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| 1 | Portal hypertension: Imaging of portosystemic collateral pathways and associated image-guided therapy显示文摘Portal hypertension is a common clinical syndrome, defined by a pathologic increase in the portal venous pressure. Increased resistance to portal blood flow, the primary factor in the pathophysiology of portal hypertension, is in part due to morphological changes occurring in chronic liver diseases. This results in rerouting of blood flow away from the liver through collateral pathways to low-pressure systemic veins. Through a variety of computed tomographic, sonographic, magnetic resonance imaging and angiographic examples, this article discusses the appearances and prevalence of both common and less common portosystemic collateral channels in the thorax and abdomen. A brief overview of established interventional radiologic techniques for treatment of portal hypertension will also be provided. Awareness of the various imaging manifestations of portal hypertension can be helpful for assessing overall prognosis and planning proper management. | Murad Feroz Bandali Anirudh Mirakhur Edward Wolfgang Lee Mollie Clarke Ferris David James Sadler Robin Ritchie Gray Jason Kam Wong | 2017 | World Journal of Gastroenterology2017,23,10: | 14 |
| 2 | Elucidation of the ‘Honeycrisp’ pedigree through haplotype analysis with a multi-family integrated SNP linkage map and a large apple (Malus×domestica) pedigree-connected SNP data set显示文摘The apple(Malus×domestica)cultivar Honeycrisp has become important economically and as a breeding parent.An earlier study with SSR markers indicated the original recorded pedigree of‘Honeycrisp’was incorrect and‘Keepsake’was identified as one putative parent,the other being unknown.The objective of this study was to verify‘Keepsake’as a parent and identify and genetically describe the unknown parent and its grandparents.A multi-family based dense and high-quality integrated SNP map was created using the apple 8 K Illumina Infinium SNP array.This map was used alongside a large pedigree-connected data set from the RosBREED project to build extended SNP haplotypes and to identify pedigree relationships.‘Keepsake’was verified as one parent of‘Honeycrisp’and‘Duchess of Oldenburg’and‘Golden Delicious’were identified as grandparents through the unknown parent.Following this finding,siblings of‘Honeycrisp’were identified using the SNP data.Breeding records from several of these siblings suggested that the previously unreported parent is a University of Minnesota selection,MN1627.This selection is no longer available,but now is genetically described through imputed SNP haplotypes.We also present the mosaic grandparental composition of‘Honeycrisp’for each of its 17 chromosome pairs.This new pedigree and genetic information will be useful in future pedigree-based genetic studies to connect‘Honeycrisp’with other cultivars used widely in apple breeding programs.The created SNP linkage map will benefit future research using the data from the Illumina apple 8 and 20 K and Affymetrix 480 K SNP arrays. | Nicholas P Howard Eric van de Weg David S Bedford Cameron P Peace Stijn Vanderzande Matthew D Clark Soon Li Teh Lichun Cai James J Luby | 2017 | Horticulture Research2017,4,1: | 9 |
| 3 | The First Stegosaur (Dinosauria, Ornithischia) from the Upper Jurassic Shishugou Formation of Xinjiang, China显示文摘新 stegosaur 种, Jiangjunosaurus junggarensis,情报。et sp。nov,基于在 Junggar 盆从 ShishugouFormation 的上面的侏罗记上面的节收集的一个标本被树立, Xinjiang,中国。它从 Jurassicof Xinjiang 代表第一 stegosaur 并且在 Shishugou 形成增加恐龙动物志的差异。新类被对称、按比例宽的牙齿王冠描绘,亚 rectangular 在侧面的看法看见的轴的神经脊骨,和 cervicalcentra 的侧面的表面上的大洞。初步的特性分析建议那这新税在上更多比中间的侏罗记 stegosaur Huayangosaurus 被导出但是比大多数另外的已知的 stegosaur 种类更原始。 | JIA Chengkai Catherine A. FOSTER XU Xing James M. CLARK | 2007 | Acta Geologica Sinica(English Edition)2007,81,3: | 6 |
| 4 | Implications of Recent Clinical Trials for the National Cholesterol Education Program Adult Treatment Panel III Guidelines显示文摘 | Scott M. Grundy James I. Cleeman C. Noel Bairey Merz H. Bryan Brewer Luther T. Clark Donald B. Hunninghake Richard C. Pasternak Sidney C. Smith Neil J. Stone | 2004 | Circulation: Journal of the American Heart Association2004,,2: | 6 |
