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| 1 | Optimal initiation of Helicobacter pylori eradication in patients with peptic ulcer bleeding显示文摘AIM:To evaluate when Helicobacter pylori(H.pylori)eradication therapy(ET)should be started in patients with peptic ulcer bleeding(PUB).METHODS:Clinical data concerning adults hospitalizedwith PUB were retrospectively collected and analyzed.Age,sex,type and stage of peptic ulcer,whether endoscopic therapy was performed or not,methods of H.pylori detection,duration of hospitalization,and specialty of the attending physician were investigated.Factors influencing the confirmation of H.pylori infection prior to discharge were determined using multiple logistic regression analysis.The H.pylori eradication rates of patients who received ET during hospitalization and those who commenced ET as outpatients were compared.RESULTS:A total of 232 patients with PUB were evaluated for H.pylori infection by histology and/or rapid urease testing.Of these patients,53.7%(127/232)had confirmed results of H.pylori infection prior to discharge.In multivariate analysis,duration of hospitalization and ulcer stage were factors independently influencing whether H.pylori infection was confirmed before or after discharge.Among the patients discharged before confirmation of H.pylori infection,13.3%(14/105)were lost to follow-up.Among the patients found to be H.pylori-positive after discharge,41.4%(12/29)did not receive ET.There was no significant difference in the H.pylori eradication rate between patients who received ET during hospitalization a n d t h o s e w h o c o m m e n c e d E T a s o u t p a t i e n t s[intention-to-treat:68.8%(53/77)vs 60%(12/20),P=0.594;per-protocol:82.8%(53/64)vs 80%(12/15),P=0.723].CONCLUSION:Because many patients with PUB who were discharged before H.pylori infection status was confirmed lost an opportunity to receive ET,we should confirm H.pylori infection and start ET prior to discharge. | Hyuk Yoon Dong Ho Lee Eun Sun Jang Jaihwan Kim Cheol Min Shin Young Soo Park Jin-Hyeok Hwang Jin-Wook Kim Sook-Hayng Jeong Nayoung Kim | 2015 | World Journal of Gastroenterology2015，21，8： | 7 |
| 2 | Clinical features of 20 patients with curatively resected biliary neuroendocrine tumours显示文摘 | Jaihwan Kim Woo Jin Lee Sang Hyub Lee Kyoung Bun Lee Ji Kon Ryu Yong-Tae Kim Sun-Whe Kim Yong Bum Yoon Jin Hyeok Hwang Ho-Seong Han Sang Myung Woo Sang Jae Park | 2011 | Digestive and Liver Disease2011，，12： | 3 |
| 3 | Clinical outcomes of patients who experienced perforation associated with endoscopic retrograde cholangiopancreatography显示文摘 | Jaihwan Kim Sang Hyub Lee Woo Hyun Paik Byeong Jun Song Jin Hyeok Hwang Ji Kon Ryu Yong-Tae Kim Yong Bum Yoon | 2012 | Surgical Endoscopy2012，，11： | 2 |
| 4 | The optimal duration of preoperative biliary drainage for periampullary tumors that cause severe obstructive jaundice显示文摘 | Jun Hyuk Son Jaihwan Kim Sang Hyub Lee Jin-Hyeok Hwang Ji Kon Ryu Yong-Tae Kim Yong Bum Yoon Jin-Young Jang Sun-Whe Kim Jai Young Cho Yoo-Seok Yoon Ho-Seong Han Sang Myung Woo Woo Jin Lee Sang Jae Park | 2013 | The American Journal of Surgery2013，，1： | 1 |
| 5 | The optimal duration of preoperative biliary drainage for periampullary tumors that cause severe obstructive jaundice显示文摘 | Jun Hyuk Son Jaihwan Kim Sang Hyub Lee Jin-Hyeok Hwang Ji Kon Ryu Yong-Tae Kim Yong Bum Yoon Jin-Young Jang Sun-Whe Kim Jai Young Cho Yoo-Seok Yoon Ho-Seong Han Sang Myung Woo Woo Jin Lee Sang Jae Park | 2013 | The American Journal of Surgery2013，，1： | 1 |
