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| 1 | Transjugular intrahepatic portosystemic shunt vs endoscopic therapy in preventing variceal rebleeding显示文摘AIM:To compare early use of transjugular intrahepatic portosystemic shunt(TIPS) with endoscopic treatment(ET) for the prophylaxis of recurrent variceal bleeding.METHODS:In-patient data were collected from 190 patients between January 2007 and June 2010 who suffured from variceal bleeding.Patients who were older than 75 years;previously received surgical treatment or endoscopic therapy for variceal bleeding;and complicated with hepatic encephalopathy or hepatic cancer,were excluded from this research.Thirty-five cases lost to follow-up were also excluded.Retrospective analysis was done in 126 eligible cases.Among them,64 patients received TIPS(TIPS group) while 62 patients received endoscopic therapy(ET group).The relevant data were collected by patient review or telephone calls.The occurrence of rebleeding,hepatic encephalopathy or other complications,survival rateand cost of treatment were compared between the two groups.RESULTS:During the follow-up period(median,20.7 and 18.7 mo in TIPS and ET groups,respectively),rebleeding from any source occurred in 11 patients in the TIPS group as compared with 31 patients in the ET group(Kaplan-Meier analysis and log-rank test,P = 0.000).Rebleeding rates at any time point(6 wk,1 year and 2 year) in the TIPS group were lower than in the ET group(Bonferroni correction α' = α/3).Eight patients in the TIPS group and 16 in the ET group died with the cumulative survival rates of 80.6% and 64.9%(Kaplan-Meier analysis and log-rank test c2 = 4.864,P = 0.02),respectively.There was no significant difference between the two groups with respect to 6-wk survival rates(Bonferroni correction α' = α/3).However,significant differences were observed between the two groups in the 1-year survival rates(92% and 79%) and the 2-year survival rates(89% and 64.9%)(Bonferroni correction α' = α/3).No significant differences were observed between the two treatment groups in the occurrence of hepatic encephalopathy(12 patients in TIPS group and 5 in ET group,KaplanMeier analysis and log-rank test,c2 = 3.103,P = 0.08).The average total cost for the TIPS group was higher than for ET group(Wilcxon-Mann Whitney test,52 678 RMB vs 38 844 RMB,P < 0.05),but hospitalization frequency and hospital stay during follow-up period were lower(Wilcxon-Mann Whitney test,0.4 d vs 1.3 d,P = 0.01;5 d vs 19 d,P < 0.05).CONCLUSION:Early use of TIPS is more effective than endoscopic treatment in preventing variceal rebleeding and improving survival rate,and does not increase occurrence of hepatic encephalopathy. | Hui Xue Meng Zhang Jack XQ Pang Fei Yan Ying-Chao Li Liang-Shan Lv Jia Yuan Muna Palikhe Wei-Zhi Li Zhi-Lun Wang | 2012 | World Journal of Gastroenterology2012，18，48： | 17 |
| 2 | Regulation of Seed Vigor by Manipulation of Raffinose Family Oligosaccharides in Maize and Arabidopsis thaliana显示文摘棉白糖家庭 oligosaccharides (RFO ) 在许多植物种类在成熟干燥期间在种子积累。然而, RFO 是否在建立种子活力有一个角色,仍然保持不清楚。GALACTINOL SYNTHASE (GOLS ) ,棉白糖 SYNTHASE (RS ) ,和 STACHYOSE SYNTHASE (圣) 是为 RFO 负责的酶 ? 在植物的生合成。有趣地,仅仅棉白糖在玉米种子被检测,并且唯一的玉米 RS 基因(ZmRS ) 被识别。在这研究,我们发现二独立 mutator (亩) 打断了 zmrs 线,不包含棉白糖但是 hyperaccumulating galactinol, ? 显著地减少了种子活力,与空 segregant 控制相比。不同于玉米, Arabidopsis thaliana 种子包含几 RFO (棉白糖, stachyose,和 verbascose ) 。A 的操作。thaliana RFO ? 