| 5 | Natural orifice translumenal endoscopic surgery: critical appraisal of applications in clinical practice显示文摘 | Mikael H. Sodergren James Clark Thanos Athanasiou Julian Teare Guang-Zhong Yang Ara Darzi | 2009 | Surgical Endoscopy2009,,4: | 4 |
| 6 | Perinatal Listeria monocytogenes susceptibility despite preconceptual priming and maintenance of pathogen-specific CD8^+ T cells during pregnancy显示文摘Listeria monocytogenes (Lm ) 为发展中的胎儿在怀孕和疾病的后果期间是有为全身的母亲的感染的唯一的倾向的一个细胞内部的细菌。给与出生前的 Lm 感染联系的高死亡,为在怀孕的极其脆弱的经期期间扩充保护的免疫的策略着急地被需要。此处,保护由在对随后的剧毒的 Lm 出生前的感染的怀孕被评估以前,管理的稀释 Lm 交谈了。因为显著地更多的细菌从母亲的纸巾被恢复,我们证明对在非怀孕的老鼠的第二等的 Lm 感染的保护严厉地在 allogeneic 怀孕期间被节制,尽管有病原体特定的 CD8 + T 房间的数字、功能的保藏。更重要地,因为各在怀孕和天真的怀孕控制以前与稀释 Lm 接种的老鼠在怀孕期间在 Lm 感染以后从单个 concepti 显示出近完全的胎儿的再吞和病原体恢复, preconceptual priming 不在 utero 侵略或胎儿的消耗量免于。显著地,对有在 allogeneic 怀孕的 preconceptual priming 的出生前的 Lm 感染的保护的缺乏在 syngeneic 怀孕期间被恢复。因此,母亲胎儿的抗原不和在出生前的 Lm 感染以后对胎儿的复杂并发症支配 preconceptual 种痘的低效率,尽管有病原体特定的 CD8 + T 房间的数字、功能的保藏。 | Dayna R Clark Vandana Chaturvedi Jeremy M Kinder Tony T Jiang Lijun Xin James M Ertelt Sing Sing Way | 2014 | Cellular & Molecular Immunology2014,11,6: | 3 |
| 7 | The Effects of Pedicle Screw Fit: An In Vitro Study显示文摘 | Anna G U Brantley Jack K. Mayfield James B. Koeneman Kathleen R. Clark | 1994 | Spine1994,,15: | 2 |
| 8 | A next-generation marker genotyping platform(AmpSeq)in heterozygous crops:a case study for marker-assisted selection in grapevine显示文摘Marker-assisted selection(MAS)is often employed in crop breeding programs to accelerate and enhance cultivar development,via selection during the juvenile phase and parental selection prior to crossing.Next-generation sequencing and its derivative technologies have been used for genome-wide molecular marker discovery.To bridge the gap between marker development and MAS implementation,this study developed a novel practical strategy with a semi-automated pipeline that incorporates trait-associated single nucleotide polymorphism marker discovery,low-cost genotyping through amplicon sequencing(AmpSeq)and decision making.The results document the development of a MAS package derived from genotyping-by-sequencing using three traits(flower sex,disease resistance and acylated anthocyanins)in grapevine breeding.The vast majority of sequence reads(⩾99%)were from the targeted regions.Across 380 individuals and up to 31 amplicons sequenced in each lane of MiSeq data,most amplicons(83 to 87%)had<10%missing data,and read depth had a median of 220–244×.Several strengths of the AmpSeq platform that make this approach of broad interest in diverse crop species include accuracy,flexibility,speed,high-throughput,low-cost and easily automated analysis. | Shanshan Yang Jonathan Fresnedo-Ramíre Minghui Wang Linda Cote Peter Schweitzer Paola Barba Elizabeth M Takacs Matthew Clark James Luby David C Manns Gavin Sacks Anna Katharine Mansfield Jason Londo Anne Fennell David Gadoury Bruce Reisch Lance Cadle-Davidson Qi Sun | 2016 | Horticulture Research2016,3,1: | 2 |
| 9 | Acute care needs in an Indian emergency department: A retrospective analysis显示文摘BACKGROUND: Emergencies such as road traffic accidents(RTAs), acute myocardial infarction(AMI) and cerebrovascular accident(CVA) are the most common causes of death and disability in India. Robust emergency medicine(EM) services and proper education on acute care are necessary. In order to inform curriculum design for training programs, and to improve the quality of EM care in India, a better understanding of patient epidemiology and case burden presenting to the emergency department(ED) is needed.METHODS: This study is a retrospective chart review of cases presenting to the ED at Kerala Institute of Medical Sciences(KIMS), a private hospital in Trivandrum, Kerala, India, from November 1, 2011 to April 21, 2012 and from July 1, 2013 to December 21, 2013. De-identified charts were systematically sampled and reviewed.RESULTS: A total of 1 196 ED patient charts were analyzed. Of these patients, 55.35%(n=662) were male and 44.7%(n=534) were female. The