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8篇 您的检索式：作者名="James Helm"

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		题名	作者	年代	出处	被引量
	1	MicroRNAs in pancreatic ductal adenocarcinoma显示文摘Ductal adenocarcinoma of the pancreas is a lethal cancer for which the only chance of long-term survival belongs to the patient with localized disease in whom a potentially curative resection can be done. Therefore, biomarkers for early detection and new therapeutic strategies are urgently needed. miRNAs are a recently discovered class of small endogenous non-coding RNAs of about 22 nucleotides that have gained attention for their role in downregulation of mRNA expression at the post-transcriptional level. miRNAs regulate proteins involved in critical cellular processes such as differentiation, proliferation, and apoptosis. Evidence suggests that deregulated miRNA expression is involved in carcinogenesis at many sites, including the pancreas. Aberrant expression of miRNAs may upregulate the expression of oncogenes or downregulate the expression of tumor suppressor genes, as well as play a role in other mechanisms of carcinogenesis. The purpose of this review is to summarize our knowledge of deregulated miRNA expression in pancreatic cancer and discuss the implication for potential translation of this knowledge into clinical practice.	Jong Y Park James Helm Domenico Coppola Donghwa Kim Mokenge Malafa Seung Joon Kim	2011	World Journal of Gastroenterology2011，17，7：	7
	2	PHYTIC ACID显示文摘	Lori Oatway Thava Vasanthan James H Helm	2001	Food Reviews International2001，17，4：	1
	3	Dose–response of cyclosporin A in attenuating traumatic axonal injury in rat显示文摘	David O. Okonkwo David E. Melon Anthony J. Pellicane Leman K. Mutlu David G. Rubin James R. Stone Gregory A. Helm	2003	NeuroReport2003，，3：	1
	4	PHYTIC ACID显示文摘	Lori Oatway Thava Vasanthan James H Helm	2001	Food Reviews International2001，17，4：	1
	5	Impaired axonal transport and altered axolemmal permeability occur in distinct populations of damaged axons following traumatic brain injury显示文摘	James R. Stone David O. Okonkwo Alfa O. Dialo David G. Rubin Leman K. Mutlu John T. Povlishock Gregory A. Helm	2004	Experimental Neurology2004，，1：	1
	6	HIV Testing Frequency Among Men Who Have Sex With Men Attending Sexually Transmitted Disease Clinics: Implications for HIV Prevention and Surveillance显示文摘	Donna J Helms Hillard S Weinstock Kristen C Mahle Kyle T Bernstein Bruce W Furness Charlotte K Kent Cornelis A Rietmeijer Akbar M Shahkolahi James P Hughes Matthew R Golden	2009	JAIDS Journal of Acquired Immune Deficiency Syndromes2009，，3：	1
	7	Patterns and regulation of mycorrhizal plant and fungal diversity显示文摘	Edith B. Allen Michael F. Allen Dot J. Helm James M. Trappe Randy Molina Emmanuel Rincon	1995	Plant and Soil1995，，1：	1
	8	A putative RUNX1 binding site variant between SLC9A3R1 and NAT9 is associated with susceptibility to psoriasis显示文摘	Cynthia Helms Li Can James G Krueger	2003	Nature genetics2003，35，4：	1

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