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| 1 | 黄芪总黄酮对扑热息痛所致肝损伤的防护机理探讨显示文摘目的 :研究黄芪总黄酮对扑热息痛所致肝损伤的防护机理。方法 :用高压液相测定扑热息痛及代谢产物和苯巴比妥诱导睡眠模型研究黄芪总黄酮 (TFA)对扑热息痛的代谢及TFA抗扑热息痛所致损伤的机理。结果 :TFA可明显降低尿中硫醚胺酸的浓度 ,其变化与TFA浓度成反比 ;但对其它代谢产物的影响无明显统计学差异。苯巴比妥诱导小鼠睡眠实验结果显示 ,TFA (10 0mg·kg-1)本身对苯巴比妥代谢无明显影响 (P >0 .0 5 ) ,扑热息痛 (40 0mg·kg-1)可显著延长小鼠的睡眠时间 (P <0 .0 0 1) ;但TFA (10 0mg·kg-1)明显缩短扑热息痛所延长的苯巴比妥诱导的睡眠时间 (P <0 .0 0 5 )。结论 | 汪德清 Critchley Julian AJH 丁保国 马艳青 赵海潞 Thomas G Neil 田亚平 Tomlinson B rian Critchley Lester AH James Anthony Edward | 2001 | 中国中药杂志2001，26，9： | 13 |
| 2 | Gastric intestinal metaplasia is associated with gastric dysplasia but is inversely correlated with esophageal dysplasia显示文摘AIM To determine which clinical factors might be associated with gastric intestinal metaplasia(IM) in a North American population.METHODS Pathology and endoscopy databases at an academicmedical center were reviewed to identify patients with and without gastric IM on biopsies for a retrospective cohort study. Patient demographics, insurance status, and other clinical factors were reviewed.RESULTS Four hundred and sixty-eight patients with gastric IM(mean age: 61.0 years ± 14.4 years, 55.5% female) and 171 without gastric IM(mean age: 48.8 years ± 20.8 years, 55.0% female) were compared. The endoscopic appearance of atrophic gastritis correlated with finding gastric IM on histopathology(OR = 2.05, P = 0.051). Gastric IM was associated with histologic findings of chronic gastritis(OR = 2.56, P < 0.001), gastric ulcer(OR = 6.97, P = 0.015), gastric dysplasia(OR = 6.11, P = 0.038), and gastric cancer(OR = 6.53, P = 0.027). Histologic findings of Barrett's esophagus(OR = 0.28, P = 0.003) and esophageal dysplasia(OR = 0.11, P = 0.014) were inversely associated with gastric IM. Tobacco use(OR = 1.73, P = 0.005) was associated with gastric IM.CONCLUSION Patients who smoke or have the endoscopic finding of atrophic gastritis are more likely to have gastric IM and should have screening gastric biopsies during esophagogastroduodenoscopy(EGD). Patients with gastric IM are at increased risk for having gastric dysplasia and cancer, and surveillance EGD with gastric biopsies in these patients might be reasonable. | Justin M Gomez James T Patrie Wissam Bleibel Jeanetta W Frye Bryan G Sauer Vanessa M Shami Edward B Stelow Christopher A Moskaluk Andrew Y Wang | 2017 | World Journal of Gastrointestinal Endoscopy2017，9，2： | 3 |
| 3 | DNA damage induced by chronic inflammation contributes to colon carcinogenesis in mice显示文摘 | Meira Lisiane B Bugni James M Green Stephanie L Lee Chung-Wei Pang Bo Borenshtein Diana Rickman Barry H Rogers Arlin B Moroski-Erkul Catherine A McFaline Jose L Schauer David B Dedon Peter C Fox James G Samson Leona D | 2008 | Journal of Clinical Investigation2008，，7： | 2 |
| 4 | Security Models for Web-based Applications 显示文摘 | James B D Joshi Walid G Aref | 2001 | Communications of the ACM2001，44，2： | 2 |
| 5 | Determining the fluxes of Tl^+ and K^+ at the root surface of wheat and canola using Tl( I ) and K ion-selective microelectrodes显示文摘 | JAMES G H MICHAEL J O EDWARD B | 2010 | Plant Soil2010，335，1： | 1 |
| 6 | Alliances: The new strategic focus 显示文摘 | James B G | 1985 | Long Range Planning1985，18，3： | 1 |