majority(67.14%, n=803) were adults, while only 3.85%(n=46) were infants. The most common chief complaints were fever(21.5%, n=257), renal colic(7.3%, n=87), and dyspnea(6.9%, n=82). The most common ED diagnoses were gastrointestinal(15.5%, n=185), pulmonary(12.3%, n=147), tropical(11.1%, n=133), infectious disease and sepsis(9.9%, n=118), and trauma(8.4%, n=101).CONCLUSION: The patient demographics, diagnoses, and distribution of resources identifi ed by this study can help guide and shape Indian EM training programs and faculty development to more accurately refl ect the burden of acute disease in India. | Elizabeth G. Clark Jessica Watson Allison Leemann Alan H. Breaud Frank G. Feeley III James Wolff Tamorish Kole Gabrielle A. Jacquet | 2016 | World Journal of Emergency Medicine2016,7,3: | 2 |
| 10 | Activity of Crizotinib (PF02341066), a Dual Mesenchymal-Epithelial Transition (MET) and Anaplastic Lymphoma Kinase (ALK) Inhibitor, in a Non-small Cell Lung Cancer Patient with De Novo MET Amplification显示文摘 | Sai-Hong Ignatius Ou Eunice L. Kwak Christina Siwak-Tapp Joni Dy Kristin Bergethon Jeffrey W. Clark D. Ross Camidge Benjamin J. Solomon Robert G. Maki Yung-Jue Bang Dong-Wan Kim James Christensen Weiwei Tan Keith D. Wilner Ravi Salgia A. John Iafrate | 2011 | Journal of Thoracic Oncology2011,,5: | 2 |
| 11 | Hierarchical geometric models for visible surface algorithms显示文摘 | James H. Clark | 1976 | Communications of the ACM1976,,10: | 2 |
| 12 | Plant species identification using digital morphometrics: A review显示文摘 | James S. Cope David Corney Jonathan Y. Clark Paolo Remagnino Paul Wilkin | 2012 | Expert Systems With Applications2012,,8: | 2 |
| 13 | Prognostic Significance of Myocardial Fibrosis in Hypertrophic Cardiomyopathy显示文摘 | Rory O’Hanlon Agata Grasso Michael Roughton James C. Moon Susan Clark Ricardo Wage Jessica Webb Meghana Kulkarni Dana Dawson Leena Sulaibeekh Badri Chandrasekaran Chiara Bucciarelli-Ducci Ferdinando Pasquale Martin R. Cowie William J. McKenna Mary N. Shep | 2010 | Journal of the American College of Cardiology2010,,11: | 2 |
| 14 | Complete genomes of two clinical Staphylococcus aureus strains:evidence for the rapid evolution of virulence and drug resistance显示文摘 | Holden MT Feil EJ Lindsay JA Peacock SJ Day NP Enright MC Foster TJ Moore CE Hurst L Atkin R Barron A Bason N Bentley SD Chillingworth C Chillingworth T Churcher C Clark L Corton C Cronin A Doggett J Dowd L Feltwell T Hance Z Harris B Hauser H Holroyd S Jagels K James KD Lennard N Line A Mayes R Moule S Mungall K Ormond D Quail MA Rabbinowitsch E Rutherford K Sanders M Sharp S Simmonds M Stevens K Whitehead S Barrell BG Spratt BG Parkhill J | 2004 | Proc Natl Acad Sci USA2004,101,26: | 1 |
| 15 | Intrauterine growth restriction increases morbidity and mortality among premature neonates显示文摘 | Thomas J. Garite Reese Clark James A. Thorp | 2004 | American Journal of Obstetrics and Gynecology2004,,2: | 1 |
| 16 | Outcomes of the Arterial Switch Operation for Transposition of the Great Arteries: 25 Years of Experience显示文摘 | Tyson A. Fricke Yves d’Udekem Malcolm Richardson Clarke Thuys Mithilesh Dronavalli James M. Ramsay Gavin Wheaton Leeanne E. Grigg Christian P. Brizard Igor E. Konstantinov | 2012 | The Annals of Thoracic Surgery2012,,1: | 1 |
| 17 | Preparation of a novel silica-supported palladium catalyst and its use in the Heck reaction 显示文摘 | James H Clark Duncan J Macquarrie Egid B Mubofu | 2000 | Green Chemistry2000,2,2: | 1 |
| 18 | Relative sensi- tivity of six estuarine fishes to carbophenothi on chloropyrifosand fenvalerate 显示文摘 | CLARK J R JAMES M PATRICK J | 1985 | Ecotoxicol Environ Saf1985,10,: | 1 |
| 19 | The effect of defects on the performance of post-buckled CFRP stringer-stiffened panels显示文摘 | Emile Greenhalgh Charlotte Meeks Andrew Clarke James Thatcher | 2003 | Composites Part A2003,,7: | 1 |
| 20 | Effects of imaging system and exposure on accurate detection of the second mesio-buccal canal in maxillary molar teeth显示文摘 | Ramya Ramamurthy James P. Scheetz Stephen J. Clark Allan G. Farman | 2006 | Oral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontology2006,,6: | 1 |