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| 1 | Magnetic resonance imaging and multi-detector computed tomography assessment of extracellular compartment in ischemic and non-ischemic myocardial pathologies显示文摘Myocardial pathologies are major causes of morbidity and mortality worldwide. Early detection of loss of cellular integrity and expansion in extracellular volume(ECV) in myocardium is critical to initiate effective treatment. The three compartments in healthy myocardium are: intravascular(approximately 10% of tissue volume), interstitium(approximately 15%) and intracellular(approximately 75%). Myocardial cells, fibroblasts and vascular endothelial/smooth muscle cells represent intracellular compartment and the main proteins in the interstitium are types Ⅰ/Ⅲ collagens. Microscopic studies have shown that expansion of ECV is an important feature of diffuse physiologic fibrosis(e.g., aging and obesity) and pathologic fibrosis [heart failure, aortic valve disease, hypertrophic cardiomyopathy, myocarditis, dilated cardiomyopathy, amyloidosis, congenital heart disease, aortic stenosis, restrictive cardiomyopathy(hypereosinophilic and idiopathic types), arrythmogenic right ventricular dysplasia and hypertension]. This review addresses recent advances in measuring of ECV in ischemic and non-ischemic myocardial pathologies. Magnetic resonance imaging(MRI) has the ability to characterize tissue proton relaxation times(T1, T2, and T2*). Proton relaxation times reflect the physical and chemical environments of water protons in myocardium. Delayed contrast enhanced-MRI(DE-MRI) and multi-detector computed tomography(DE-MDCT) demonstrated hyper-enhanced infarct, hypo-enhanced microvascular obstruction zone and moderately enhanced peri-infarct zone, but are limited for visualizing diffuse fibrosis and patchy microinfarct despite the increase in ECV. ECV can be measured on equilibrium contrast enhanced MRI/MDCT and MRI longitudinal relaxation time mapping. Equilibrium contrast enhanced MRI/MDCT and MRI T1 mapping is currently used, but at a lower scale, as an alternative to invasive sub-endomyocardial biopsies to eliminate the need for anesthesia, coronary catheterization and possibility of tissue sampling error. Similar to delayed contrast enhancement, equilibrium contrast enhanced MRI/MDCT and T1 mapping is completely noninvasive and may play a specialized role in diagnosis of subclinical and other myocardial pathologies. DE-MRI and when T1-mapping demonstrated sub-epicardium, sub-endocardial and patchy mid-myocardial enhancement in myocarditis, Behcet's disease and sarcoidosis, respectively. Furthermore, recent studies showed that the combined technique of cine, T2-weighted and DE-MRI technique has high diagnostic accuracy for detecting myocarditis. When the tomographic techniques are coupled with myocardial perfusion and left ventricular function they can provide valuable information on the progression of myocardial pathologies and effectiveness of new therapies. | Maythem Saeed Steven W Hetts Robert Jablonowski Mark W Wilson | 2014 | World Journal of Cardiology2014，6，11： | 4 |
| 2 | 胶管胶带用硫化剂和防老剂显示文摘越来越高的汽车发动机温度对在汽车中使用的胶管和胶带用聚合物提出了更严格的要求。本文综述了胶管和胶带中使用的聚合物,并针对提高耐热、耐屈挠疲劳和耐臭氧老化性能讨论了每一种聚合物用的硫化体系和防老剂搭配。 | Sinha D P Jablonowski Tom Ohm Bob Vanis Vern 黄向前 | 2002 | 橡胶工业2002，49，12： | 2 |
