 2011 | British Journal of Medical and Surgical Urology2011，4，3： | 1 |
| 5 | Influence of Pb segregation on the deformation of nanocrystalline Al:Insights from molecular simulations显示文摘 | Jang S Urohit Y Irving D L | 2008 | Acta Mater2008，56，： | 1 |
| 6 | The role of acute and early HIV infection in the spread of HIV and implications for transmission prevention strategies in Lilongwe, Malawi: a modelling study显示文摘 | Kimberly A Powers Azra C Ghani William C Miller Irving F Hoffman Audrey E Pettifor Gift Kamanga Francis EA Martinson Myron S Cohen | 2011 | The Lancet . 2011 (9787)2011，，： | 1 |
| 7 | A three-component model of customer commitment to service providers显示文摘 | Bansal H S Irving G Taylor S F | 2004 | Journal of the Academy of Marketing Science2004，32，3： | 1 |
| 8 | Maintaining remission from ulcerative colitis 显示文摘 | Chaplin S Johnston E Irving P | 2015 | Prescriber2015，26，12： | 1 |
| 9 | A three-component model of customer to service providers显示文摘 | Bansal H S Irving P G Taylor S F | 2004 | Journal of the Academy of Marketing Science2004，32，3： | 1 |
| 10 | Unenhanced CT for theevaluation of acute ureteric colic:the essential pictorial guide 显示文摘 | KENNISH S J WAH T M IRVING H C | 2010 | Postgraduate Medical Journal2010，86，1017： | 1 |
| 11 | Transmission loss allocation through a modified Y-bus显示文摘 | Daniel J S Salgado R S Irving M R | 2005 | lEE Proceedings-Generation Transmission andDistribution2005，152，2： | 1 |
| 12 | Microcystic stromal tumor : a distinctive ovarian sex cord-stromal neoplasm characterized by FOXL2, SF-1, WT-1, Cyclin DI, and β-catenin nuclear expression and CTNNBI mutations 显示文摘 | Irving J A Lee C H Yip S | 2015 | Am J Surg Pathol2015，39，10： | 1 |
| 13 | Hypoxic Regulation of Nucleus Pulposus Cell Survival显示文摘 | Makarand VR Ernestina S Irving MS | 2010 | The American Journal of Patholo-gy2010，176，4： | 1 |
| 14 | Restoring coastal plants to improve global carbon storage:reaping what we sow 显示文摘 | IRVING A D CONNELL S D RUSSELL B D | 2011 | Plos One2011，6，18： | 1 |
| 15 | A genetic algorithm modeling framework and solution technique for short term optimal hydrothermal seheduling 显示文摘 | Orero S O Irving M R | 1998 | IEEE Trans on Power Systems1998，13，2： | 1 |
| 16 | Improving a templated-based classifier in a SAR automatic target recognition system by using 3-D target information 显示文摘 | Verbout S M Irving W W Hanes A S | 1993 | Lincoln Laboratory Journal1993，6，1： | 1 |
| 17 | Conditionally replicative adenovirus driven by the human telomerase promoter provides broadspectrum antitumor activity without liver toxicity显示文摘 | Irving J Wang Z Powell S | 2004 | Cancer Gene Ther2004，11，3： | 1 |
| 18 | Large scale unit commitment using a hybrid genetic algorithm显示文摘 | Orero S O Irving M R | 1997 | Electrical Power & Energy Systems1997，19，1： | 1 |
| 19 | Microscopic observation during logitudinal compression loading of single pulp fibers显示文摘 | Irving B S | 1986 | Tappi1986，69，7： | 1 |
| 20 | A Threecomponent Model of Customer Commitment to Service Providers 显示文摘 | H S Bansal P G Irving S F Taylor | 2004 | Journal of the Academy of Marketing Science2004，32，2： | 1 |
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