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| 1 | Borderline Resectable Pancreatic Cancer: Definitions, Management, and Role of Preoperative Therapy显示文摘 | Gauri R. Varadhachary MD Eric P. Tamm MD James L. Abbruzzese MD Henry Q. Xiong MD Christopher H. Crane MD Huamin Wang MD Jeffrey E. Lee MD Peter W. T. Pisters MD Douglas B. Evans MD Robert A. Wolff MD | 2006 | Annals of Surgical Oncology2006，，8： | 4 |
| 2 | The Value of Serum CA 19-9 in Predicting Cholangiocarcinomas in Patients with Primary Sclerosing Cholangitis显示文摘 | Cynthia Levy MD James Lymp PhD Paul Angulo MD Gregory J. Gores MD Nicholas Larusso MD Keith D. Lindor | 2005 | Digestive Diseases and Sciences2005，，9： | 3 |
| 3 | Magnitude of modulation of gene expression in aneuploid maize depends on the extent of genomic imbalance显示文摘Aneuploidy has profound effects on an organism,typically more so than polyploidy,and the basis of this contrast is not fully understood.A dosage series of the maize long arm of chromosome 1(1L)was used to compa re relative global gene expression in diffe rent types and degrees of aneuploidy to gain insights into how the magnitude of genomic imbalance as well as hypoploidy affects global gene expression.While previously available methods require a selective examination of specific genes,RNA sequencing provides a whole-genome view of gene expression in aneuploids.Most studies of global aneuploidy effects have concentrated on individual types of aneuploids because multiple dose aneuploidies of the same genomic region are difficult to produce in most model genetic organisms.The genetic toolkit of maize allows the examination of multiple ploidies and 1-4 doses of chromosome arms.Thus,a detailed examination of expression changes both on the varied chromosome arms and elsewhere in the genome is possible,in both hypoploids and hyperploids,compared with euploid controls.Previous studies observed the inverse trans effect,in which genes not varied in DNA dosage were expressed in a negative relationship to the varied chromosomal region.This response was also the major type of changes found globally in this study.Many genes varied in dosage showed proportional expression changes,though some were seen to be partly or fully dosage compensated.It was also found that the effects of aneuploidy were progressive,with more severe aneuploids producing effects of greater magnitude. | Adam F·Johnson Jie Hou Hua Yang Xiaowen Shi Chen Chen Md Soliman Islam Tieming Ji Jianlin Cheng James A·Birchler | 2020 | Journal of Genetics and Genomics2020，47，2： | 3 |
| 4 | Intraductal Papillary Mucinous Neoplasms of the Pancreas: Effect of Invasion and Pancreatic Margin Status on Recurrence and Survival显示文摘 | Chandrajit P. Raut MD Karen R. Cleary MD Gregg A. Staerkel MD James L. Abbruzzese MD Robert A. Wolff MD Jeffrey H. Lee MD Jean-Nicolas Vauthey MD Jeffrey E. Lee MD Peter W. T. Pisters MD Douglas B. Evans MD | 2006 | Annals of Surgical Oncology2006，，4： | 3 |
| 5 | Natural history of alcoholic hepatitis显示文摘 | Mark W. Lischner MD James F. Alexander MD John T. Galambos MD | 1971 | The American Journal of Digestive Diseases1971，，6： | 2 |
| 6 | Survival After Resection of Ampullary Carcinoma: A National Population-Based Study显示文摘 | Jessica B. O'Connell MD Melinda A. Maggard MD Jesse Manunga MD James S. Tomlinson MD Howard A. Reber MD Clifford Y. Ko MD O. Joe Hines MD | 2008 | Annals of Surgical Oncology2008，，7： | 2 |
