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| 1 | Pancreaticopleuralfistula:etiology,treatmentandlong-termfollow-up显示文摘BACKGROUND:Pancreaticopleural fistula(PPF) are uncommon.Complex multidisciplinary treatment is required due to nutritional compromise and sepsis.This is the first description of long-term follow-up of patients with PPF.METHODS:Eleven patients with PPF treated at a specialist unit were identified.Causation,investigation,treatment and outcomes were recorded.RESULTS:Pancreatitis was the etiology of the PPF in 9 patients,and in the remaining 2 the PPF developed following distal pancreatectomy.Cross-sectional imaging demonstrated the site of duct disruption in 10 cases,with endoscopic retrograde cholangiopancreatography identifying the final case.Suppression of pancreatic exocrine secretion and percutaneous drainage formed the mainstay of treatment.Five cases resolved following pancreatic duct stent insertion and three patients required surgical treatment for established empyema.There were no complications.In all cases that resolved there has been no recurrence of PPF over a median follow-up of 50 months(range 15-62).CONCLUSIONS:PPF is an uncommon event complicating pancreatitis or pancreatectomy;pancreatic duct disruption is the common link.A step-up approach consisting of minimally invasive techniques treats the majority with surgery needed for refractory sepsis. | Keith J Roberts Maria Sheridan Gareth Morris-Stiff Andrew M Smith | 2012 | Hepatobiliary & Pancreatic Diseases International2012,11,2: | 2 |
| 2 | Coronary artery bypass graft surgery versus percutaneous coronary intervention in patients with three-vessel disease and left main coronary disease: 5-year follow-up of the randomised, clinical SYNTAX trial显示文摘 | Friedrich W Mohr Marie-Claude Morice A Pieter Kappetein Ted E Feldman Elisabeth St?hle Antonio Colombo Michael J Mack David R Holmes Marie-angèle Morel Nic Van Dyck Vicki M Houle Keith D Dawkins Patrick W Serruys | 2013 | The Lancet . 2013 (9867)2013,,9867: | 2 |
| 3 | Transepithelial leak in Barrett's esophagus patients: The role of proton pump inhibitors显示文摘AIM: To determine if the observed paracellular sucrose leak in Barrett's esophagus patients is due to their proton pump inhibitor (PPI) use. METHODS: The in vivo sucrose permeability test was administered to healthy controls, to Barrett's patients and to non-Barrett's patients on continuous PPI therapy. Degree of leak was tested for correlation with presence of Barrett's, use of PPIs, and length of Barrett's segment and duration of PPI use. RESULTS: Barrett's patients manifested a near 3-fold greater, upper gastrointestinal sucrose leak than healthy controls. A decrease of sucrose leak was observed in Barrett's patients who ceased PPI use for 7 d.Although initial introduction of PPI use (in a PPI-na ve population) results in dramatic increase in sucrose leak, long-term, continuous PPI use manifested a slow spontaneous decline in leak. The sucrose leak observed in Barrett's patients showed no correlation to the amount of Barrett's tissue present in the esophagus. CONCLUSION: Although future research is needed to determine the degree of paracellular leak in actual Barrett's mucosa, the relatively high degree of leak observed with in vivo sucrose permeability measurement of Barrett's patients reflects their PPI use and not their Barrett's tissue per se . | Christopher Farrell Melissa Morgan Owen Tully Kevin Wolov Keith Kearney Benjamin Ngo Giancarlo Mercogliano James J Thornton Mary Carmen Valenzano James M Mullin | 2012 | World Journal of Gastroenterology2012,18,22: | 2 |
| 4 | Isotopic composition and environment classification of selected limestone and fossils显示文摘 | Keith M H Weber J H | 1964 | Geochemical Cosmochimica Acta1964,28,: | 1 |
| 5 | Multiple pulmonary nodules in AIDS:usefulness of CT in distinguishing among potential causes显示文摘 | Keith J Edinburgh MD Robert M | 2000 | Radiology2000,214,2: | 1 |
| 6 | Predicting the ther mal conductivity of multiple carbon fillers in polypropylene- based resins 显示文摘 | Gaxiola D L Keith J M Mo Na | 2011 | J Compos Mater2011,45,12: | 1 |
| 7 | Carbon and oxygen isotopic composi tion of selected limestones and fossils显示文摘 | Keith M L Weber J N | 1964 | Geochimica et Cos- mochimica Acta1964,28,10: | 1 |
| 8 | A randomized, pharmacokinetic and pharmacodynamic, cross-over study of duodenal or jejunal administration compared to nasogastric administration of omeprazole suspension in patients at risk for stress ulcers显示文摘 | Jeffrey O Phillips Keith M Olsen Jill A Rebuck Nick J Rangnekar Brent W Miedema Michael H Metzler | 2001 | The American Journal of Gastroenterology2001,,: | 1 |
| 9 | Synthesis and biological activity of piperazine and diazepane amides that are histamine H3 antagonists and serotonin reuptake inhibitors显示文摘 | LY K S LETAVIC M A KEITH J M | 2008 | Bioorg Med Chem Lett2008,18,1: | 1 |
| 10 | Adverse effects of semen processing on human spem DNA integrity显示文摘 | Victor M Keith J Donna P | 1999 | J Urol1999,161,282: | 1 |
| 11 | Carbon and oxygen isotopic composition of selected limestone and fossils 显示文摘 | KEITH M L WEBER J N | 1964 | Geochim et Cosmochim Acta1964,28,10: | 1 |
| 12 | Climate strategy with CO2 capture from the air显示文摘 | Keith D W Duong M H Stolaroff J K | 2006 | Climatic Change2006,74,: | 1 |
| 13 | Evidence for a Second Crystal Form of Polypropylene显示文摘 | Keith H D Padden F J Walter N M | 1959 | J Appl Phys1959,30,10: | 1 |
| 14 | Isotopic composition and environmental classification of selected limestones and fossils显示文摘 | Keith M L Weber J N | 1964 | Geochimica et Cosmochimica Acta1964,28,: | 1 |
| 15 | Recent advances in discovery technologies显示文摘 | Keith J W Richard A M Michael W | 1997 | Neurotransmissions1997,5,3: | 1 |
| 16 | Performance of Finishing Pigs Fed Canola Meal in Growing and Finishing Diets显示文摘 | Bell J M Keith M O | 1988 | Nutr Rep Int1988,38,: | 1 |
| 17 | Carbon and Oxygen Isotopic Composition of Selected Limestones and Fossils显示文摘 | Keith M I Weber J N | 1964 | Geochimica et Cosmochimica Acta1964,28,: | 1 |
| 18 | Carbon and oxygen isotopic composition of selected limestones and fossils显示文摘 | Keith M L Weber J N | 1964 | Geochimica et Cosmochimica Acta1964,28,1011: | 1 |
| 19 | Nucleotide sequence of the structural glycoprotein VP7 gene of nebraska calf diarrhea virus rotavirus: comparison with homologous from four strain of human and animal rotavirus显示文摘 | Glass R I Keith J J Nakagomi O et M | 1985 | Virology1985,141,: | 1 |
| 20 | Regional Brain Iron, Ferritin and Transferrin Concentrations during Iron Deficiency and Iron Repletion in Developing Rats显示文摘 | Keith M Erikson Domingo J Pinero | 1997 | J Nutr1997,127,10: | 1 |