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    题名 作者 年代 出处 被引量
1CTNNB1/β-catenin:涎腺基底细胞肿瘤鉴别标志物显示文摘由于涎腺基底细胞腺瘤和腺癌在形态学方面表现相似,其主要区别在于肿瘤是否浸润生长至涎腺实质和(或)涎腺外组织,因而涎腺基底细胞肿瘤的鉴别诊断存在挑战,尤其对于穿刺活检标本。CTNNBl基因位于染色体3p21,β-cate.nin是其编码产物蛋白。J0等检测73例涎腺肿瘤(22例基底细胞腺瘤、3例基底细胞腺癌、20例多形性腺瘤、20例腺样囊性癌及8例上皮-肌上皮癌)中β-catenin的表达以及6例涎腺基底细胞肿瘤(5例基底细胞腺瘤、1例基底细胞腺癌)中CTNNB1突变状况。Jo V Y Sholl L M Krane J F 杨海玉 刘勇 2016临床与实验病理学杂志2016,32,11:7
2A regionalized IO-model to value seasonal recreational ecosystem services in a mountain National Park in Spain显示文摘Recreational Ecosystem Services(RES)are among the most frequently evaluated ecosystem services.RES are seen as a major opportunity for sustainable development in areas of high ecological value resulting from the presence of emblematic species,habitats or scenery,often integrated in conservation areas,in particular in mountain areas affected by depopulation,rising environmental risks and poverty.Economically,the assessment of RES has been based on Contingent Valuation and Choice Experiments,methods with limitations related to their subjectivity.Alternatively,Input-Output(IO)models provide a very accurate and effective way of valuation of RES with regional information regarding interindustry transactions.Whilst data on nature tourist expenditure may be only available annually,tourism inflows have a strong seasonal behavior,which impacts the profitability of several local economic activities.In this paper,we firstly constructed a novel regionalized IO-model based on Cross-Industry Location Quotients using employment data and,secondly,based on Monte Carlo simulation,we estimated nature tourist expenditure monthly using data on nature tourism inflows.This method allowed for a more precise RES evaluation,estimating direct,indirect and induced monthly economic impacts of nature-based tourism.The method was applied to the Ordesa and Monte Perdido(OMP)National Park in the Spanish Pyrenees.To estimate the average tourist expenditure,we collected and analyzed spending on commerce,hospitality and restaurants,leisure,and transport of 385 visitors.Results suggest that using a regionalized IO model leads to a considerable reduction of over-estimation of the economic impact of tourist expenditure estimated by conventional methods.Taking into consideration the direct,indirect and induced effects of tourist expenditure in 2016-2018,the total annual output effect in the OMP National Park amounted to€208.8 million,while the total income effect amounted to€86.29 million.Also,a total of 2,429 jobs were created which indicates that for each thousand annual visitors to the National Park,3.8 jobs are created in the surrounding area.Overall,the proposed methodology can be easily applied to the remaining National Parks in Spain or other regions in the world,making it a valuable tool to estimate the value of RES in areas affects by strong seasonality,to set priorities and support regional policies for mountain sustainable development.Víctor MARTIN BARROSO Mónica de CASTRO-PARDO Pascual FERNÁNDEZ MARTÍNEZ João C.AZEVEDO 2022Journal of Mountain Science2022,19,1:2
3uPAR induces epi-thelial-mesenchymal transition in hypoxic breast cancer cells显示文摘Lester RD Jo M Montel V Takimoto S 2007J Cell Biol2007,178,3:1
4uPAR induces epithelial mesenchymal transition in hypoxic breast cancer cells显示文摘LESTER R D JO M MONTEL V 2007Cell Biol2007,178,3:1
5Comparative and demographic analysis of orangutan genomes显示文摘Locke DP Hillier LW Warren WC Worley KC Nazareth LV Muzny DM Yang SP Wang Z Chinwalla AT Minx P Mitreva M Cook L Delehaunty KD Fronick C Schmidt H Fulton LA Fulton RS Nelson JO Magrini V Pohl C Graves TA Markovic C Cree A Dinh HH Hume J Kovar CL Fowler GR 0,,:1
6Resistance of different fungal structures of Duddingtonia flagrans to the digestive process and predatory ability on larvae of Haemonchus contortus and Strongyloides papillo sus in goat feces显示文摘Artur K Campos J V Araújo M P 0,,:1
7一种新认识的酷似涎腺基底样癌的成釉细胞瘤样尤文肉瘤显示文摘骨外成釉细胞瘤样尤文肉瘤(ALES)是一种罕见肿瘤,除了具有明显的上皮样分化,包括弥漫表达CK和p40外,还显示特征性的EWSR1-FLI1基因易位。迄今为止所报道的ALES多见于头颈部,可酷似小蓝圆细胞肿瘤。由于ALES在形态学上很难与涎腺的基底细胞样癌鉴别,为此,作者选取10例发生在涎腺的ALES进行研究,旨在提高对该肿瘤特征的认识。Rooper L M Jo V Y Antonescu C R 王婷 余英豪 2019临床与实验病理学杂志2019,35,3:1
8Plant sterols:Friend or foe in CNS disorders? 显示文摘Tim V Jeroen F J Jo M 2015Progress Lipid Research2015,58,:1
9uPAR induces epithelial-mesenchymal transition in hypoxic breast cancer cells显示文摘Lester RD Jo M Montel V 2007J Cell Biol2007,178,3:1
10uPAR induces epithelial-rues enehymal transition in hypoxic breast cancer ceils 显示文摘Lester RD Jo M Montel V 2007J Cell Bi- ol2007,178,3:1
11uPAR induces epi- thelial-mesenchymal transition in hypoxic breast cancer cells 显示文摘LESTER R D JO M MONTEL V 2007JCellBiol2007,178,3:1
12Malignancy risk for fine-needle aspiration of thyroid lesions according to the Bethesda System for Reporting Thyroid Cytopathology显示文摘Jo V Y Stelow E B Dustin S M 0,,24:1
13Synthetic lethali-ty between eIF5A and Ypt1 reveals a connection between translation andthe secretory pathway in yeast显示文摘FRIGIERI M C JOO LUIZ M V S APPONI L H 2008Mol Genet Genomics2008,280,:1
14Cerebmspinal fluid amyloid p and tau in I,RRK2 mutation carriers显示文摘Aasly JO Shi M Sossi V 0,,01:1
15Toxoplasma gondii Isolates From Free-Range Chickens From the Northeast Region of Brazil显示文摘de Oliveira L N Costa L M de Melo C F Silva J C Ramos Bevilaqua C M L Azevedo S S Muradian V Araújo D A F V Dubey J P Gennari S M 2009The Journal of Parasitology2009,,1:1
16Oncologic outcomes at 10 years following robotic radical prostatectomy 显示文摘Diaz M Peabody JO Kapoor V 2015Eur Urol2015,67,8:1
17Inferring human mobility using communication patterns显示文摘Palchykov V Mitrovic M Jo H H 2014Scientific reports2014,,4:1
18Softwood hemicellulose-degrading enzymes from Aspergillus niger:Purification and properties of a β-mannanase显示文摘Pia A Arthur V Jo zsef M 1998Journal of Biotechnology1998,63,3:1
19uPAR induces epithelial-mes- enchymal transition in hypoxic breast cancer cells显示文摘Lester P D Jo M Montel V 2007J Cell Biol2007,178,3:1
20uPAR induces epithelial-mesencbymal transition in hypoxic breast cancer cells显示文摘Lester RD Jo M Montel V 2007J Cell Biol2007,178,3:1
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