由 overexpressing ZmGOLS2, ZmRS,或 AtSTS 的内容表明了那 co-overexpression ZmGOLS2 和 ZmRS,或 ZmGOLS2 的 overexpression 独自一个,显著地增加了 RFO 的全部的内容并且提高了 Arabidopsis 种子活力。令人惊讶地,当 ZmRS 的 overexpression 增加了种子棉白糖内容时,它的 overexpression 戏剧性地减少了种子活力并且减少了 galactinol, stachyose,和 verbascose 的种子数量。相反, atrs5 异种种子类似于关于种子活力和 RFO 内容的野类型的那些,除了 stachyose 它在 atrs5 种子积累了。全部的 RFO, RFO/sucrose 比率,然而并非绝对单个 RFO ? 数量,断然与 A 相关。thaliana 种子活力, stachyose 和 verbascose 多于棉白糖作出贡献到。一起拿,这些结果提供新卓见进种子活力的规章的机制并且在 monocot 和 dicot 在 modulating 种子活力为 RFO 揭示不同要求。 | Tao Li Yumin Zhang Dong Wang Ying Liu Lynnette M.A. Dirk Jack Goodman A. Bruce Downie Jianmin Wang Guoying Wang Tianyong Zhao | 2017 | Molecular Plant2017，10，12： | 13 |
| 3 | Mechanisms and clinical significance of quality of final kissing balloon inflation in patients with true bifurcation lesions treated by crush stenting technique显示文摘背景为吻的出现负责的机制未得到满足(KUS ) 在古典压碎 stenting 以后结果仍然保持不清楚。现在的学习瞄准了分析机制和 KUS 的临床的意义。有真分叉损害的 213 个病人与古典压碎 stenting 和最后的吻汽球通货膨胀( FKBI )对待的方法根据分支给视觉评价换新电线由估计了的方面的位置被分到上面、中间、更低的组,量的冠的分析( QCA )和 intravascular 超声( IVUS )。Angiographic 后续在 12 months.Results 被索引上面的组被 55.53 的一个更大的分叉角度描绘吗? | ZHANG Jun-jie CHEN Shao-liang YE Fei YANG Song KAN Jing LIU Yue-qiang ZHOU Yong SUN Xue-wen ZHANG Ai-ping WANG Xin CHEN Jack | 2009 | Chinese Medical Journal2009，，18： | 8 |
| 4 | Autonomic Regulation of the Cardiovascular System: Diseases,Treatments, and Novel Approaches显示文摘The autonomic nervous system(ANS)integrates the involuntary physiological activities of visceral organs that are vital for survival.In particular,the ANS controls heart rate,blood pressure,breathing,gastrointestinal contraction and secretion,and electrolyte and fluid homeostasis.Many studies have focused on understanding the neural mechanisms of autonomic dysfunction or neuropathy in pathophysiological states including hypertension,heart failure. | Zixi Jack Cheng Renjun Wang Qing-Hui Chen | 2019 | Neuroscience Bulletin2019，35，1： | 3 |
| 5 | Agricultural Risk Factors Influence Microbial Ecology in Honghu Lake显示文摘Agricultural activities, including stock-farming, planting industry, and fish aquaculture,can affect the physicochemical and biological characters of freshwater lakes. However, the effects of pollution producing by agricultural activities on microbial ecosystem of lakes remain unclear.Hence, in this work, we selected Honghu Lake as a typical lake that is influenced by agriculture activities. We collected water and sediment samples from 18 sites, which span a wide range of areas from impacted and less-impacted areas. We performed a geospatial analysis on the composition of microbial communities associated with physicochemical properties and antibiotic pollution of samples. The co-occurrence networks of water and sediment were also built and analyzed. Our results showed that the microbial communities of impacted and less-impacted samples of water were largely driven by the concentrations of TN, TP, NO_3^--N, and NO_2^--N, while those of sediment were affected by the concentrations of Sed-OM and Sed-TN. Antibiotics have also played important roles in shaping these microbial communities: the concentrations of oxytetracycline and tetracycline clearly reflected the variance in taxonomic diversity and predicted functional diversity between impacted and less-impacted sites in water and sediment samples, respectively. Furthermore, for samples from both water and sediment, large differences of network topology structures between impacted and less-impacted were also observed. Our results provide compelling evidence that the microbial community can be used as a sentinel of eutrophication and antibiotics pollution risk associated with agricultural activity; and that proper monitoring of this environment is vital to maintain a sustainable environment in Honghu Lake. | Maozhen Han Melissa Dsouza Chunyu Zhou Hongjun Li Junqian Zhang Chaoyun Chen Qi Yao Chaofang Zhong Hao Zhou Jack A Gilbert Zhi Wang Kang Ning | 2019 | Genomics, Proteomics & Bioinformatics2019，17，1： | 3 |