| 7 | Welcome to the experience economy显示文摘 | James G H | 1998 | Harvard Business Review1998，35，7： | 1 |
| 8 | Genome, transcriptome, and secretome analysis of wood decay fungus Postia placenta supports unique mechanisms of lignocellulose conversion 显示文摘 | Martinez D Challacombe J Morgenstern 1 Hibbett D Schmoll M Kubicek CP Ferreira P Ruiz-Duenas FJ Martinez AT Kersten P Hammel KE Wymelenberg AV Gaskell J Lindquist E Sabat G BonDurant SS Larrondo LF Canessa P Vicuna R Yadav J Doddapaneni H Subramanian V Pisabarro AG Lavin JL Oguiza JA Master E Henrissat B Coutinho PM Harris P Magnuson JK Baker SE Bruno K Kenealy W Hoegger PJ Kties U Ramaiya P kucas S Salamov A Shapiro H Tu H Chee CL Misra M Xie G Teter S Yaver D James T Mokrejs M Pospisek M Grigoriev IV Brettin T Rokhsar D Berka R Cullen D | 2009 | PNAS2009，106，6： | 1 |
| 9 | Effect of down- regulation of ethylene biosynthesis on fruit flavor complex in apple fruit显示文摘 | DANDEKAR A M TEO G DEFILIPPI B G URATSU S L PASSEY A J KADER A A STOW J R COLGAN R J JAMES D J | 2004 | Transgenic Research2004，13，： | 1 |
| 10 | The electrical and thermal conductivity of woven pristine and intercalated graphite fiberpolymer composites显示文摘 | James R G Yvonne Y V Steven B | 2003 | Carbon2003，41，12： | 1 |
| 11 | Influence of the cooling scheme on the performance and presence of carrier traps for CdMnTe detectors 显示文摘 | KIM K H JENG G KIM P CHOI J BOLOTNIKOV A E CAMARDA G S JAMES R B | 2013 | Journal of Applied Physics2013，114，06： | 1 |
| 12 | Real-time 3-D ultrasound imaging using sparse synthetic aperture beamforming显示文摘 | Lockwood G R James R T Shelby S B | 1998 | IEEE Trans Ultrason Ferroelec Freq Contr1998，45，4： | 1 |
| 13 | Influence of fiber length on the mechanical properties of wood-fiber/polypropylene prepreg sheets 显示文摘 | Lee B J McDonald A G James B | 2001 | Materials Research Innovations2001，4，23： | 1 |
| 14 | Recent advance in techniques for hyperspectral image processing显示文摘 | Antonio P Jon A B Joseph W B Jason B Lorenzo B Gustavo C V Jocelyn C Mathieu F Paolo G Anthony G Mattia M James C T Giovanna T | 2009 | Remote Sensing of Environment2009，113，： | 1 |
| 15 | Synthesis and properties of fatty imidazolines and their N-(2-aminoethyl) derivatives显示文摘 | Raymond G B J R James W H | 1983 | Journal of the American ChemicalSociety1983，80，4： | 1 |
| 16 | Vanadium-doped cadmium manganese telluride (Cdl~MnxTe) crystals as X-and gamma-ray detectors 显示文摘 | HOSSAIN A CUI Y BOLOTNIKOV A E CAMARDA G S YANG G KOCHANOWSKA D JAMES R B | 2009 | Journal of Electronic Materials2009，38，8： | 1 |
| 17 | Determination of postmortem interval by sampling vitreous humour显示文摘 | James R A Hoadley P A Sampson B G | 1997 | Am J Forensic Med Pathol1997，18，2： | 1 |
| 18 | Molecular models of brown coal containing inorganic species显示文摘 | DOMAZETIS G JAMES B | 2006 | Org Geochem2006，37，2： | 1 |
| 19 | The advanced multifunction RF concept显示文摘 | Tavik G C Hilterbrick Charles L Evins James B | 2005 | IEEE MTT2005，53，3： | 1 |
| 20 | Improved sense-amplifier-based flip-flop:Design and measurements显示文摘 | NIKOLIC B OKLOBDZIJA V G STOJANOVIC V JIA W Y JAMES K C MING-TAK L M | 2000 | IEEE Journal of Solid-State Circuits2000，35，6： | 1 |
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