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| 1 | 中国两栖动物保护需求总述显示文摘通过对中国两栖动物物种生物多样性现状的全面分析,与世界许多国家相比,中国是一个重要的全球优先保护地区.横断山区、南岭山区和武夷山区3个区域的两栖动物物种多样性特别丰富.有尾两栖类物种较无尾类受胁程度更高.几个物种数相对较少的铃蟾科、隐腮鲵科、小鲵科和蝾螈科显示出了高的受胁倾向.像世界其它地方一样,高海拔地区溪流繁殖的森林物种受胁程度更高.对中国两栖动物而言,生境丧失、污染和过度捕捉是最主要的致危因素.过度捕捉虽然影响不如生境丧失深远,但它更可能导致一个物种种群的快速衰落.针对5个方面的保护挑战,提出了优先研究领域和保护行动方面的建议. | 谢锋 刘惠宁 Simon N Stuart Janice S Chanson Neil A Cox Debra L Fischman | 2006 | 中国科学(C辑)2006，36，6： | 28 |
| 2 | Conservation needs of amphibians in China: A review显示文摘The conservation status of all the amphibians in China is analyzed,and the country is shown to be a global priority for conservation in comparison to many other countries of the world.Three Chinese regions are particularly rich in amphibian diversity:Hengduan,Nanling,and Wuyi mountains.Sala-manders are more threatened than frogs and toads.Several smaller families show a high propensity to become seriously threatened:Bombinatoridae,Cryptobranchidae,Hynobiidae and Salamandridae.Like other parts of the world,stream-breeding,high-elevation forest amphibians have a much higher likeli-hood of being seriously threatened.Habitat loss,pollution,and over-harvesting are the most serious threats to Chinese amphibians.Over-harvesting is a less pervasive threat than habitat loss,but it is more likely to drive a species into rapid decline.Five conservation challenges are mentioned with recommendations for the highest priority research and conservation actions. | Michael Wai Neng LAU Simon N STUART Janice S CHANSON Neil A COX Debra L FISCHMAN | 2007 | Science China(Life Sciences)2007，50，2： | 12 |
| 3 | Subcurative radiation significantly increases cell proliferation, invasion, and migration of primary glioblastoma multiforme in vivo显示文摘Tumor cell proliferation, infiltration, migration, and neovascularization are known causes of treatment resistance in glioblastoma multiforme(GBM). The purpose of this study was to determine the effect of radiation on the growth characteristics of primary human GBM developed in a nude rat. Primary GBM cells grown from explanted GBM tissues were implanted orthotopically in nude rats. Tumor growth was confirmed by magnetic resonance imaging on day 77(baseline) after implantation. The rats underwent irradiation to a dose of 50 Gy delivered subcuratively on day 84 postimplantation(n = 8), or underwent no radiation(n = 8). Brain tissues were obtained on day 112(nonirradiated) or day 133(irradiated). Immunohistochemistry was performed to determine tumor cell proliferation(Ki-67) and to assess the expression of infiltration marker(matrix metalloproteinase-2, MMP-2) and cell migration marker(CD44). Tumor neovascularization was assessed by microvessel density using von-Willebrand factor(vWF) staining. Magnetic resonance imaging showed well-developed, infiltrative tumors in 11 weeks postimplantation. The proportion of Ki-67-positive cells in tumors undergoing radiation was(71 ± 15)% compared with(25 ± 12)% in the nonirradiated group(P = 0.02). The number of MMP-2-positive areas and proportion of CD44-positive cells were also high in tumors receiving radiation, indicating great invasion and infiltration. Microvessel density analysis did not show a significant difference between nonirradiated and irradiated tumors. Taken together, we found that subcurative radiation significantly increased proliferation, invasion, and migration of primary GBM. Our study provides insights into possible mechanisms of treatment resistance following radiation therapy for GBM. | Adarsh Shankar Sanath Kumar Asm Iskander Nadimpalli RS Varma Branislava Janic Ana deCarvalho Tom Mikkelsen Joseph A Frank Meser M Ali Robert A Knight Stephen Brown Ali S Arbab | 2014 | Chinese Journal of Cancer2014，33，3： | 5 |
