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| 1 | 复合材料薄板在低速冲击下的破坏分析:试验和数值方法显示文摘在冲击荷载作用下,复合层压板破坏过程中有很多并发现象,因此,复合层压板的动力性能十分复杂。当采用复合材料结构时,对于接触和较大的位移导致的纤维破坏、分层、模具破裂、塑性变形应给予重视。对碳纤维环氧树脂加固的层压复合薄板进行低速冲击下的研究。采用荷载时间序列、位移时间序列、能量时间序列以及来自NDE的图像,分析叠加系列和能量响应的影响。当层压复合薄板受到低速外来目标的冲击时,由压痕试验结果与动力学的结果比较,验证了迟滞效应。采用希尔模型和ABAQUS软件中由UMAT补充的材料模型,通过有限元分析以模拟压痕试验的破坏机制。 | Volnei Tita Jonas de Carvalho Dirk Vandepitte | 2008 | 钢结构2008，23，9： | 12 |
| 2 | Discriminating mild from critical COVID-19 by innate and adaptive immune single-cell profiling of bronchoalveolar lavages显示文摘How the innate and adaptive host immune system miscommunicate to worsen COVID-19 immunopathology has not been fully elucidated.Here,we perform single-cell deep-immune profiling of bronchoalveolar lavage(BAL)samples from 5 patients with mild and 26 with critical COVID-19 in comparison to BALs from non-COVID-19 pneumonia and normal lung.We use pseudotime inference to build T-cell and monocyte-to-macrophage trajectories and model gene expression changes along them.In mild COVID-19,CD8^(+)resident-memory(TRM)and CD4^(+)T-helper-17(T_(H17))cells undergo active(presumably antigen-driven)expansion towards the end of the trajectory,and are characterized by good effector functions,while in critical COVID-19 they remain more naïve.Vice versa,CD4^(+)T-cells with T-helper-1 characteristics(TH1-like)and CD8^(+)T-cells expressing exhaustion markers(T_(EX)-like)are enriched halfway their trajectories in mild COVID-19,where they also exhibit good effector functions,while in critical COVID-19 they show evidence of inflammation-associated stress at the end of their trajectories.Monocyte-to-macrophage trajectories show that chronic hyperinflammatory monocytes are enriched in critical COVID-19,while alveolar macrophages,otherwise characterized by anti-inflammatory and antigen-presenting characteristics,are depleted.In critical COVID-19,monocytes contribute to an ATP-purinergic signaling-inflammasome footprint that could enable COVID-19 associated fibrosis and worsen disease-severity.Finally,viral RNA-tracking reveals infected lung epithelial cells,and a significant proportion of neutrophils and macrophages that are involved in viral clearance. | Els Wauters Pierre Van Mol Abhishek Dinkarnath Garg Sander Jansen Yannick Van Herck Lore Vanderbeke Ayse Bassez Bram Boeckx Bert Malengier-Devlies Anna Timmerman Thomas Van Brussel Tina Van Buyten Rogier Schepers Elisabeth Heylen Dieter Dauwe Christophe Dooms Jan Gunst Greet Hermans Philippe Meersseman Dries Testelmans Jonas Yserbyt Sabine Tejpar Walter De Wever Patrick Matthys CONTAGIOUS collaborators Johan Neyts Joost Wauters Junbin Qian Diether Lambrechts | 2021 | Cell Research2021，31，3： | 11 |
| 3 | Glucoseresponsive polyelectrolyte capsules 显示文摘 | DE GEEST BG JONAS AM DEMEESTER J | 2006 | Langmuir2006，22，11： | 1 |
| 4 | Drying methods forprotein pharmaceuticals显示文摘 | Maltesen Morten Jonas Van de Weert Marco | 2008 | Drug Discovery Today:Technologies2008，5，23： | 1 |
| 5 | Systematic review:comparative effectiveness and harms of disease-modifying medications for rheumatoid arthritis显示文摘 | DONAHUE KE GARTLEHNER G JONAS DE | 2008 | Ann Intern Med2008，148，2： | 1 |
