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| 1 | Potentiation of NETs release is novel characteristic of TREM-1 activation and the pharmacological inhibition of TREM-1 could prevent from the deleterious consequences of NETs release in sepsis显示文摘During sepsis,neutrophil activation induces endothelial cell(EC)dysfunction partly through neutrophil extracellular trap(NET)release.The triggering receptor expressed on myeloid cell-1(TREM-1)is an orphan immune receptor that amplifies the inflammatory response mediated by Toll-like receptor-4(TLR4)engagement.Although the key role of TLR4 signaling in NETosis is known,the role of TREM-1 in this process has not yet been investigated.Here,we report that TREM-1 potentiates NET release by human and murine neutrophils and is a component of the NET structure.In contrast,pharmacologic inhibition or genetic ablation of TREM-1 decreased NETosis in vitro and during experimental septic shock in vivo.Moreover,isolated NETs were able to activate ECs and impair vascular reactivity,and these deleterious effects were dampened by TREM-1 inhibition.TREM-1 may,therefore,constitute a new therapeutic target to prevent NETosis and associated endothelial dysfunction. | Amir Boufenzer Kevin Carrasco Lucie Jolly Benjamin Brustolin Elisa Di-Pillo Marc Derive Sébastien Gibot | 2021 | Cellular & Molecular Immunology2021，18，2： | 9 |
| 2 | Comparison of effectiveness of enoxaparin versus unfractionated heparin to reduce silent and Clinical- ly apparent acute myocardial infarction in patients presenting with non -ST- segment elevation acute coronary syndrome 显示文摘 | Jolly S Tan M Mendelsohn A | 2007 | Am J Cardiol2007，99，2： | 1 |
| 3 | Submitochondrial distribution and delayed proteolysis of subunit c of the H+-transporting ATP-synthase in ovine cer- oid-lipofuscinosis显示文摘 | H-UGHES S M MORONI-RAWSON P JOLLY R D | 2001 | Electrophoresis2001，22，9： | 1 |
| 4 | Low-dose vsstandard-dose un-fractionated heparin for percutaneous coro-nary intervention in acute coronary syndromes treated withfondaparinux:the FUTURA/OASIS-8randomized trial显示文摘 | STEG P G JOLLY S S MEHTA S R | 2010 | JAMA2010，304，12： | 1 |
| 5 | Evaluating agricultural nonpoint-source pollution using integrated geographic information systems and hydrologic/water quality model显示文摘 | Tim U S R Jolly | 1994 | J Environ Qual1994，23，1： | 1 |
| 6 | Radial versus femoral access for coronary angiography and intervention in patients with acute coronary syndromes(RIVAL):a randomised,parallel group,multicentre trial显示文摘 | Jolly SS Yusuf S Cairns J | 2011 | Lancet2011，377，9775： | 1 |
| 7 | De-sign and rationale of the radial versus femoral accessfor coronary intervention (RIVAL) trial: a random-ized comparison of radial versus femoral access forcoronary angiography or intervention in patients withacute coronary syndromes 显示文摘 | JOLLY S S NIEMELA K XAVIER D | 2011 | Am Heart J2011，161，： | 1 |
| 8 | B-type natriuretic peptide and serum unbound free fatty acid levels after contemporary percutaneous coronary intervention显示文摘 | Cantor WJ Kim HH Jolly S | | 0，，： | 1 |
| 9 | Reaction mechanisms and kinetics in the n-hexane cracking over zeolites 显示文摘 | Jolly S Saussey J Bettahar M M | 1997 | Applied Catalysis A: General1997，156，： | 1 |
| 10 | Radial versus femoral access for coronary angiography or intervention and the impact on major bleeding and ischemic events:a systematic review and meta-analysis of randomized trials显示文摘 | Jolly SS Amlani S Hamon M | 2009 | Am Heart J2009，157，1： | 1 |
| 11 | Reaction mechanisms and kinetics in the n-hexane cracking over zeolites显示文摘 | JOLLY S SAUSSEY J BETTAHAR M M LAVALLEY J C BENAZZI E | 1997 | Appl Catal A:Gen1997，156，1： | 1 |
| 12 | Radial versus femoral access for cor-onary angiography and intervention in patients with acute coronary syn-dromes (RIVAL) ; a randomized, parallel group, multicenter trail显示文摘 | Jolly SS Yusuf S Caims J | 2011 | Lancet2011，377，： | 1 |
| 13 | Radial versus femoral ac- cess for coronary, angiography or intervention and the impact on major bleeding and ischemic events: a systematic review and me'la-analysis of randomized trials显示文摘 | Jolly SS Amlani S Hamon M | 2009 | Am Heart J2009，157，1： | 1 |
| 14 | An evaluateon of Phaffia yeast as a pigment source for salmonids显示文摘 | Binkowski F P Sedmak J J Jolly S O | 1993 | Aquacul Mag1993，19，： | 1 |
| 15 | Perils of rib fractures 显示文摘 | Sharma OP Oswanski MF Jolly S | 2008 | Am Surg2008，74，4： | 1 |
| 16 | Radial versus femoral access for coronary angi-ography and intervention in patients with acute coronarysyndromes(RIVAL):a randomised,parallel group,multicentre trial显示文摘 | Jolly S S | 2011 | Lancet2011，377，9775： | 1 |
| 17 | Radial versus femoral access for coronary angiography and intervention in patients with acute coronary syndromes (RIVAL): a randomised, parallel group, multicentre trial 显示文摘 | Jolly SS Yusuf S Cairns J | 2011 | Lancet2011，377，9775： | 1 |
| 18 | The role and use of non-saccharomyees yeasts in wine production显示文摘 | Jolly N Augustyn O Pretorius S | 2006 | South African Journal for Enology and Viticulture2006，27，1： | 1 |
| 19 | Dose comparisons of clopidogrel and aspirin in acute coronary syndromes显示文摘 | Fox KA Granger CB Jolly S | 2010 | N Engl J Med2010，363，： | 1 |
| 20 | Perils of rib frac- tures显示文摘 | Sharma OP Oswanski MF Jolly S | 2008 | Am Surg2008，74，4： | 1 |
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