| 6 | Increased incidence of indeterminate pancreatic cysts and changes of management pattern: Evidence from nationwide data显示文摘Background:Pancreatic cysts are common.However,most studies are based on data collected from individual centers.The present study aimed to evaluate the changes of management patterns for pancreatic cystic lesions(PCLs)by analyzing large epidemiologic data.Methods:Between January 2007 and December 2018,information regarding pancreatic cystic lesions was acquired from the nationwide Health Insurance Review and Assessment Service database in Korea.Results:The final number of patients with pancreatic cysts was 165277 among the total claims for reimbursement of 855983 associated with PCLs over 12 years.The total number of claims were increased from 19453 in 2007 to 155842 in 2018 and the prevalence increased from 0.04%to 0.23%.For 12 years,2874(1.7%)had pancreatic cancer and 8212(5.0%)underwent surgery,and 36 had surgery for twice(total 8248 pancreatectomy).After ruling out claims from the first 3 years of washout period,the incidence increased from 9891 to 24651 and the crude incidence rate of PCLs expanded from 19.96 per 100000 to 47.77 per 100000.Compared to specific neoplasm codes(D136 or D377),the use of pancreatic cyst code(K862)has been remarkably increased and the most common since 2010.The annual number of pancreatectomies increased from 518 to 861 between 2007 and 2012,and decreased to 596 until 2018.The percentage of pancreatic cancer in patients who received pancreatectomy increased from 5.6%in 2007 to 11.7%in 2018.Conclusions:The incidence of PCLs is rapidly increasing.Among PCLs,indeterminate cyst is increasing outstandingly.A trend of decreasing in the number of resections and increasing cancer rates among resected cysts may be attributed to the updated international guidelines. | Jaewoo Park Jinkyeong Park Yoon Suk Lee Kwangrok Jung In Ho Jung Jong-Chan Lee Jin-Hyeok Hwang Jaihwan Kim | 2023 | Hepatobiliary & Pancreatic Diseases International2023，22，3： | 0 |
| 7 | It is necessary to exam bottom and top slide smears of EUS-FNA for pancreatic cancer显示文摘Background: Despite many reports on the diagnostic yield of cytology from endoscopic ultrasound-guided fine-needle aspiration(EUS-FNA), inter-slide differences are unknown. This prospective study aimed to compare diagnostic yield and cellular characteristics of bottom slides(BS) and top slides(TS) from EUSFNA cytology performed without an on-site cytopathologist. Methods: In patients with suspected pancreatic cancer on previous imaging explorations, a single endoscopist performed EUS-FNA and obtained 2 sets of cytology slide(8 BS and 8 TS), 1 cellblock slide, and 1 biopsy slide. Both slide sets were randomly assigned. A cytopathologist with more than 10 years of expertise in pancreatic cytopathology blindly inspected and compared two slide sets. Results: In total, 73 specimens [42 head(57.5%), 16 body(21.9%), and 15 tail(20.5%)] were acquired for final analysis. Seventy-one cases were finally diagnosed with pancreatic cancer. The sensitivity and specificity of BS were 80.3% and 100.0%; and of TS 78.9% and 100.0%, respectively. In analyzing inter-slide difference, 66 cases(90.4%) showed consistent results between BS and TS. However, seven(9.6%) were positive only in one slide sets(4 BS and 3 TS). The proportions of specimens more than moderate and high cellularity were 75.3% and 60.3% in both slide sets( P > 0.99), and the proportion of artifact-free sets were 50.7%, and 52.1% for the BS and TS, respectively( P = 0.869). Conclusions: Although BS and TS exhibited highly consistent diagnostic yields in cytologic smears from EUS-FNA, the proportion of inter-slide discordance is clinically considerable. Both slide sets need to be examined if there is no on-site cytopathologist. | Jong-chanb Lee Haeryoung Kim Hyoung Woo Kim Jongchan Lee Kyu-hyun Paik Jingu Kang Jin-Hyeok Hwang Jaihwan Kim | 2018 | Hepatobiliary & Pancreatic Diseases International2018，17，6： | 0 |
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