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| 1 | Role of PRMTs in cancer: Could minor isoforms be leaving a mark?显示文摘Protein arginine methyltransferases(PRMTs) catalyze the methylation of a variety of protein substrates, many of which have been linked to the development, progression and aggressiveness of different types of cancer. Moreover, aberrant expression of PRMTs has been observed in several cancer types. While the link between PRMTs and cancer is a relatively new area of interest, the functional implications documented thus far warrant further investigations into its therapeutic potential. However, the expression of these enzymes and the regulation of their activity in cancer are still significantly understudied. Currently there are nine main members of the PRMT family. Further, the existence of alternatively spliced isoforms for several of these family members provides an additional layer of complexity. Specifically, PRMT1, PRMT2, CARM1 and PRMT7 have been shown to have alternative isoforms and others may be currently unrealized. Our knowledge with respect to the relative expression and the specific functions of these isoforms is largely lacking and needs attention. Here we present a review of the current knowledge of theknown alternative PRMT isoforms and provide a rationale for how they may impact on cancer and represent potentially useful targets for the development of novel therapeutic strategies. | R Mitchell Baldwin Alan Morettin Jocelyn C té | 2014 | World Journal of Biological Chemistry2014，5，2： | 14 |
| 2 | Application of the microwave-assisted process to the fast extraction of ginseng saponins显示文摘 | Joong-Ho Kwon Jacqueline M R Belanger J R Jocelyn Pare | 2003 | Food Research International2003，，36： | 1 |
| 3 | Zinc intake of the U S population: findings from the third national health and nutrition examination survey 1988~1994 显示文摘 | Briefel R R Bialostosky K Jocelyn K S | 2000 | J Nutr2000，130，： | 1 |
| 4 | Salmonella carrier-state in hens: study of host resistance by a gene expression approach显示文摘 | Jean-Rémy Sadeyen Jér?me Trotereau Jocelyne Protais Catherine Beaumont Nadine Sellier Gilles Salvat Philippe Velge Anne-Christine Lalmanach | 2006 | Microbes and Infection2006，，5： | 1 |
| 5 | Information seeking and anxiety among colonoscopy-na?ve adults: direct-to-colonoscopy vs traditional consult-first pathways显示文摘AIM To investigate the effects of direct to colonoscopy pathways on information seeking behaviors and anxiety among colonoscopy-na?ve patients.METHODS Colonoscopy-na?ve patients at two tertiary care hospitals completed a survey immediately prior to their scheduled outpatient procedure and before receiving sedation.Survey items included clinical pathway(direct or consult),procedure indication(cancer screening or symptom investigation),telephone and written contact from the physician endoscopist office,information sources,and pre-procedure anxiety.Participants reported pre-procedure anxiety using a 10 point scale anchored by 'very relaxed'(1) and 'very nervous'(10).At least three months following the procedure,patient medical records were reviewed to determine sedative dose,procedure indications and any adverse events.The primary comparison was between the direct and consult pathways.Given the very different implications,a secondary analysis considering the patient-reported indication for the procedure(symptoms or screening).Effects of pathway(direct vs consult) were compared both within and between the screening and symptom subgroups.RESULTS Of 409 patients who completed the survey,34% followed a direct pathway.Indications for colonoscopy were similar in each group.The majority of the participants were women(58%),married(61%),and internet users(81%).The most important information source was family physicians(Direct) and specialist physicians(Consult).Use of other information sources,including the internet(20% vs 18%) and Direct family and friends(64% vs 53%),was similar in the