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	题名	作者	年代	出处	被引量
1	Differential reactivity of mouse monoclonal anti-HBs antibodies with recombinant mutant HBs antigens显示文摘AIM: To investigate the reactivity of a panel of 8 mouse anti-hepatitis B surface antigen (HBsAg) monoclonal antibodies (mAbs) using a collection of 9 recombinant HBsAg mutants with a variety of amino acid substitutions mostly located within the “a” region.METHODS: The entire HBs genes previously cloned into a mammalian expression vector were transiently transfected into COS7 cells. Two standard unmutated sequences of the ayw and adw subtypes served as controls. Secreted mutant proteins were collected and measured by three commercial diagnostic immunoassays to assess transfection efficiency. Reactivity of anti-HBs mAbs with mutated HBsAgs was determined by sandwich enzyme-linked immunosorbent assay (ELISA).RESULTS: Reactivity of anti-HBs mAbs with mutated HBsAgs revealed different patterns. While three mutants reacted strongly with all mAbs, two mutants reacted weakly with only two mAbs and the remaining proteins displayed variable degrees of reactivity towards different mAbs. Accordingly, four groups of mAbs with different but overlapping reactivity patterns could be envisaged. One group consisting of two mAbs (37C5-S7 and 35C6-S11) was found to recognize stable linear epitopes conserved in all mutants. Mutations outside the “a” determinant at positions 120 (P→S), 123(T→N) and 161(M→T) were found to affect reactivity of these mAbs.CONCLUSION: Our findings could have important implications for biophysical studies, vaccination strategies and immunotherapy of hepatitis B virus (HBV) mutants.	Azam Roohi Yaghoub Yazdani Jalal Khoshnoodi Seyed Mohammad Jazayeri William F Carman Mahmood Chamankhah Manley Rashedan Fazel Shokri	2006	World Journal of Gastroenterology2006，12，33：	4
2	Alpha-fetoprotein- producing gastric carcinoma with enteroblastic differen- tiation显示文摘	Matsunou H Konishi F Jalal RE	1994	Cancer1994，73，3：	1
3	GC-MS determination of PAHs in fish samples following salting-out-assisted solvent extractiongel permeation chromatography 显示文摘	Jalal H Abolfazl F	2011	Chromatographia2011，74，：	1
4	The undecimated wave- let decomposition and its reconstruction显示文摘	JEAN-LUC S JALAL F F1ONN M	2007	IEEE Transaction Image Processing2007，16，2：	1
5	Optimization of de-colorization of methylene blue by lignin peroxidase enzyme produced from sewage sludge with Phanerochaete chry-sosporium显示文摘	Alam M Z Mansor M F Jalal K C A	2009	Journal of Hazardous Materials2009，162，23：	1
6	Paraoxonase 3 activity and the ratio of antioxidant to peroxidation in the follicular fluid of infertile women显示文摘	Mohammad-Reza RR Jalal EK Laya F	2014	Int J Fertil Steril2014，，：	1
7	Carotid intima- media thickness and cardiovascular risk 显示文摘	Mookadam F Tanasunont W Jalal U	2011	Future Cardio2011，7，2：	1
8	Carotid intima - media thickness and cardiovascular risk 显示文摘	Mookadam F Tanasunont W Jalal U	2011	Future Cardio2011，7，2：	1
9	Alpha-protein producing gastric carcinoma with enteroblastic differentiation显示文摘	Matsunou H Konishi F Jalal REA	1994	Cancer1994，73，17：	1
10	Transient pressure behavior of Bingham non-Newtonian fluids for horizontal wells显示文摘	Jalal F O Djebbar T		0，，：	1
11	Carotid intimamedia thickness and cardiovascular risk显示文摘	Mookadam F Tanasunont W Jalal U	2011	Future Cardiol2011，7，2：	1
12	Structure of Anguibactin, a unique plasmid-related bacterial siderophore from the fish pathogen Vibrio anguillarum 显示文摘	Jalal M A F Hossain M B van der Helm D	1989	J Am Chem Soc1989，111，：	1
13	Measuring environmental performance in Asia 显示文摘	Jalal K F Rogers P P	2002	Ecological Indicators2002，2，：	1
14	Alpha-fetoprotein-producing gastric carcinoma with enteroblastic differentiation显示文摘	Matsunou H Konishi F Jalal RE	1994	Cancer1994，73，3：	1
15	Variation of stomata dimensions and densities in tolerant and susceptible wheat cultivars under drought stress显示文摘	Nastaran M Reza F Jalal S	2009	Journal of Food Agriculture & Environment2009，7，1：	1
16	Carotid intima-media thickness and cardiovascular risk显示文摘	Mookadam F Tanasunont W Jalal U		0，，02：	1
17	International agencies and the Asia-pacific environment 显示文摘	Jalal K F	1993	Environmental Science&Technology1993，27，12：	1
18	Optimization of decolorization of methylene blue by lignin peroxidase enzyme produced from sewage sludge with Phanerochaete chrysosporium显示文摘	Alama M Z Mansor M F Jalal K C A	2009	Journal of Hazardous Materials2009，162，：	1
19	Characterization of flow units in shaly sand reservoirs - Hassi R' mel Oil Rim, Algeria显示文摘	Redha C Aggoun Djebbar Tiab Jalal F Owayed	2006	Journal of Petroleum Science and Engineering2006，50，34：	1
20	Functionalstudies of a chimeric protein containing portions of theNa+/glucose and Na+/myoinositol cotransporters显示文摘	Coady MJ Jalal F Bissonnette P	2000	Biochim Biophy Acta2000，1466，：	1

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