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| 1 | Rattle-Type Silica Colloidal Particles Prepared by a Surface- Protected Etching Process显示文摘This paper explores the capability of the“surface-protected etching”process for the creation of rattle-type SiO_(2)@void@SiO_(2) colloidal structures featuring a mesoporous silica shell and a mesoporous movable silica core.The surface-protected etching process involves stabilization of the particle surface using a polymer ligand,and then selective etching of the interior to form hollow structures.In this paper,this strategy has been extended to the formation of rattle-like structures by etching SiO_(2)@SiO_(2) core shell particles which are synthesized by a two-step sol gel process.The key is to introduce a protecting polymer of polyvinylpyrrolidone(PVP)to the surface of both core and shell in order to tailor their relative stability against chemical etching.Upon reacting with NaOH,the outer layer silica becomes a hollow shell as only the surface layer is protected by PVP and the interior is removed,while the core remains its original size thanks to the protection of PVP on its surface.This process can be carried out at room temperature without the need of additional templates or complicated heterogeneous coating procedures.The etching process also results in the rattle-type colloids having mesoscale pores with two distinct average sizes.In our demonstration of a model drug delivery process,such mesoporous structures show an interesting two-step elution profile which is believed to be related to the unique porous rattle structures. | Qiao Zhang Jianping Ge James Goebl Yongxing Hu Zhenda Lu Yadong Yin | 2009 | Nano Research2009，2，7： | 18 |
| 2 | Single-cell RNA-seq reveals the diversity of trophoblast subtypes and patterns of differentiation in the human placenta显示文摘胎盘为成功的怀孕和胎儿和怀孕女人的健康是关键的。然而,人的 trophoblast 系怎么被调整,包括胎盘的房间的分类,子类型糟糕被理解。这里,我们在排序的胎盘的房间上执行了定序的单个房间的 RNA (RNA-seq ) 从第一三个月并且秒三个月人胎盘。已知的 cytotrophoblast 房间(CTB ) 的房间的新子类型, extravillous trophoblast 房间(EVT ) , Hofbauer 房间,和间充质的 stromal 房间被识别, cell-type-specific 基因签名被定义。机能上地,这研究揭示了人的胎盘的许多以前未知的功能。尤其是, 102 多肽荷尔蒙基因被发现被胎盘的房间的各种各样的子类型表示,它在调整母亲的生理学的胎儿的生长和改编到怀孕建议建筑群和这些荷尔蒙的重要角色。这些结果在单个房间的分辨率记录人的胎盘的 trophoblast 区别并且因此在怀孕的早阶段期间推进我们人的胎座式的理解。 | Yawei Liu Xiaoying Fan Rui Wang Xiaoyin Lu Yan-Li Dang Huiying Wang Hai-Yan Lin Cheng Zhu Hao Ge James C. Cross Hongmei Wang | 2018 | Cell Research2018，28，8： | 15 |
| 3 | Exploring in vitro roles of siRNA in cardiovascular disease显示文摘RNA 干扰( RNAi )是通过 搁浅whichdouble 的 RNA 沉默的适应防卫机制在顺序特定的 manner.It 的血缘的基因被采用了在功能的 genomics 的一个强大的工具学习的 widelyas ,目标确认并且治疗学 productdevelopment.Similarly ,到涉及心血管的疾病的 引起thedisease 基因的 silencing 的小介入的 RNA ( siRNA )的申请使大 progress.In 成为了 thisoverview 。 | Yu TANG Yu-zhi GE James Q YIN | 2007 | Acta Pharmacologica Sinica2007，28，1： | 3 |
| 4 | Hyperspectral reflectance-based phenotyping for quantitative genetics in crops: Progress and challenges显示文摘Many biochemical and physiological properties of plants that are of interest to breeders and geneticists have extremely low throughput and/or can only be measured destructively.This has limited the use of information on natural variation in nutrient and metabolite abundance,as well as photosynthetic capacity in quantitative genetic contexts where it is necessary to collect data from hundreds or thousands of plants.A number of recent studies have demonstrated the potential to estimate many of these traits from hyperspectral reflectance data,primarily in ecophysiological contexts.Here,we summarize recent advances in the use of hyperspectral reflectance data for plant phenotyping,and discuss both the potential benefits and remaining