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22篇 您的检索式:作者名="Jammula"
    题名 作者 年代 出处 被引量
1Improvement in the dissolution rate and tableting properties of cefuroxime axetil by melt-granulated dispersion and surface adsorption显示文摘A combination of melt-granulated dispersion and surface adsorption techniques was used to enhance the dissolution and tableting properties of cefuroxime axetil(CA).Gelucire 50/13 was used as the melt-dispersion carrier and Sylysia 350 was used to adsorb the melt dispersion.Solubility studies showed an 8-fold increase in solubility at a ratio of 1:1.5 for CA:Gelucire 50/13.The minimum quantity of Sylysia 350 required to achieve the desired flowability and compressibility was 0.5 parts of Sylysia 350 per unit of Gelucire 50/13.Phase solubility studies showed negative ΔG_(tr)^(0) values for Gelucire 50/13 at various concentrations(2-10%,vv/v),indicating the spontaneous nature of solubilization.FT-IR and DSC spectra exhibited drug-excipient compatibility.Molecular modeling by a computational method employing energy minimization revealed entrapment of CA in Gelucire 50/13.The total potential energy of CA(70.562 keal/mol)was reduced to 33.578 keal/mol after solid dispersion with Gelucire 50/13.P-XRD studies indicated that the presence of Sylysia 350 is less likely to promote the reversion of the amorphous CA to a crystalline state.In vitro dissolution studies demonstrated an improved dissolution rate,and drug release at 15 min(Q_(15min))exhibited a 15-fold improvement.The rapidly dissolving CA tablets showed improved dissolution with improved tableting properties.Jammula Sruti Chinam Niranjan Patra Suryakanta Swain Kanhu Charan Panigrahi Allupati Premananda Patro Sarwar Beg Subas Chandra Dinda Muddana Eswara Bhanoji Rao 2013Acta Pharmaceutica Sinica B2013,3,2:2
2Aberrant angiogenesis:The gateway to diabetic complications显示文摘Kota SK Meher LK Jammula S 2012Indian J Endocrinol Metab2012,16,6:1
3Genetics of type 2 diabetes mellitus and other specific types of diabetes; its role in treatment modalities显示文摘Kota SK Meher LK Jammula S 2012Diabetes2012,6,1:1
41164 Adherence to Prog-rammatic Annual Fecal Occult Blood Test(gFOBt)Versus Scre-ening Colonoscopy in African Americans Compared to Whites With Equal Access and Navigation:Observations From National Colonoscopy Study(NCS)显示文摘Jammula A Winawer SJ Mills GM 0,,05:1
5Hypertriglyceridemia-inducedrecurrent acute pancreatitis: A case-based review显示文摘Kota S K Kota S K Jammula S 2012Indian J EndocrinolMetab2012,16,1:1
6Necrobiosis lipoidica diabeticorum:A case-based review of literature 显示文摘Kota SK Jammula S Kota SK 2012Indian Journal of Endocrinology and Metabolism2012,16,4:1
7Coexistence of pheochromocytoma with abdominal aortic aneurysm: An untold association显示文摘S Kota S Kota L Meher S Jammula S Mohapatra K Modi 2013Annals of Medical and Health Sciences Research2013,,2:1
8Renin-angiotensin system activity in vitamin D deficient, obese individuals with hyperten- sion: an urban Indian study 显示文摘Kota SK Kota SK Jammula S 2011Ind J Endocrinol Metab2011,154,:1
9Renin-angiotensin systemactivity in vitamin D deficient, obese individuals with hypertension:An urban Indian study显示文摘Kota SK Kota SK Jammula S 2011Indian J Endocrinol Metab2011,154,:1
10Tet proteins connect the O-linked N-acetylglucosamine transferase Ogt to chromatin in embryonic stem cells显示文摘Vella P Scelfo A Jammula S 2013Mol Cell2013,49,4:1
11Renin-angiotensin system activity in vitamin D deficient, obese individuals with hypertension:an urban Indian study 显示文摘Kota SK Jammula S 2011Indian J Endocrinol Metab2011,15,4:1
12Tet proteins connect the O-linked N-acetylglucosamine transferase OGT to chromatin in embryonic stem cells显示文摘Vella P Scelfo A Jammula S 2013Mol Cell2013,49,4:1
13Hypertriglyceridemia-induced recurrent acute pancreatitis:a case-based review显示文摘Kota SK Kota SK Jammula S 2012Indian J Endocrinol Metab2012,16,1:1
14Clinical profile of coexisting conditions in type 1 diabetes mellitus patients显示文摘Kota SK Meher LK Jammula S 2012Diabetes Metab Syndr2012,6,2:1
15Renin-angiotensin system activity in vitamin D deficient, obese individuals with hyperten sion: an urban Indian study显示文摘Kota SK Kota SK Jammula S 2011Indian J Endocrinol Metab2011,15,4:1
16Clinical profile of coexisting coNDItions in type 1diabetes mellitus patients显示文摘Kota SK Meher LK Jammula S 2012Diabetes Metab Syndr2012,6,2:1
17Effect of vitamin D supplemen- tation in type 2 diabetes patients with pulmonary tuberculosis 显示文摘Kota SK Jammula S Kota SK 2011Di- abetes Metab Syndr2011,5,2:1
18Aberrant angiogenesis: the gateway to diabetic complications 显示文摘Kota SK Meher LK Jammula S 2012Indian J Endocrinol Metab2012,16,6:1
19Nutraceuticals in dyslipidemia management显示文摘Kota S K Jammula S Krishna S V 2013Journal of Medical Nutrition and Nutraceuticals2013,2,1:1
20Effect of vitamin D supplementa- tion in type 2 diabetes patients with pulmonary tuberculosis显示文摘Kota SK Jammula S Kota SK 2011Dia- betes Metab Syndr2011,5,2:1
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