| 6 | Systematic review:comparative effectiveness and har ms of disease-modifying medications for rheumatoid arthritis显示文摘 | Donahue KE Gatehner G Jonas DE | 2008 | Ann InternMed2008，148，2： | 1 |
| 7 | Failure analysis of low velocity impact on thin composite laminates: Experimental and numerical approaches显示文摘 | Volnei Tita Jonas de Carvalho Dirk Vandepitte | 2007 | Composite Structures2007，，4： | 1 |
| 8 | Rapid Decrease in Delivery of Chemotherapy to Tumors after Anti-VEGF Therapy: Implications for Scheduling of Anti-Angiogenic Drugs显示文摘 | Astrid A.M. Van der Veldt Mark Lubberink Idris Bahce Maudy Walraven Michiel P. de Boer Henri N.J.M. Greuter N. Harry Hendrikse Jonas Eriksson Albert D. Windhorst Pieter E. Postmus Henk M. Verheul Erik H. Serné Adriaan A. Lammertsma Egbert F. Smit | 2012 | Cancer Cell2012，，： | 1 |
| 9 | Pharmacogenomic testing and the prospect of individualized treatment显示文摘 | Jonas DE Wines R | | 0，，06： | 1 |
| 10 | Genetic and clinical factors relating to warfarin dosing显示文摘 | Jonas DE Mcleod HL | 2009 | Trends in Pharmacological Sciences2009，30，7： | 1 |
| 11 | Layer-by-layer coating of degradable microgels for pulsed drug delivery显示文摘 | De Geest B G D jugnat C Verhoeven E Sukhorukov G B Jonas A M Plain J | 2006 | J Contr Rel2006，116，： | 1 |
| 12 | Self exploding lipid-coated microgels显示文摘 | De Geest B G Stubbe B G Jonas A M Van Thienen T Hin richs W L J Demeester J | 2006 | Biomacromolecules2006，7，： | 1 |
| 13 | Genetic and clinical factors relating to warfarin dosing显示文摘 | Jonas DE Mcleod HL | 2009 | Trends Pharmacol Sci2009，30，： | 1 |
| 14 | Genetic and clinical factors relating to warfarin dosing显示文摘 | Jonas DE Mc-Leod HL | 2009 | Trends Pharmacol Sci2009，30，7： | 1 |
| 15 | Impaet of genotype-guid- ed dosing on anticoagulation visits for adults starting warfarin: a ran- domized controlled trial 显示文摘 | Jonas DE Evans JP McLeod HL | 2013 | Pharmacogenomics2013，14，13： | 1 |
| 16 | Pharmacogenomic testing and the prospeet of individualized treatment 显示文摘 | Jonas DE Wines R | 2013 | N C Med J2013，74，6： | 1 |
| 17 | Deconstructing the placebo effect and finding the meaning response显示文摘 | Moerman DE Jonas WB | 2002 | Ann Intern Med2002，，6： | 1 |
| 18 | Systematic review:comparativeefectiveness and harms of disease-modifying medications for rheumatoid arthritis显示文摘 | Donahue KE Gartlehner G Jonas DE | 2008 | Ann Intern Med2008，148，2： | 1 |
| 19 | Glucoseresponsive polyelectrolyte capsules显示文摘 | De Geest B G Jonas A M Demeester J | 2006 | Langmuir2006，22，11： | 1 |
| 20 | Everolimus With Reduced Tacrolimus Improves Renal Function in De Novo Liver Transplant Recipients: A Randomized Controlled Trial显示文摘 | P. De Simone F. Nevens L. De Carlis H. J. Metselaar S. Beckebaum F. Saliba S. Jonas D. Sudan J. Fung L. Fischer C. Duvoux K. D. Chavin B. Koneru M. A. Huang W. C. Chapman D. Foltys S. Witte H. Jiang J. M. Hexham G. Junge | 2012 | American Journal of Transplantation2012，，11： | 1 |
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