| 3 | 实物期权整合模型在石油勘探开发项目中的应用显示文摘基于决策树和二叉树的整合模型是目前比较可行的一种实物期权定价方法。该方法把影响项目经济价值的所有不确定性分为两类——市场不确定性和技术不确定性。本文利用该方法对一个位于阿塞拜疆的实际石油项目进行了评价,识别出了对项目经济性具有较大影响的5个不确定性因素(输入变量):油价、投产初期产量(Initial Production Rate)、递减率(Decline Rate)、总投资(CAPEX)和操作成本(Variable Cost)。通过分析,该项目可能存在多种实物期权。利用该整合模型并应用DPL软件建模估算了这一石油项目的扩张期权、放弃期权和复合期权的价值。 | 郭勤涛 Christopher J. Jablonowski | 2008 | 国际石油经济2008，16，5： | 2 |
| 4 | 混炼型聚氨酯胶的过氧化物硫化显示文摘聚氨酯橡胶是一种特种橡胶,它用于许多普通橡胶制品中,如滑冰鞋的轮子、传送带或胶带、橡胶包覆胶辊和其它能利用聚氨酯性能的领域。 | Thomas L. Jablonowski 刘霞 | 2000 | 橡胶参考资料2000，30，5： | 2 |
| 5 | SH2 domains recognize contextual peptide sequence information to determine selectivity 显示文摘 | Liu B A Jablonowski K Shah E E | 2010 | Mol Cell Proteomics2010，9，11： | 1 |
| 6 | Still present after all these years: persistence plus potential toxicity raise ques- tions about the use of atrazine显示文摘 | Jablonowski N D Sch/iffer A Burauel P | 2011 | Environmental Science and Pollution Research2011，18，2： | 1 |
| 7 | Radical and sparing surgical treatment of patients with upper urinary tract transitional cell carcinomas (UUT- TCC)preliminary results显示文摘 | Jablonowski Z Kedzierski R Sosnowski M | 2011 | Cent European J Urol2011，64，2： | 1 |
| 8 | The first potent and selective non-imidazole human histamine H4-receptor antagonists显示文摘 | Grice CA Chai W | 2003 | J Med Chem2003，46，19： | 1 |
| 9 | A comparison of two shallow-water models with nonconforming adaptive grids显示文摘 | St--Cyr A C Jablonowski J M Dennis | 2008 | MonWeaRev2008，136，6： | 1 |
| 10 | Stavudine and the Peripheral Nerve in HIV-1 Infected Patients显示文摘 | Giesen H J Hefter H Jablonowski H | 1999 | J Neurol1999，246，3： | 1 |
| 11 | A baroclinic instability test case for atmospheric model dynamical cores 显示文摘 | Jablonowski C D L Williamson | 2006 | Quart J Roy Meteor Soc2006，132，10： | 1 |
| 12 | Beam deflcction at high accuracy and precision 显示文摘 | D P Jablonowski J Raamot | 1976 | SPIE1976，84，： | 1 |
| 13 | Inappropriate emergency department visits显示文摘 | Buesching DP Jablonowski A Vesta E | | 0，，07： | 1 |
| 14 | Rapid immobilization of applied nitrogen in salinealkaline soils显示文摘 | Garcia-Mendoza M Jablonowski N | 2003 | Plant and soil2003，256，： | 1 |
| 15 | Developing probabilistic well construction estimates using regression analysis显示文摘 | Christopher J Jablonowski Douglas P MacEachern | 2010 | Energy Exploration & Exploitation2010，27，6： | 1 |
| 16 | Candida albicans- epithelial interactions : dissecting the roles of active penetration, induced endocytosis and host factors on the infection process 显示文摘 | Wachtler B Citiulo F Jablonowski N | 2012 | PLoS One2012，7，36： | 1 |
| 17 | Multidetector CT meas urement of myocardial extracellular volume in acute patchy and contiguous infarction: validation with microscopic measurement 显示文摘 | Jablonowski R Wilson MW Do L | 2015 | Radiology2015，274，2： | 1 |
| 18 | Radical and sparingsurgical treatment of patients with upper urinary tract transitionalcell carcinomas ( UUT-TCC)-preliminary results 显示文摘 | Jablonowski Z Kedzierski R Sosnowski M | 2011 | Cent Euro-pean J Urol2011，64，2： | 1 |
| 19 | Persistence of ^14C-labeled atrazine and its residues in a field lysimeter soil after 22 years显示文摘 | JABLONOWSKI ND KOPPCHEN S HOFMANN D | 2009 | Environ Pollut2009，157，7： | 1 |
| 20 | Polymorphis- ms of NRF2 and NRF2 target genes in urinary bladder cancer patients显示文摘 | Reszka E Jablonowski Z Wieczorek E | 2014 | J Cancer Res Clin Oncol2014，140，10： | 1 |
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