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| 1 | 尼可地尔经皮冠状动脉介入治疗(PCI)降低心肌损伤显示文摘背景尼可地尔作为辅助治疗药物,在缺血性心脏病患者的治疗中具有良好效果。本研究旨在评估尼可地尔选择性经皮冠状动脉治疗(PCI)后对心肌的保护作用。方法我们随机地将49个接受选择性PCI治疗的病人分为尼可地尔及对照这两组。PCI治疗前,尼可地尔组先静脉推注4mg尼可地尔,介入治疗后再以6mg每小时的量静脉滴注24小时。口服尼可地尔给药组持续给药直至接下来的冠状动脉造影(CAG)。PCI治疗前及PCI治疗后0、4、24及48小时分别采集各组静脉血样,检测肌酸激酶(CK)、肌酸激酶MB亚型(CK-MB)、肌钙蛋白Ⅰ(TnI)和肌红蛋白的量。通过对比治疗前后的脑室造影来评价左心室功能及左心室壁运动。结果 PCI治疗后24小时,尼可地尔组的心肌酶水平显著低于对照组;实验组及对照组的CK分别为78.1±34.9,117.4±137.9U/l,显著性P=0.0141,CK-MB为1.57±1.90,2.67±4.50U/l,显著性P=0.0485,TnI为0.37±0.55,0.86±1.65ng/ml,显著性P=0.0101。尼可地尔组的局部左心室壁运动在后期较对照组显著增强。结论尼可地尔能抑制选择性PCI治疗后心肌酶的水平,并在后期显著增强左心室壁的运动,表明尼可地尔可提高PCI治疗时对心肌的保护,降低因血管成形术造成的心肌损伤。 | Tsuyoshi Isono Hiroshi Kamihata Yasuo Sutani Masayuki Motohiro Satoshi Yamamoto Shiori Kyoui Yoshiji Iharada Kouji Kurimoto Katsuko Hara Hakuo Takahashi Toshiji Iwasaka 陈浩 | 2016 | 首都食品与医药2016，23，20： | 3 |
| 2 | BALLOON-BORNE MEASUREMENTS OF AEROSOL VERTICAL DISTRIBUTIONS OVER BEIJING DURING THE SUMMER AND AUTUMN OF 1993显示文摘The results of two balloon soundings during the summer and autumn of 1993 from the Xianghe Observation Stationare being utilized in a study of the temporal and spatial distribution of the atmospheric aerosols.The balloon,gondola,instrumentation and atmospheric conditions during the observation period are described.The temporal and spatialcharacteristics of aerosol concentration,size ratio,mixing ratio,and size distribution for both troposphere and strato-sphere are presented and analyzed. | 周军 谭锟 邵石生 龚知本 石广玉 郭建东 王标 张豹武 孙宝来 Yasunobu Iwasaka Masahiko Hayashi Masahiro Hase | 1994 | Acta meteorologica Sinica1994，8，4： | 3 |
| 3 | Aerosol optical properties derived from simultaneous sunphotometer and aureolemeter measurements in Lhasa显示文摘In order to obtain some aerosol properties in Tibetan Plateau atmosphere, simultaneous measurements of aerosols by use of a sunphotometer and an aureolementer were performed in the summer of 1998 in Lhasa(29.65°N, 91.13°E). Optical depth, volume size distribution and phase\|function of aerosols were obtained from the measurements. Religious activities can have an effect on optical depth in Lhasa. The daily average aerosol optical depth( λ =500 nm) is less than 0.2. The diurnal variations of aerosol optical depth are relatively small during the period of summer. The maximal value of the mode radius in the volume size distribution are about 0.4, 2.0 and 4.0μm. | BAI Yu\|bo\+1, SHI Guang\|yu\+\{1*\}, Koichi Tamura\+2, Takashi Shibata\+2, Yasunobu Iwasaka\+2, Kaneta Shin′ichi\+3, Takamura Tamio\+3 (1. State Key Laboratory of Numerical Modeling for Atmospheric Sciences and Geophysical Fluid Dynamics, Institute | 2000 | Journal of Environmental Sciences2000，12，4： | 2 |
| 4 | Effects of hyperglycemia and insulin therapy on high mobility group box 1 in endotoxin-induced acute lung injury in a rat model显示文摘 | HAGIWARA S IWASAKA H HASEGAWA A | 2008 | Crit Care Med2008，36，8： | 1 |