| 4 | Trade-off between carbon dioxide emissions and logistics costs based on multiobjective optimization显示文摘 | Kim N S Janic M Wee B | 2009 | Transportation Research Record2009，2139，： | 1 |
| 5 | Adeno-associated viral vector-mediated hypoxia response element-regulated gene expression in mouse ischemic heart model显示文摘 | Hua S Janice AH Yuet WK | 2002 | Proc Natl Acad Sci USA2002，99，14： | 1 |
| 6 | Barriers to blood glucose monitoring in a multiethnic community显示文摘 | David S | 2002 | Diabetes Care2002，25，10： | 1 |
| 7 | Studies on the microbial populations of the rhizosphere of big sagebrush (Artemisia tridentata)显示文摘 | Antony J B Janice L S Heather M K | 2004 | Journal Indian Microbiology and Biotechnology2004，31，6： | 1 |
| 8 | Preclinical and clinical evaluations of ABX-EGF, a fully human anti-epidermal growth factor receptor antibody显示文摘 | Kenneth A Foon Xiao-Dong Yang Louis M Weiner Arie S Belldegrun Robert A Figlin Jeffrey Crawford Eric K Rowinsky Janice P Dutcher Nicholas J Vogelzang Jared Gollub John A Thompson Garry Schwartz Ronald M Bukowski Lorin K Roskos Gisela M Schwab | 2004 | International Journal of Radiation Oncology Biology Physics2004，，3： | 1 |
| 9 | Traffic-related air pollution near busy roads: The east bay children's respiratory health study显示文摘 | JANICE JK SVETLANA S MICHAEL L | 2004 | Am J Res Critical Care Med2004，170，5： | 1 |
| 10 | Pripherally inserted central catheters for parenteral nutrition: a comparison with centrally inserted catheters 显示文摘 | Donald RD Noreen P Janice S | 1999 | JPEN1999，23，2： | 1 |
| 11 | AngiotensinII-induced change in G-proteins显示文摘 | Karen A Janice | 1992 | Hypertension1992，19，： | 1 |
| 12 | The Art and Science of Risk Management显示文摘 | Wanju S D Gretchen S D | 2006 | Drug Safety2006，28，1： | 1 |
| 13 | Effective treatment of metastatic forms of Epstein-Barr virus-associated naso- pharyngeal carcinoma with a novel adenovirus-based a- doptive immunotherapy 显示文摘 | Corey S Janice T Leone B | 2012 | Cancer Res2012，72，5： | 1 |
| 14 | The recent evolution of pentachlorophenol(PCP) -4-monooxygenaso (PcpB) and associated pathways for bacterial degradation of PCP显示文摘 | Carina M J Janice L S | 2007 | Biodegradation2007，18，： | 1 |
| 15 | Preclinical and clinical evaluations of ABX-EGF, a fully human anti-epidermal growth factor receptor antibody显示文摘 | Kenneth A Foon Xiao-Dong Yang Louis M Weiner Arie S Belldegrun Robert A Figlin Jeffrey Crawford Eric K Rowinsky Janice P Dutcher Nicholas J Vogelzang Jared Gollub John A Thompson Garry Schwartz Ronald M Bukowski Lorin K Roskos Gisela M Schwab | 2004 | International Journal of Radiation Oncology, Biology, Physics2004，，3： | 1 |
| 16 | Free port fallout: gender, employment , and migration on Margarita island 显示文摘 | JANICE M CHARLES S | 1986 | Annals of Tourism Research1986，13，3： | 1 |
| 17 | High-fiber cereal reduces postprandial insulin responses in hyperinsulinemic but not normoinsulinemic subjects显示文摘 | THOMAS M S JANICE E CAMPBELL | 2004 | Diabetes Care2004，27，： | 1 |
| 18 | Clinical nurses' understanding of autono- my :Accomplishing patient goals through interdependent practice 显示文摘 | Janice S Katherine S Dianne T | 2004 | The Journal of Nursing Administration2004，34，10： | 1 |
| 19 | Trade-off between carbon dioxide emissions and logistics costs based on multi-objective optimization 显示文摘 | Kim N S Janic M Wee B | 2009 | Transportation Research Record2009，21，39： | 1 |
| 20 | Proteomic identification of a novel protein regulated in CA1 and CA3 hippocampal regions during intermittent hypoxia显示文摘 | Jon B K David G William M P Visith T Janice A S Leroy R S Shang Z G Jian C Evelyne G | 2003 | Respir Physiol Neurobiol2003，136，： | 1 |
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