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| 1 | Impact and clinical usefulness of genetic data in the surgical management of colorectal cancer liver metastasis: a narrative review显示文摘Importance:In patients who undergo surgery for colorectal cancer liver metastases(CRLM),a number of somatic mutations have been associated with worse overall(OS)and recurrence-free survival(RFS).Although useful,an association with prognosis does not necessarily equate to an impact on surgical management.Objective:The aim of this review was to investigate whether the best-studied somatic mutations impact surgical management of CRLM by informing:(I)post-hepatectomy surveillance;(II)selection of surgical technique;(III)selection of optimal margin width;and(IV)selection of patients for surgery.Lastly,we discuss the refinement of genetic data from overall mutation status to specific variants,as well as lesser studied somatic mutations.Evidence Review:We conducted a computerized search using PubMed and Google Scholar for reports published so far,using mesh headings and keywords related to genetic data and CRLM.Findings:Genetic data may impact surgical management of CRLM in three ways.Firstly,KRAS mutations can predict lung recurrences.Secondly,KRAS mutations may help tailor margin width.Thirdly,KRAS mutations may help tailor surgical technique.Conclusions:Although genetic data may impact post-hepatectomy surveillance,selection of surgical technique and optimal margin width,their use to guide surgical selection remains elusive,as the data cannot support denying surgery to patients according to their somatic mutation profile. | Georgios Antonios Margonis Martin E.Kreis Jaeyun Jane Wang Carsten Kamphues Christopher L.Wolfgang Matthew J.Weiss | 2020 | Hepatobiliary Surgery and Nutrition2020，9，6： | 3 |
| 2 | Recent progress in the synthesis of porous carbon materials显示文摘 | Jinwoo L Jaeyun K Taeghwan H | 2006 | Adv Mater2006，18，： | 1 |
| 3 | Trend of Developing Aqueous Liquid and Gel Electrolytes for Sustainable,Safe,and High‑Performance Li‑Ion Batteries显示文摘Current lithium-ion batteries(LIBs)rely on organic liquid electrolytes that pose significant risks due to their flammability and toxicity.The potential for environmental pollution and explosions resulting from battery damage or fracture is a critical concern.Water-based(aqueous)electrolytes have been receiving attention as an alternative to organic electrolytes.However,a narrow electrochemicalstability window,water decomposition,and the consequent low battery operating voltage and energy density hinder the practical use of aqueous electrolytes.Therefore,developing novel aqueous electrolytes for sustainable,safe,high-performance LIBs remains challenging.This Review first commences by summarizing the roles and requirements of electrolytes–separators and then delineates the progression of aqueous electrolytes for LIBs,encompassing aqueous liquid and gel electrolyte development trends along with detailed principles of the electrolytes.These aqueous electrolytes are progressed based on strategies using superconcentrated salts,concentrated diluents,polymer additives,polymer networks,and artificial passivation layers,which are used for suppressing water decomposition and widening the electrochemical stability window of water of the electrolytes.In addition,this Review discusses potential strategies for the implementation of aqueous Li-metal batteries with improved electrolyte–electrode interfaces.A comprehensive understanding of each strategy in the aqueous system will assist in the design of an aqueous electrolyte and the development of sustainable and safe high-performance batteries. | Donghwan Ji Jaeyun Kim | 2024 | Nano-Micro Letters2024，16，1： | 1 |
| 4 | 显示文摘 | Jaeyun M Hanshin C Hyungjun K | 2002 | Surface and Coatings Technology2002，155，： | 1 |
| 5 | Multifunctional uniform nanoparticles composed of a magnetite nanocrystal core and a mesoporous silica shell for magnetic resonance and fluorescence im- aging and for drug delivery 显示文摘 | KIM Jaeyun KIM Hoe Suk LEE Nohyun | 2008 | Angew Chem Int Ed2008，47，： | 1 |
| 6 | Generalized fabrication of multifunctional nanoparticle assemblies on silica spheres显示文摘 | JAEYUN K LEE J E LEE J | 2006 | Angewandte Chemie International Edition2006，45，： | 1 |