| 5 | GaAlAs(830 nm)low-level laser enhances peripheral endogenous opioid analgesia in rats显示文摘 | Hagiwara S Iwasaka H Okuda K | 2007 | Lasers Surg Med2007，39，10： | 1 |
| 6 | Usefulness of plasma brain natriuretic peptide levels in predicting dobutamine-indueed myocardial ischemia 显示文摘 | Asada J Tsuji H Iwasaka T | 2004 | Am J Cardiol2004，93，6： | 1 |
| 7 | Pre-Irradiation of blood by gallium aluminum arsenide(830 nm)low-level laser enhances peripheral endogenous opioid analgesia in rats显示文摘 | Hagiwara S Iwasaka H Hasegawa A | 2008 | Anesth Analg2008，107，3： | 1 |
| 8 | Telomerase activation in cervical neoplasia显示文摘 | Iwasaka T Zheng Ps Yo Koyama M | 1998 | Obetet Gynecol1998，91，2： | 1 |
| 9 | Usefulness of plasma brain natriuretic peptide levels in predicting dobutamine-induced myocardial ischemia 显示文摘 | Asada J Tsuji H Iwasaka T | 2004 | Am J Cardiol2004，93，6： | 1 |
| 10 | Nitrate and sulfate in individual Asian dust-storm particles in t3eijing, China in Spring of 1995 and 1996 显示文摘 | Zhang D Iwasaka Y | 1999 | Atmospheric Environment1999，33，： | 1 |
| 11 | Th1/Th2 balance in systemic inflammatory response syndrome (SIRS) 显示文摘 | Iwasaka H Noguchi T | 2004 | Nippon Rinsho2004，62，12： | 1 |
| 12 | Usefulness of plasma brain natriuretic peptide levels in predicting dobutamine induced myocardial ischemia 显示文摘 | Asada J Tsuji H Iwasaka T | 2004 | Am J Cardiol2004，93，6： | 1 |
| 13 | Adjuvant chemotherapy after radical hysterectomy for cervical carcinoma: A comparison with effects of adjuvant radiotherapy显示文摘 | Iwasaka T Kamura T Yokoyama M et al | 1998 | Obstet Gynecol1998，91，： | 1 |
| 14 | Th1/Th2 balance in systemic inflammatory response syndrome (SIRS) 显示文摘 | Iwasaka H Noguchi T | 2004 | Nippon Rinsho2004，62，12： | 1 |
| 15 | Endometrioid adenocarcinomas of the uterine corpus in women younger than 50 years of age Can be divided into two distinct clinical and pathologic entitles based on anatomic location显示文摘 | Hachisuga T Fukuda K Iwasaka T | 2001 | Cancer2001，92，10： | 1 |
| 16 | Recombinant throm-bomodulin prevents heatstroke by inhibition of high-mobilitygroup box 1 protein in sera of rats显示文摘 | Hagiwara S Iwasaka H Goto K | 2010 | Shock2010，34，4： | 1 |
| 17 | Comparative study of duplex-guided foam sclerotherapy and duplex-guided liquid sclerotherapy for the treatment of superficial venous insufficiency显示文摘 | Yamaki T Nozaki M Iwasaka S | 2004 | Dermatol Surg2004，30，5： | 1 |
| 18 | Usefulness of plasma brain natriuretie peptide levels in predicting dobutam ine-induced myo- cardial ischemial显示文摘 | Asada J Tsuji H Iwasaka T | 2004 | Am J Cardiol2004，93，6： | 1 |
| 19 | Gahexate mesilate inhibits the expression of HMGBI in lipopolysaccharide-induced acute lung injury显示文摘 | HIDAKA S IWASAKA H HAGIWARA S | 2011 | J Surg Res2011，165，1： | 1 |
| 20 | Usefulness of plasma brain natriuretic peptide levels in predicting dobutamine- induced myocardial ischemia 显示文摘 | Asada J Tsuji H Iwasaka T | 2006 | Am J Cardiol2006，93，6： | 1 |
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