| 6 | Long-term safety of laser in situ keratomileusis in eyes with thin corneas: 5-year follow-up显示文摘● AIM: To investigate the long term(≥5 y) efficacy, predictability, and safety of laser in situ keratomileusis(LASIK) in eyes with thin corneas [central corneal thickness(CCT) <500 μm].● METHODS: A total of 339 patients met the criteria of this study. Finally, 175 eyes of 89 patients who had thin corneas and underwent LASIK≥5 y ago returned to our clinic and included in this study. Preoperative parameters recorded included uncorrected visual acuity(UCVA), corrected distance visual acuity(CDVA), manifest refraction, CCT and corneal topography. At returning visits, in addition to visual acuity and manifest refraction, ultrasound CCT and corneal topography were performed. Optical coherence tomography was used to measure the CCT, LASIK flap thickness, and residual stromal bed thickness(RSBT). Safety index, efficacy index, percentage of eyes within ±0.5 D and ±1.0 D of refraction, percent tissue altered(PTA), and percentage stromal bed thickness(PSBT) were calculated.● RESULTS: The safety index was 1.09 and efficacy index was 0.99. The percentages of eyes within ±0.5 D and ±1.0 D were 71.2% and 87.7%, respectively. The mean PTA was 40%±6%(range 20% to 55%); 76 eyes(43.4%) had PTA <40% and 99 eyes(56.6%) had PTA≥40%. The mean RSBT was 303±27 μm(range 240 to 390 μm), and 2 eyes had RSBT<250 μm. The mean PSBT was 61%±9%(range 51% to 85%). No eyes developed ectasia. ● CONCLUSION: In this cohort with the PSBT of 50% or more, LASIK is safe with follow-up for at least 5 y. | Yao-Wen Song Rui He Jack X.Ma Douglas D.Koch Li Wang | 2018 | International Journal of Ophthalmology(English edition)2018，11，7： | 3 |
| 7 | 美国俄亥俄河流域水质卫生委员会的运作显示文摘在供水体系中,水源水质的安全直接影响着后续供水处理系统的成本和效果,以及用水居民的日常生活和健康。当前我国城市饮用水供应很大一部分来自地表水体(河流、水库、湖泊等),而其中大江大河的水质安全因为邻接众多工厂企业,牵涉到跨地域和行政区划的管理与协调,更是给环境部门全面有效的监测与管理提出了挑战。平时环保风险意识的淡薄, | 张强 孟远航 Jack Wang | 2006 | 世界环境2006，，1： | 2 |
| 8 | Relationship between mode of sport training and general cognitive performance显示文摘Purpose: To investigate whether athletes who engage in different modes of sports training correspondingly exhibit different patterns of performance on general cognition tasks.Methods: Sixty participants were recruited into an endurance, motorically complex, or control group, and were administered a series of physical tests and neuropsychological assessments.Results: Athletes in the endurance group demonstrated the highest levels of cardiovascular fitness and those in the motorically complex group exhibited the highest levels of motor fitness. Nonetheless, no differences in cognitive performance were observed between the 3 groups.Conclusion: These findings indicate that the mode of sport training, which results in either high cardiovascular or high motor fitness, bears no relationship to measures of general cognition in elite athletes. The present findings suggest that coaches and athletic trainers should be encouraged to monitor athletes' stress levels during training in order to maximize the beneficial effects of such training on general cognitive performance. | Erik Chih-Hung Chang Chien-Heng Chu Costas I.Karageorghis Chun-Chih Wang Jack Han-Chao Tsai Yung-Shun Wang Yu-Kai Chang | 2017 | Journal of Sport and Health Science2017，6，1： | 2 |