| 7 | Systems Approach to Neurodegenerative Disease Biomarker Discovery显示文摘 | Christopher Lausted Inyoul Lee Yong Zhou Shizhen Qin Jaeyun Sung Nathan D. Price Leroy Hood Kai Wang | 2014 | Annual Review of Pharmacology and Toxicology2014，，： | 1 |
| 8 | Direct synthesis of uniform mesoporous carbons from the carbonization of as-synthesized silica/triblock copolymer nanocomposites显示文摘 | JAEYUN KIM JINWOO LEE TAEGHWAN HYEON | 2004 | Carbon2004，，42： | 1 |
| 9 | Recent Progress in the Synthesis of Porous Carbon Materials显示文摘 | Jinwoo L Jaeyun K Taeghwan H | 2006 | Adv Mater2006，18，20： | 1 |
| 10 | Magnetic Fluorescent Delivery Vehicle Using Uniform Mesoporous Silica Spheres Embedded with Monodisperse Magnetic and Semiconductor Nanocrystals显示文摘 | JAEYUN K JI E L JINWOO L | 2006 | J Am Chem Soc2006，128，3： | 1 |
| 11 | Effect of pore structure of macroporous poly ( Lactide-co-GIycolide ) scaffolds on the in vivo enrichment of dendritic cells显示文摘 | Jaeyun Kim Weiwei Aileen Li Warren Sands | 2014 | ACS Appl Mater In- terfaces2014，6，11： | 1 |
| 12 | The effects of heat treatment on the phase transformation behavior of plasma- sprayed stabilized ZrO2 coatings 显示文摘 | Moon Jaeyun Choi Hanshin Kim Hyungjun | 2002 | Surf Coat Technol2002，155，： | 1 |
| 13 | Customized lipid-coated magnetic mesoporous silica nanoparticle doped with ceria nanoparticles for theragnosis of intracerebral hemorrhage显示文摘Intracerebral 出血(ICH ) ,在大脑以内由一根动脉的突然的破裂引起了,是击的一种破坏子类型,它当前没有有效处理。在 ICH 以后发生在 peri-hematomal 区域的强烈煽动性的反应自己比 hematoma 更有害,导致随后的大脑浮肿和神经恶化。因此,我们开发了与 ceria nanoparticles (CeNPs ) 做的类脂化合物涂的磁性的 mesoporous 硅石 nanoparticles,作为 LMC 缩短了,它两个都有有势力经由清除的反煽动性的治疗学的效果在在 peri-hematomal 区域增加磁性的回声成像改进的功效的反应的氧种类和帮助。LMC 由支持 nanoparticle 的类脂化合物 bilayers,为反应的氧种类清除与大量 CeNPs 被装载,和为磁性的回声成像的氧化铁 nanoparticles 对比的 mesoporous 硅石组成。与 CeNPs 装载的 LMC 在 vitro 展出了强壮的抗氧化、反煽动性的活动。在啮齿类动物 ICH 模型, intracerebrally 注射了 LMC 到达了 peri-hematomal 区域并且被巨噬细胞吞没,它被大脑的磁性的回声成像清楚地设想。而且, LMC 减少了煽动性的巨噬细胞渗入,并且显著地因此减少了大脑浮肿。最后, LMC 处理显著地与 ICH 改进了动物的神经结果。因此, LMC 是成功地在 ICH 显示出 theragnostic 效果的第一 nanobiomaterial。 | Bong Geun Cha Han-Gil Jeong Dong-Wan Kang Myong-Joo Nam Chi Kyung Kim Do Yeon Kim In-Young Choi Seul Ki Ki Song I Kim Ju hee Han Jaeyun Kim Seung-Hoon Lee | 2018 | Nano Research2018，11，7： | 0 |
| 14 | Rapid determination of lithium-ion battery degradation: High C-rate LAM and calculated limiting LLI显示文摘Herein,incremental capacity-differential voltage (IC-DV) at a high C-rate (HC) is used as a non-invasive diagnostic tool in lithium-ion batteries,which inevitably exhibit capacity fading caused by multiple mechanisms during charge/discharge cycling.Because battery degradation modes are complex,the simple output of capacity fading does not yield any useful data in that respect.Although IC and DV curves obtained under restricted conditions (<0.1C,25℃) were applied in non-invasive analysis for accurate observation of degradation symptoms,a facile,rapid diagnostic approach without intricate,complex calculations is critical in on-board applications.Herein,Li Ni_(0.5)Mn_(0.3)Co_(0.2)O_(2)(NMC532)/graphite pouch cells were cycled at 4 and 6C and the degradation characteristics,i.e.,loss of active materials (LAM) and loss of lithium inventory (LLI),were parameterized using the IC-DV curves.During the incremental current cycling,the initial steep LAM and LLI slopes underwent gradual transitions to gentle states and revealed the gap between low-and high-current measurements.A quantitative comparison of LAM at high and low C-rate showed that a IC;revealed the relative amount of available reaction region limited by cell polarization.However,this did not provide a direct relationship for estimating the LAM at a low C-rate.Conversely,the limiting LLI,which is calculated at a C-rate approaching 0,was obtained by extrapolating the LLI through more than two points measured at high C-rate,and therefore,the LLI at 0.1C was accurately determined using rapid cycling. | Gyuwon Seo Jaeyun Ha Moonsu Kim Jihyeon Park Jaewon Lee Eunoak Park Sungyool Bong Kiyoung Lee Soon Jong Kwon Seung-pil Moon Jinsub Choi Jaeyoung Lee | 2022 | Journal of Energy Chemistry2022，31，4： | 0 |
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