challenges to its application in plant genetics contexts.The performances of previously published models in estimating six traits fromhyperspectral reflectance data in maizewere evaluated on newsample datasets,and the resulting predicted trait values shown to be heritable(e.g.,explained by genetic factors)were estimated.The adoption of hyperspectral reflectance-based phenotyping beyond its current uses may accelerate the study of genes controlling natural variation in biochemical and physiological traits. | Marcin Grzybowski Nuwan K.Wijewardane Abbas Atefi Yufeng Ge James C.Schnable | 2021 | Plant Communications2021，2，4： | 2 |
| 5 | Assay of cyclooxygenase-1 and 2 in human monocytes 显示文摘 | Demasi M Canghey GE James MJ | 2000 | Inflamm Res2000，49，12： | 1 |
| 6 | High frequency of the 844ins68 cystathionine-beta-synthase gene variant in Down syndrome children with acute myeloid leukemia 显示文摘 | Ge Y Jensen T James SJ | 2002 | Leukemia2002，16，： | 1 |
| 7 | Transcatheter Aortic-Valve Replacement with a Self-Expanding Prosthesis显示文摘 | David H. Adams Jeffrey J. Popma Michael J. Reardon Steven J. Yakubov Joseph S. Coselli G. Michael Deeb Thomas G. Gleason Maurice Buchbinder James Hermiller Neal S. Kleiman Stan Chetcuti John Heiser William Merhi George Zorn Peter Tadros Newell Robinson Ge | 2014 | The New England Journal of Medicine2014，，19： | 1 |
| 8 | Assay of cyclooxygenase-1 and 2 in human monocytes显示文摘 | DEMASI M CAUGHEY GE JAMES MJ | 2000 | Inflamm Res2000，49，12： | 1 |
| 9 | How cells absorb glucose显示文摘 | Lienhard GE Slot JW James DE | | 0，，： | 1 |
| 10 | Generation of waves in Boussinesq models using a source function method显示文摘 | Ge Wei James T. Kirby Amar Sinha | 1999 | Coastal Engineering1999，，4： | 1 |
| 11 | The Safety of Intracoronary Ultrasound: A Multicenter Survey of 2207 Examinations显示文摘 | Dirk Hausmann Raimund Erbel Marie-J. Alibelli-Chemarin Wolfgang Boksch Eugene Caracciolo Joel M. Cohn Stephen C. Culp Werner G. Daniel Ivan De Scheerder Carlo DiMario James J. Ferguson Peter J. Fitzgerald Guy Friedrich Junbo Ge Gunther Gorge Peter Hanrath | 1995 | Circulation1995，，3： | 1 |
| 12 | Air pollution in Boston bars before and after a smoking ban显示文摘 | James L Repace James N Hyde Doug Brtm ge | 2006 | BMC public health2006，6，： | 1 |
| 13 | Selec-tion of Cell Source for Ligament Tissue Engineering 显示文摘 | Zigang Ge James Cho Hong Goh Eng Hin Lee | 2005 | Cell Transplantation2005，14，： | 1 |
| 14 | Prolonged insula activation during perception of aftertaste显示文摘 | James GA Li XB DuBois GE Zhou L Hu XP | | 0，，： | 1 |
| 15 | BRCA1 mRNA expression levels predict for overall survival in ovarian cancer after chemotherapy显示文摘 | Quinn JE James CR Stewart GE | 2007 | Clin Cancer Res2007，13，24： | 1 |
| 16 | BRCA1 mRNA expression levels predict for overall survival in ovarian cancer after chemotherapy 显示文摘 | Quinn JE James CR Stewart GE | 2007 | Clin Cancer Res2007，13，24： | 1 |
| 17 | Generation of waves in Boussinesq models using a source function method显示文摘 | Ge Wei James T K Amar S | 1999 | Coastal Engineering1999，36，： | 1 |
| 18 | Experimental investigation of link tension and roller-sprocket impact in roller chain drives显示文摘 | James C Con well GE Johnson | 1995 | Mechanism and Machine Theory1995，4，31： | 1 |
| 19 | In the absence of aminopeptidase ERAAP, MHC class I molecules present many unstable and highly immunogenic peptides 显示文摘 | Hammer GE Gonzalez F James E | 2007 | Nat Immunol2007，8，1： | 1 |
| 20 | BRCA1 mRNA et ex- pression levels predict for overall survival in ovarian cancer af- ter chemotherapy显示文摘 | Quinn JE James CR Stewart GE al | 2007 | Clin Cancer Res2007，7413，： | 1 |
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