| 9 | Antifungal and antiviral products of marine organisms显示文摘 | Randy Chi Fai Cheung Jack Ho Wong Wen Liang Pan Yau Sang Chan Cui Ming Yin Xiu Li Dan He Xiang Wang Evandro Fei Fang Sze Kwan Lam Patrick Hung Kui Ngai Li Xin Xia Fang Liu Xiu Yun Ye Guo Qing Zhang Qing Hong Liu Ou Sha Peng Lin Chan Ki Adnan A Bekhit Alaa | 2014 | Applied Microbiology and Biotechnology2014，，8： | 2 |
| 10 | Deep Learning for Real-Time Crime Forecasting and Its Ternarization显示文摘Real-time crime forecasting is important.However,accurate prediction of when and where the next crime will happen is difficult.No known physical model provides a reasonable approximation to such a complex system.Historical crime data are sparse in both space and time and the signal of interests is weak.In this work,the authors first present a proper representation of crime data.The authors then adapt the spatial temporal residual network on the well represented data to predict the distribution of crime in Los Angeles at the scale of hours in neighborhood-sized parcels.These experiments as well as comparisons with several existing approaches to prediction demonstrate the superiority of the proposed model in terms of accuracy.Finally,the authors present a ternarization technique to address the resource consumption issue for its deployment in real world.This work is an extension of our short conference proceeding paper[Wang,B.,Zhang,D.,Zhang,D.H.,et al.,Deep learning for real time Crime forecasting,2017,ar Xiv:1707.03340]. | Bao WANG Penghang YIN Andrea Louise BERTOZZI P.Jeffrey BRANTINGHAM Stanley Joel OSHER Jack XIN | 2019 | Chinese Annals of Mathematics,Series B2019，40，6： | 2 |
| 11 | Development of Empirical Models for Surface Roughness Prediction in Fish Turning 显示文摘 | WANG X FENG JACK C X | 2002 | International Journal of Advanced Manufacturing Technology2002，20，5： | 1 |
| 12 | Genetic mapping of 66 new microsatellite (SSR) loci in bread wheat显示文摘 | P. Gupta H. Balyan K. Edwards P. Isaac V. Korzun M. R?der M.–F. Gautier P. Joudrier A. Schlatter J. Dubcovsky R. De la Pena M. Khairallah G. Penner M. Hayden P. Sharp B. Keller R. Wang J. Hardouin P. Jack P. Leroy | 2002 | Theoretical and Applied Genetics (-)2002，，2： | 1 |
| 13 | Whole-body skeletal muscle mass:development and validation of total-body potassium prediction models显示文摘 | Zimian Wang Shankuan Zhu Jack Wang | 2003 | Am J Clin Nutrition2003，77，： | 1 |
| 14 | Development of Empirical Models for Surface Roughness Prediction in Finish Turning显示文摘 | JACK C X WANG X | 2002 | International Journal of Advanced Manufacture Technolo- gy2002，256，34： | 1 |
| 15 | Unmet needs as indicator of improving chronic care delivery system in China显示文摘In 2009, China strengthened its public health service system. Since then, the country has made remarkable achievements in community-based chronic disease prevention and control;however, certain groups still have unmet needs. During 2019 to 2029, China will consolidate the top-level design of its medical health system. During this period, the coordination of department policies, improvement of service delivery mechanisms, building an integrated health service system, and other issues will be highlighted. This study will provide a basis for designing China’s