Direct and Consult groups,respectively.Only 31% of the 81% who were internet users accessed internet health information.Most sought fundamental information such as what a colonoscopy is or why it is done.Pre-procedure anxiety did not differ between care pathways.Those undergoing colonoscopy for symptoms reported greater anxiety [mean 5.3,95%CI: 5.0-5.7(10 point Likert scale)] than those for screening colonoscopy(4.3,95%CI: 3.9-4.7).CONCLUSION Procedure indication(cancer screening or symptom investigation) was more closely associated with information seeking behaviors and pre-procedure anxiety than care pathway. | Jocelyn A Silvester Harmandeep Kalkat Lesley A Graff John R Walker Harminder Singh Donald R Duerksen | 2016 | World Journal of Gastrointestinal Endoscopy2016，8，19： | 1 |
| 6 | Application of microwave- assisted process to the fast extraction of ginseng saponins显示文摘 | Kwon J H Belanger J M R Jocelyn Pare J R | 2003 | Food research international2003，36，5： | 1 |
| 7 | ESTs, cDNA microarray, and gene expression profiling : tools for dissecting plant physiology and development显示文摘 | AIBA R FEI Z J PAYTON P LIU Y MOORE S L DEBBIE P COHN J D'ASCENZO M GORDON J S JOCELYN K C ROSE MARTIN G TANKSLEY S D BOUZAYEN M JAHN M M GIOVANNONI J | 2004 | Plant Journal2004，39，5： | 1 |
| 8 | Microwave- Assisted Process (MAP):a new tool for the analytical laboratory显示文摘 | JOCELYN P J R JACQUELINE M R B SALLY S S | 1994 | Trends in Analytical Chemistry1994，13，4： | 1 |
| 9 | High pressure thawing of fish and shellfish显示文摘 | JOCELYN R ALAIN L RAMASWAMYB H S | 2002 | Journal of Food Engineering2002，53，1： | 1 |
| 10 | Amino acids interfere with the ninhydrin assay for asparagines显示文摘 | Paul L H Ben K S Jocelyn R E | 1995 | Food Chemistry1995，53，： | 1 |
| 11 | A critical evaluation of sample extraction techniques for enhanced proteomic analysis of recalcitrant plant tissues 显示文摘 | Ramu S Saravanan Jocelyn K C R | 2004 | Proteomics2004，，4： | 1 |
| 12 | Amino acids interfere with the ninhydrin assay for asparagines显示文摘 | Paul L H Ben K S Jocelyn R E | 1995 | Food Chemistry1995，53，： | 1 |
| 13 | Application of the microwave-assisted process (mapTM) to the fast extraction of ginseng saponins显示文摘 | Joong-Ho Kwon Jacqueline M R B61anger J R Jocelyn Par6 | 2003 | Food Research international2003，36，5： | 1 |
| 14 | Isolation and characterization of Urbain, a 20-hydroxyecdysone-inducible gene expressed during morphogenesis of Bombyx mori wing imaginal discs显示文摘 | Marie Thérèse Besson Pascal Chareyre Gilbert Deléage Jocelyne Demont Brigitte Quennedey Annie Courrent Jacques Fourche Georges Bosquet | 1996 | Roux’s Archives of Developmental Biology (-)1996，，7： | 1 |
| 15 | Structural heterogeneities and mechanical properties of vinyl/dimethaerylate networks synthesized by thermal free radical polymerisation 显示文摘 | LAURENT R JANNICK D JOCELYNE G | 2002 | Polymer2002，43，： | 1 |
| 16 | Zinc intake of the US population:findings from the third national healt h and nut rition exam ination survey 1988~1994显示文摘 | Briefel R R Bialostosky K Jocelyn K S | 2000 | J Nutr2000，，： | 1 |
| 17 | Corn as a production system for human and animal vaccines显示文摘 | Stephen J Streatfield Jeffrey R Lane Christopher A Brooks Donna K Barker Miranda L Poage Jocelyne M Mayor Barry J Lamphear Carol F Drees Joseph M Jilka Elizabeth E Hood John A Howard | 2002 | Vaccine2002，，7： | 1 |
| 18 | A critical evaluation of sample extraction techniques for enhanced proteomic analysis of recalcitrant plant tissues显示文摘 | SARAVANAN R S JOCELYN K | 2004 | Proteomics2004，4，9： | 1 |
| 19 | Mucosal damage in the esophageal remnant after esophagectomy and gastric transposition显示文摘 | Xavier Benoit DJ Jocelyne M Georges R | 2009 | Ann Surg2009，249，2： | 1 |
| 20 | Prognostic Factors for Outcome in Patients With Aneurysmal Subarachnoid Hemorrhage显示文摘 | Axel J. Rosengart Kim E. Schultheiss Jocelyn Tolentino R Loch Macdonald | 2007 | Stroke2007，，8： | 1 |
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