| 7 | Positive Peritoneal Cytology in Patients with Gastric Cancer: Natural History and Outcome of 291 Patients显示文摘 | James J. Mezhir MD Manish A. Shah MD Lindsay M. Jacks MS Murray F. Brennan MD Daniel G. Coit MD Vivian E. Strong MD | 2010 | Annals of Surgical Oncology2010，，12： | 2 |
| 8 | Acidosis, oxygen, and interference with mitochondrial permeability transition pore formation in the early minutes of reperfusion are critical to postconditioning’s success显示文摘 | Michael V. Cohen MD Xi-Ming Yang James M. Downey | 2008 | Basic Research in Cardiology2008，，5： | 2 |
| 9 | Cytoreductive Surgery and Intraperitoneal Hyperthermic Chemotherapy With Mitomycin C for Peritoneal Carcinomatosis from Nonappendiceal Colorectal Carcinoma显示文摘 | Perry Shen MD Jason Hawksworth MD James Lovato PhD Brian W. Loggie MD Kim R. Geisinger MD Ronald A. Fleming PharmD Edward A. Levine MD | 2004 | Annals of Surgical Oncology2004，，2： | 2 |
| 10 | Population-Based Study of Islet Cell Carcinoma显示文摘 | James C. Yao MD Milton P. Eisner PhD Colleen Leary MPH Cecile Dagohoy MD Alexandria Phan MD Asif Rashid MD Manal Hassan MD PhD MPH Douglas B. Evans MD | 2007 | Annals of Surgical Oncology2007，，12： | 2 |
| 11 | 2004年加拿大预防血透病人医院血流感染的成本-效益分析显示文摘目的:血液透析相关的血流感染是一个严重的公共健康问题,因为加拿大的血液透析病人从1996年到2005翻了一番。本研究目的在于确定加拿大医院血流感染的成本,估算在综合性医院中建立感染控制项目的成本,并进行成本-效益分析。材料与方法:用加拿大医院感染监测项目的数据来估算医院血流感染的发生率。用加拿大健康信息所数据来估算2004年加拿大平均一次血流感染住院的额外成本。建立和维护一个感染控制项目的成本用美国疾病预防与控制中心1985年的成本换算为2004年的加拿大成本来估算。假设感染控制项目能降低医院血流感染病例的20%~30%。结果:2004年的加拿大15278名血液透析病人中估计共有2524人发生血流感染。全年用于治疗血流感染的成本估计为4901万加元。医院血流感染预防和人力资源的总投资成本为815万加元。建立医院感染控制项目后能带来1452万加元的医疗成本节约。效益成本比在1.0:1到1.8:1之间。结论:本研究提供的证据表明,如果医院感染控制项目能降低20%~30%的感染,该项目的经济效益将远超过增加的成本。医院感染控制项目将带来双重效益:节约货币成本的同时改善医疗质量。 | Zhiyong Hong MD DrPH Jun Wu PhD Crystal O'Leary BHSc Clem Tisdell James Gomes Shi-Wu Wen Howard Njoo 李洪超 | 2010 | 中国药物经济学2010，，1： | 2 |
| 12 | Factors that influence induction of gastroesophageal reflux in normal human subjects显示文摘 | John Dent MD Wylie J. Dodds MD Walter J. Hogan MD James Toouli MD | 1988 | Digestive Diseases and Sciences1988，，3： | 2 |
| 13 | Internel survey of Foley catheter practices and knowledge among Minnesota nurses显示文摘 | Dimitri MD Michael AK James RJ | 2010 | American Journal of Infection Control2010，38，1： | 1 |
| 14 | Can a simulated critical care encounter accelerate basic science learning among preclinical medical students? A Pilot Study显示文摘 | James A Gordon MD | 2006 | Simulation in Healthcare2006，，1： | 1 |
| 15 | Repair of palatal bone de-fects using osteogenically differentiated fat-derived stem cells 显示文摘 | Mejandro C J James A Lee MD | 2006 | J Plastic Reconstruct Sur2006，117，3： | 1 |
| 16 | Twelve steps to op- timal management of HELLP syndrome显示文摘 | Magann MD Everett F James N | 1999 | Clin Obstet Gy- necol1999，42，3： | 1 |
| 17 | Aortic dissection显示文摘 | James I. Fann MD D. Craig Miller MD | 1995 | Annals of Vascular Surgery1995，，3： | 1 |
| 18 | Procedural outcomes and long-term survival among patients undergoing percutaneous coronary intervention of a chronic total occlusion in native coronary arteries:a 20-year experience显示文摘 | James A Suero MD Steven P | 2001 | Indian Heart J2001，53，6： | 1 |
| 19 | Benign blood vascular tumors of the mediastinum显示文摘 | Gene JM Reginald G | 1978 | Radiology1978，126，3： | 1 |
| 20 | A computer-assisted technique for 24-hour esophageal monitoring显示文摘 | Rebecca B. Troxell PA-C Sarah R. Kohn BA Dr. James E. Gray MD Richard W. Welch MD Edward D. Harloe BS Raj K. Goyal MD | 1982 | Digestive Diseases and Sciences1982，，12： | 1 |
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