chronic disease prevention and control system during the next stage of development. We will consider the unmet needs of patients with chronic diseases as an indicator for remodeling the prediction system in combination with the elements and structural theories of complex health systems. In this article, we first introduce the definition and measurement methods of unmet needs. Second, we identify the existing unmet needs found among patients with chronic diseases with reference to the chronic disease prevention and control policies of China as well as current service items. Finally, we propose the design of community chronic disease service package for the next development stage based on unmet needs of patients with chronic diseases. We also provide suggestions for how to improve China’s chronic care delivery system. | Xia-Tong Ke Chun-Lu Wang Jack Warren Salmon Wen-Xi Tang | 2021 | Chronic Diseases and Translational Medicine2021，7，1： | 1 |
| 16 | Finding the medial axis of a simple polygon in linear time 显示文摘 | Chin Francis Snoeyink Jack Wang Caoan | 1999 | Discrete and Computational Geometry1999，21，3： | 1 |
| 17 | In vivo biocompatibility and degradability of a Zn-Mg-Fe alloy osteosynthesis system显示文摘Zinc is generally considered to be one of the most promising materials to be used in biodegradable implants,and many zinc alloys have been optimized to improve implant biocompatibility,degradation,and mechanical properties.However,long-term degradation leads to the prolonged presence of degradation products,which risks foreign body reactions.Herein,we investigated the in vivo biocompatibility and degradation of a biodegradable Zn-Mg-Fe alloy osteosynthesis system in the frontal bone,mandible,and femur in beagles for 1 year.Results of the routine blood,biochemical,trace element,and histological analyses of multiple organs,peripheral blood CD4/CD8a levels,and serum interleukin 2 and 4 levels showed good biocompatibility of the Zn-Mg-Fe alloy.Zinc content analysis revealed zinc accumulation in adjacent bone tissue,but not in the liver,kidney,and spleen,which was related to the degradation of the Zn-Mg-Fe alloy.The alloy demonstrated a uniform slowing degradation rate in vivo.No degradation differences in the frontal bone,mandible,and femur were observed.The degradation products included zinc oxide[ZnO],zinc hydroxide[Zn(OH)_(2)],hydrozincite[Zn_(5)(OH)_(6)(CO_(3))_(2)],and hopeite[Zn_(3)(PO_(4))_(2)⋅4H_(2)O].The good biocompatibility and degradation properties of the Zn-Mg-Fe alloy render it a very attractive osteosynthesis system for clinical applications. | Xiaoxi Shao Xiang Wang Fangfang Xu Taiqiang Dai Jack G.Zhou Jiang Liu Kun Song Lei Tian Bin Liu Yanpu Liu | 2022 | Bioactive Materials2022，7，1： | 1 |
| 18 | Genetic mapping of 66 new microsatellite (SSR) loci in bread wheat显示文摘 | P. Gupta H. Balyan K. Edwards P. Isaac V. Korzun M. R?der M.–F. Gautier P. Joudrier A. Schlatter J. Dubcovsky R. De la Pena M. Khairallah G. Penner M. Hayden P. Sharp B. Keller R. Wang J. Hardouin P. Jack P. Leroy | 2002 | Theoretical and Applied Genetics (-)2002，，2： | 1 |
| 19 | Water relations and canopy charac- teristics of tall rescue cultivars during and after drought stress显示文摘 | Huang B Jack F Wang B | 1998 | Hort Sci1998，，33： | 1 |
| 20 | Performance of melon hybrids derived from parents of diverse geographic Origins显示文摘 | Feishi Luan Yunyan Sheng Yuhan Wang Jack E. Staub | 2010 | Euphytica2010，，1： | 1 |
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